ivabradine and its Impurities

Ivabradine is used for the symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm who cannot take beta blockers. It is marketed under the trade name Corlanor. Reference standards of Ivabradine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 46 results for ivabradine Impurities
PA 09 58000

Ivabradine

Ivabradine

  • Catalogue No.:PA 09 58000

  • CAS :

    155974-00-8

  • Molecular Formula : C27H36N2O5

  • Molecular Weight : 468.59

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PA STI 025060

Dehydro Ivabradine-d3

Dehydro Ivabradine-d3

  • Catalogue No.:PA STI 025060

  • CAS :

    1795787-01-7

  • Molecular Formula : C27H31D3N2O5

  • Molecular Weight : 469.59

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PA STI 028660

N-Demethyl Ivabradine-d6 Hydrochloride

N-Demethyl Ivabradine-d6 Hydrochloride

  • Catalogue No.:PA STI 028660

  • CAS :

    NA

  • Molecular Formula : C26H29D6ClN2O5

  • Molecular Weight : 497.06

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PA STI 054520

Ivabradine-d3 Hydrochloride

Ivabradine-d3 Hydrochloride

  • Catalogue No.:PA STI 054520

  • CAS :

    1217809-61-4

  • Molecular Formula : C27H34D3ClN2O5

  • Molecular Weight : 508.06

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PA STI 054521

Ivabradine-d6

Ivabradine-d6

  • Catalogue No.:PA STI 054521

  • CAS :

    NA

  • Molecular Formula : C27H30D6N2O5

  • Molecular Weight : 474.62

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PA 09 0581000

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepine 3-Oxide

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepine 3-Oxide

  • Catalogue No.:PA 09 0581000

  • CAS :

    NA

  • Molecular Formula : C27H36N2O6

  • Molecular Weight : 484.59

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PA 09 0581001

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione Oxalate

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione Oxalate

  • Catalogue No.:PA 09 0581001

  • CAS :

    NA

  • Molecular Formula : C29H36N2O10

  • Molecular Weight : 572.61

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PA 09 0581002

[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]-carbamic acid ethyl ester

[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]-carbamic acid ethyl ester

  • Catalogue No.:PA 09 0581002

  • CAS :

    869856-10-0

  • Molecular Formula : C14H19NO4

  • Molecular Weight : 265.31

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PA 09 0581003

N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide

N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide

  • Catalogue No.:PA 09 0581003

  • CAS :

    NA

  • Molecular Formula : C14H19NO3

  • Molecular Weight : 249.31

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PA 09 0581004

Ethyl (E)-N-((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)formimidate

Ethyl (E)-N-((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)formimidate

  • Catalogue No.:PA 09 0581004

  • CAS :

    NA

  • Molecular Formula : C14H19NO3

  • Molecular Weight : 249.31

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PA 09 0581005

3-(3-((((1R,3S,4R,6S,7S)-3,4-Dimethoxybicyclo[4.2.0]octan-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

3-(3-((((1R,3S,4R,6S,7S)-3,4-Dimethoxybicyclo[4.2.0]octan-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581005

  • CAS :

    NA

  • Molecular Formula : C27H42N2O5

  • Molecular Weight : 474.64

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PA 09 0581006

3-(3-((((1S,3R,4S,6R,7S)-3,4-Dimethoxybicyclo[4.2.0]octan-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

3-(3-((((1S,3R,4S,6R,7S)-3,4-Dimethoxybicyclo[4.2.0]octan-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581006

  • CAS :

    NA

  • Molecular Formula : C27H42N2O5

  • Molecular Weight : 474.64

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PA 09 0581007

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-5-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-5-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581007

  • CAS :

    2253977-80-7

  • Molecular Formula : C27H36N2O6

  • Molecular Weight : 484.59

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PA 09 0581008

3-(3-((3-Chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

3-(3-((3-Chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581008

  • CAS :

    NA

  • Molecular Formula : C27H37ClN2O5

  • Molecular Weight : 505.05

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PA 09 0581009

3-Hydroxy Ivabradine

3-Hydroxy Ivabradine

  • Catalogue No.:PA 09 0581009

  • CAS :

    304464-98-0

  • Molecular Formula : C26H34N2O5

  • Molecular Weight : 454.57

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PA 09 0241008

7-(3-((((R)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-2,3-dimethoxy-5,7,8,9-tetrahydro-6H-benzo[7]annulen-6-one hydrochloride

