istradefylline and its Impurities
Istradefylline used as an add-on treatment to levodopa/carbidopa in adults with Parkinson's disease experiencing "off" episodes. It is sold under the brand name Nourianz. Reference standards of Istradefylline API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)
rel-8,8'-((1R,2R,3S,4S)-2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-diyl)bis(1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione)
Catalogue No.:PA 09 1361000
CAS :
702697-27-6
Molecular Formula : C40H48N8O8
Molecular Weight : 768.87


(E)-N-(6-Amino-1,3-diethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-(3,4-dimethoxyphenyl)acrylamide
(E)-N-(6-Amino-1,3-diethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-(3,4-dimethoxyphenyl)acrylamide
Catalogue No.:PA 09 1361005
CAS :
187393-68-6
Molecular Formula : C19H24N4O5
Molecular Weight : 388.42