ivacaftor and its Impurities

Ivacaftor is used for the treatment of cystic fibrosis in people having one of several specific mutations in the cystic fibrosis transmembrane conductance regulator protein. It is one of the most expensive drugs. Reference standards of Ivacaftor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 32 results for ivacaftor Impurities
PA 09 40000

Ivacaftor

Ivacaftor

  • Catalogue No.:PA 09 40000

  • CAS :

    873054-44-5

  • Molecular Formula : C24H28N2O3

  • Molecular Weight : 392.49

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PA 09 40510

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid

  • Catalogue No.:PA 09 40510

  • CAS :

    13721-01-2

  • Molecular Formula : C10H7NO3

  • Molecular Weight : 189.17

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PA 09 40520

1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester

1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester

  • Catalogue No.:PA 09 40520

  • CAS :

    52980-28-6

  • Molecular Formula : C12H11NO3

  • Molecular Weight : 217.22

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PA 09 40530

5-Amino-2,4-di-tert-butylphenol

5-Amino-2,4-di-tert-butylphenol

  • Catalogue No.:PA 09 40530

  • CAS :

    873055-58-4

  • Molecular Formula : C14H23NO

  • Molecular Weight : 221.34

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PA 09 40540

N-(3,5-Di-tert-butyl-2-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(3,5-Di-tert-butyl-2-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 40540

  • CAS :

    873051-52-6

  • Molecular Formula : C24H28N2O3

  • Molecular Weight : 392.49

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PA 09 40550

Ivacaftor N-glucuronide

Ivacaftor N-glucuronide

  • Catalogue No.:PA 09 40550

  • CAS :

    NA

  • Molecular Formula : C30H36N2O9

  • Molecular Weight : 568.61

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PA 09 40560

Ivacaftor Carboxylic Acid

Ivacaftor Carboxylic Acid

  • Catalogue No.:PA 09 40560

  • CAS :

    1246213-24-0

  • Molecular Formula : C24H26N2O5

  • Molecular Weight : 422.47

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PA 09 40570

Hydroxymethyl Ivacaftor

Hydroxymethyl Ivacaftor

  • Catalogue No.:PA 09 40570

  • CAS :

    1246213-23-9

  • Molecular Formula : C24H28N2O4

  • Molecular Weight : 408.49

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PA 09 0401000

diethyl 2-((phenylamino)methylene)malonate

diethyl 2-((phenylamino)methylene)malonate

  • Catalogue No.:PA 09 0401000

  • CAS :

    54535-22-7

  • Molecular Formula : C14H17NO4

  • Molecular Weight : 263.29

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PA 09 0401001

De-Alkylated Ivacaftor

De-Alkylated Ivacaftor

  • Catalogue No.:PA 09 0401001

  • CAS :

    873054-39-8

  • Molecular Formula : C20H20N2O3

  • Molecular Weight : 336.39

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PA STI 089107

Ivacaftor D4

Ivacaftor D4

  • Catalogue No.:PA STI 089107

  • CAS :

    NA

  • Molecular Formula : C24H24D4N2O3

  • Molecular Weight : 396.52

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PA 09 0401002

4-Hydroxyquinoline-3-carboxylic Acid

4-Hydroxyquinoline-3-carboxylic Acid

  • Catalogue No.:PA 09 0401002

  • CAS :

    34785-11-0

  • Molecular Formula : C10H7NO3

  • Molecular Weight : 189.17

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PA STI 089190

Ivacaftor D18

Ivacaftor D18

  • Catalogue No.:PA STI 089190

  • CAS :

    1413431-05-6

  • Molecular Formula : C24H10D18N2O3

  • Molecular Weight : 410.61

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PA 09 0401003

2,4-Di-tert-butyl-6-nitrophenol

2,4-Di-tert-butyl-6-nitrophenol

  • Catalogue No.:PA 09 0401003

  • CAS :

    20039-94-5

  • Molecular Formula : C14H21NO3

  • Molecular Weight : 251.33

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PA 09 0401004

4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid

4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid

  • Catalogue No.:PA 09 0401004

  • CAS :