7-(3-((((R)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-2,3-dimethoxy-5,7,8,9-tetrahydro-6H-benzo[7]annulen-6-one hydrochloride

  • Catalogue No.:PA 09 0241008

  • CAS :

    148849-68-7

  • Molecular Formula : C28H38ClNO5

  • Molecular Weight : 504.06

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PA 09 0581010

3-(2,3-Dimethoxy-6-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-7-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide

3-(2,3-Dimethoxy-6-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-7-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide

  • Catalogue No.:PA 09 0581010

  • CAS :

    NA

  • Molecular Formula : C28H37NO6

  • Molecular Weight : 483.61

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PA 09 0581011

3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride

3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride

  • Catalogue No.:PA 09 0581011

  • CAS :

    1796933-38-4

  • Molecular Formula : C27H37ClN2O5

  • Molecular Weight : 505.05

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PA 09 0581012

2-(3,4-Dimethoxyphenyl)-N-(2-oxoethyl)acetamide

2-(3,4-Dimethoxyphenyl)-N-(2-oxoethyl)acetamide

  • Catalogue No.:PA 09 0581012

  • CAS :

    1082829-01-3

  • Molecular Formula : C12H15NO4

  • Molecular Weight : 237.26

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PA 09 0581013

4,5-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile

4,5-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile

  • Catalogue No.:PA 09 0581013

  • CAS :

    1132076-14-2

  • Molecular Formula : C11H11NO2

  • Molecular Weight : 189.21

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PA 09 0581014

3-(3-Bromo-4,5-dimethoxyphenyl)propanenitrile

3-(3-Bromo-4,5-dimethoxyphenyl)propanenitrile

  • Catalogue No.:PA 09 0581014

  • CAS :

    2229445-09-2

  • Molecular Formula : C11H12BrNO2

  • Molecular Weight : 270.13

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PA 09 0581015

1-(((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-3-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)urea

1-(((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-3-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)urea

  • Catalogue No.:PA 09 0581015

  • CAS :

    NA

  • Molecular Formula : C23H28N2O5

  • Molecular Weight : 412.49

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PA 09 0581016

N-Nitroso N-Desmethyl DEBA

N-Nitroso N-Desmethyl DEBA

  • Catalogue No.:PA 09 0581016

  • CAS :

    NA

  • Molecular Formula : C9H20N2O3

  • Molecular Weight : 204.27

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PA 09 0581017

N-Nitroso N-Desmethyl Ivabradine

N-Nitroso N-Desmethyl Ivabradine

  • Catalogue No.:PA 09 0581017

  • CAS :

    NA

  • Molecular Formula : C26H33N3O6

  • Molecular Weight : 483.57

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PA 09 0581018

(S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide

(S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide

  • Catalogue No.:PA 09 0581018

  • CAS :

    2512206-14-1

  • Molecular Formula : C14H19NO3

  • Molecular Weight : 249.31

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PA 09 0581019

(R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

(R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581019

  • CAS :

    2724918-59-4

  • Molecular Formula : C26H34N2O5

  • Molecular Weight : 454.57

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PA 09 0581020

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxydecahydro-2H-benzo[d]azepin-2-one Hydrochloride

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxydecahydro-2H-benzo[d]azepin-2-one Hydrochloride

  • Catalogue No.:PA 09 0581020

  • CAS :

    NA

  • Molecular Formula : C27H43ClN2O5

  • Molecular Weight : 511.1

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PA 09 0581021

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,5-dihydro-2H-benzo[d]azepine-2,4(3H)-dione

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,5-dihydro-2H-benzo[d]azepine-2,4(3H)-dione

  • Catalogue No.:PA 09 0581021

  • CAS :

    1629315-02-1

  • Molecular Formula : C27H34N2O6

  • Molecular Weight : 482.58

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PA 09 0581022

(S)-3-Chloro-N-((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylpropan-1-amine

(S)-3-Chloro-N-((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylpropan-1-amine

  • Catalogue No.:PA 09 0581022

  • CAS :

    1031767-71-1

  • Molecular Formula : C15H22ClNO2

  • Molecular Weight : 283.8

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PA 09 0581023

3-(3-Bromopropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

3-(3-Bromopropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581023

  • CAS :

    1192174-72-3

  • Molecular Formula : C15H20BrNO3

  • Molecular Weight : 342.23

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PA 09 0581025

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-1-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-1-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581025

  • CAS :

