irinotecan hydrochloride trihydrate and its Impurities
Irinotecan Hydrochloride Trihydrate main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. It is sold under the brand name Camptosar. Reference standards of Irinotecan Hydrochloride Trihydrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Irinotecan Hydrochloride Trihydrate - Impurity K
(4S)-4-Ethyl-4-hydroxy-11-(1-hydroxypropyl)-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3', 4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate
Catalogue No.:PA 09 16110
CAS :
2508174-07-8
Molecular Formula : C34H40N4O7
Molecular Weight : 616.72
Irinotecan - Impurity L (Hydrochloride Trihydrate Salt)
(4R)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate Hydrochloride Trihydrate
Catalogue No.:PA 09 16120
CAS :
NA
Molecular Formula : C33H45ClN4O9
Molecular Weight : 677.18
Irinotecan - Impurity L (Hydrochloride Salt)
(4R)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate Hydrochloride
Catalogue No.:PA 09 16121
CAS :
1992961-26-8
Molecular Formula : C33H39ClN4O6
Molecular Weight : 623.15