    NA

  • Molecular Formula : C28H32N2O6

  • Molecular Weight : 492.57

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PA 09 0401005

1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

  • Catalogue No.:PA 09 0401005

  • CAS :

    NA

  • Molecular Formula : C10H6N2O4

  • Molecular Weight : 218.17

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PA 09 0401006

2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

  • Catalogue No.:PA 09 0401006

  • CAS :

    2760759-55-3

  • Molecular Formula : C34H33N3O5

  • Molecular Weight : 563.65

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PA 09 0401007

N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401007

  • CAS :

    NA

  • Molecular Formula : C20H19N3O4

  • Molecular Weight : 365.39

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PA 09 0401008

Ivacaftor Nitroso Impurity

Ivacaftor Nitroso Impurity

  • Catalogue No.:PA 09 0401008

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

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PA 09 0401009

5-Amino-2,4-di-tert-butylphenyl methyl carbonate

5-Amino-2,4-di-tert-butylphenyl methyl carbonate

  • Catalogue No.:PA 09 0401009

  • CAS :

    1182822-31-6

  • Molecular Formula : C16H25NO3

  • Molecular Weight : 279.38

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PA 09 0401010

N-Nitroso Ivacaftor Ortho Isomer

N-Nitroso Ivacaftor Ortho Isomer

  • Catalogue No.:PA 09 0401010

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

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PA 09 0401011

Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate

Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate

  • Catalogue No.:PA 09 0401011

  • CAS :

    NA

  • Molecular Formula : C12H10N2O4

  • Molecular Weight : 246.22

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PA 09 0401012

2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate

2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate

  • Catalogue No.:PA 09 0401012

  • CAS :

    873055-56-2

  • Molecular Formula : C16H23NO5

  • Molecular Weight : 309.36

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PA STI 089610

Ivacaftor-d19

Ivacaftor-d19

  • Catalogue No.:PA STI 089610

  • CAS :

    1413431-22-7

  • Molecular Formula : C24H9D19N2O3

  • Molecular Weight : 411.61

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PA 09 0401013

Diethyl 2-((nitroso(phenyl)amino)methylene)malonate

Diethyl 2-((nitroso(phenyl)amino)methylene)malonate

  • Catalogue No.:PA 09 0401013

  • CAS :

    NA

  • Molecular Formula : C14H16N2O5

  • Molecular Weight : 292.29

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PA 09 0401014

N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401014

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

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PA 09 0401015

Ivacaftor Amine Impurity

Ivacaftor Amine Impurity

  • Catalogue No.:PA 09 0401015

  • CAS :

    2760759-58-6

  • Molecular Formula : C24H28N2O3

  • Molecular Weight : 392.5

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PA 09 0401016

2-(Aminomethyl)-3,5-di-tert-butylphenol

2-(Aminomethyl)-3,5-di-tert-butylphenol

  • Catalogue No.:PA 09 0401016

  • CAS :

    84210-35-5

  • Molecular Formula : C15H25NO

  • Molecular Weight : 235.37

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PA 09 0401017

N-(4-(tert-Butyl)-3,6-dioxocyclohexa-1,4-dien-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(4-(tert-Butyl)-3,6-dioxocyclohexa-1,4-dien-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401017

  • CAS :

    NA

  • Molecular Formula : C20H18N2O4

  • Molecular Weight : 350.37

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PA STI 089979

Ivacaftor 13C6

Ivacaftor 13C6

  • Catalogue No.:PA STI 089979

  • CAS :

    NA

  • Molecular Formula : C1813C6H28N2O3

  • Molecular Weight : 398.45

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PA 09 0401018

2,4-Di-tert-butyl-5-nitrophenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

2,4-Di-tert-butyl-5-nitrophenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

  • Catalogue No.:PA 09 0401018

  • CAS :

    2760759-57-5

  • Molecular Formula : C24H26N2O5

  • Molecular Weight : 422.48

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PA 09 0401019

4-Oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide

4-Oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401019

  • CAS :

    325779-54-2

  • Molecular Formula : C16H12N2O2

  • Molecular Weight : 264.28

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CPHI INDIA- 28, 30 November