    2511244-96-3

  • Molecular Formula : C27H36N2O6

  • Molecular Weight : 484.59

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PA 09 0581024

3-(3-(((4-Hydroxy-3-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

3-(3-(((4-Hydroxy-3-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581024

  • CAS :

    2247881-27-0

  • Molecular Formula : C26H34N2O5

  • Molecular Weight : 454.57

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PA 09 0581026

(S)-3-(3-(((4-Hydroxy-3-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

(S)-3-(3-(((4-Hydroxy-3-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581026

  • CAS :

    304465-03-0

  • Molecular Formula : C26H34N2O5

  • Molecular Weight : 454.57

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PA 09 0581027

Ivabradine Dimer Impurity

Ivabradine Dimer Impurity

  • Catalogue No.:PA 09 0581027

  • CAS :

    NA

  • Molecular Formula : C41H53N3O8

  • Molecular Weight : 715.89

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PA 09 0581028

(S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylnitrous Amide

(S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylnitrous Amide

  • Catalogue No.:PA 09 0581028

  • CAS :

    NA

  • Molecular Formula : C12H16N2O3

  • Molecular Weight : 236.27

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PA 09 0581029

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-5-hydroxy-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-5-hydroxy-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581029

  • CAS :

    NA

  • Molecular Formula : C27H34N2O6

  • Molecular Weight : 482.58

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PA 09 0581030

7,8-Dimethoxy-3-nitroso-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

7,8-Dimethoxy-3-nitroso-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one

  • Catalogue No.:PA 09 0581030

  • CAS :

    NA

  • Molecular Formula : C12H14N2O4

  • Molecular Weight : 250.25

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PA 09 0581031

8-Demethyl Ivabradine Hydrochloride

8-Demethyl Ivabradine Hydrochloride

  • Catalogue No.:PA 09 0581031

  • CAS :

    NA

  • Molecular Formula : C26H35ClN2O5

  • Molecular Weight : 491.03

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PA 09 0581032

(R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2,3-dihydro-1H-benzo[d]azepine-1,4(5H)-dione

(R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2,3-dihydro-1H-benzo[d]azepine-1,4(5H)-dione

  • Catalogue No.:PA 09 0581032

  • CAS :

    NA

  • Molecular Formula : C27H34N2O6

  • Molecular Weight : 482.58

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PA 09 0581033

7-Demethyl Ivabradine Hydrochloride

7-Demethyl Ivabradine Hydrochloride

  • Catalogue No.:PA 09 0581033

  • CAS :

    NA

  • Molecular Formula : C26H35ClN2O5

  • Molecular Weight : 491.03

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PA STI 089846

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-bis(methoxy-d3)-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one Hydrochloride

(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-bis(methoxy-d3)-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one Hydrochloride

  • Catalogue No.:PA STI 089846

  • CAS :

    2070009-63-9

  • Molecular Formula : C27H31D6ClN2O5

  • Molecular Weight : 511.09

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PA 09 0581034

(Z)-3-(2-Bromo-4,5-dimethoxyphenyl)-2-cyanoacrylic Acid

(Z)-3-(2-Bromo-4,5-dimethoxyphenyl)-2-cyanoacrylic Acid

  • Catalogue No.:PA 09 0581034

  • CAS :

    1208977-76-7

  • Molecular Formula : C12H10BrNO4

  • Molecular Weight : 312.12

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PA 09 0581035

Potassium trifluoro((5-fluoro-2-methoxybenzamido)methyl)borate

Potassium trifluoro((5-fluoro-2-methoxybenzamido)methyl)borate

  • Catalogue No.:PA 09 0581035

  • CAS :

    2089246-64-8

  • Molecular Formula : C9H9BF4KNO2

  • Molecular Weight : 289.08

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PA 09 0581036

2-(2-(Chloromethyl)-4,5-dimethoxyphenyl)-N-methylethan-1-amine

2-(2-(Chloromethyl)-4,5-dimethoxyphenyl)-N-methylethan-1-amine

  • Catalogue No.:PA 09 0581036

  • CAS :

    NA

  • Molecular Formula : C12H18ClNO2

  • Molecular Weight : 243.73

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PA 09 0581037

Ethyl 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropanoate

Ethyl 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropanoate

  • Catalogue No.:PA 09 0581037

  • CAS :

    NA

  • Molecular Formula : C14H16BrNO4

  • Molecular Weight : 342.19

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PA 09 0581038

3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid

3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid

  • Catalogue No.:PA 09 0581038

  • CAS :

    41234-23-5

  • Molecular Formula : C11H12O4

  • Molecular Weight : 208.21

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