ivacaftor and its Impurities

Ivacaftor is used for the treatment of cystic fibrosis in people having one of several specific mutations in the cystic fibrosis transmembrane conductance regulator protein. It is one of the most expensive drugs. Reference standards of Ivacaftor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 35 results for ivacaftor Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 09 40000

Ivacaftor

Ivacaftor

  • Catalogue No.:PA 09 40000

  • CAS :

    873054-44-5

  • Molecular Formula : C24H28N2O3

  • Molecular Weight : 392.49

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Drug Reference Standards & Impurity Synthesis in India
PA 09 40510

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid

  • Catalogue No.:PA 09 40510

  • CAS :

    13721-01-2

  • Molecular Formula : C10H7NO3

  • Molecular Weight : 189.17

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Drug Reference Standards & Impurity Synthesis in India
PA 09 40520

1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester

1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester

  • Catalogue No.:PA 09 40520

  • CAS :

    52980-28-6

  • Molecular Formula : C12H11NO3

  • Molecular Weight : 217.22

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Drug Reference Standards & Impurity Synthesis in India
PA 09 40530

5-Amino-2,4-di-tert-butylphenol

5-Amino-2,4-di-tert-butylphenol

  • Catalogue No.:PA 09 40530

  • CAS :

    873055-58-4

  • Molecular Formula : C14H23NO

  • Molecular Weight : 221.34

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Drug Reference Standards & Impurity Synthesis in India
PA 09 40540

N-(3,5-Di-tert-butyl-2-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(3,5-Di-tert-butyl-2-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 40540

  • CAS :

    873051-52-6

  • Molecular Formula : C24H28N2O3

  • Molecular Weight : 392.49

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Drug Reference Standards & Impurity Synthesis in India
PA 09 40550

Ivacaftor N-glucuronide

Ivacaftor N-glucuronide

  • Catalogue No.:PA 09 40550

  • CAS :

    NA

  • Molecular Formula : C30H36N2O9

  • Molecular Weight : 568.61

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Drug Reference Standards & Impurity Synthesis in India
PA 09 40560

Ivacaftor Carboxylic Acid

Ivacaftor Carboxylic Acid

  • Catalogue No.:PA 09 40560

  • CAS :

    1246213-24-0

  • Molecular Formula : C24H26N2O5

  • Molecular Weight : 422.47

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Drug Reference Standards & Impurity Synthesis in India
PA 09 40570

Hydroxymethyl Ivacaftor

Hydroxymethyl Ivacaftor

  • Catalogue No.:PA 09 40570

  • CAS :

    1246213-23-9

  • Molecular Formula : C24H28N2O4

  • Molecular Weight : 408.49

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401000

diethyl 2-((phenylamino)methylene)malonate

diethyl 2-((phenylamino)methylene)malonate

  • Catalogue No.:PA 09 0401000

  • CAS :

    54535-22-7

  • Molecular Formula : C14H17NO4

  • Molecular Weight : 263.29

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401001

De-Alkylated Ivacaftor

De-Alkylated Ivacaftor

  • Catalogue No.:PA 09 0401001

  • CAS :

    873054-39-8

  • Molecular Formula : C20H20N2O3

  • Molecular Weight : 336.39

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089107

Ivacaftor D4

Ivacaftor D4

  • Catalogue No.:PA STI 089107

  • CAS :

    NA

  • Molecular Formula : C24H24D4N2O3

  • Molecular Weight : 396.52

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401002

4-Hydroxyquinoline-3-carboxylic Acid

4-Hydroxyquinoline-3-carboxylic Acid

  • Catalogue No.:PA 09 0401002

  • CAS :

    34785-11-0

  • Molecular Formula : C10H7NO3

  • Molecular Weight : 189.17

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089190

Ivacaftor D18

Ivacaftor D18

  • Catalogue No.:PA STI 089190

  • CAS :

    1413431-05-6

  • Molecular Formula : C24H10D18N2O3

  • Molecular Weight : 410.61

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401003

2,4-Di-tert-butyl-6-nitrophenol

2,4-Di-tert-butyl-6-nitrophenol

  • Catalogue No.:PA 09 0401003

  • CAS :

    20039-94-5

  • Molecular Formula : C14H21NO3

  • Molecular Weight : 251.33

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401004

4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid

4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid

  • Catalogue No.:PA 09 0401004

  • CAS :

    NA

  • Molecular Formula : C28H32N2O6

  • Molecular Weight : 492.57

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401005

1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

  • Catalogue No.:PA 09 0401005

  • CAS :

    NA

  • Molecular Formula : C10H6N2O4

  • Molecular Weight : 218.17

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401006

2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

  • Catalogue No.:PA 09 0401006

  • CAS :

    2760759-55-3

  • Molecular Formula : C34H33N3O5

  • Molecular Weight : 563.65

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401007

N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401007

  • CAS :

    NA

  • Molecular Formula : C20H19N3O4

  • Molecular Weight : 365.39

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401008

Ivacaftor Nitroso Impurity

Ivacaftor Nitroso Impurity

  • Catalogue No.:PA 09 0401008

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401009

5-Amino-2,4-di-tert-butylphenyl methyl carbonate

5-Amino-2,4-di-tert-butylphenyl methyl carbonate

  • Catalogue No.:PA 09 0401009

  • CAS :

    1182822-31-6

  • Molecular Formula : C16H25NO3

  • Molecular Weight : 279.38

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401010

N-Nitroso Ivacaftor Ortho Isomer

N-Nitroso Ivacaftor Ortho Isomer

  • Catalogue No.:PA 09 0401010

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401011

Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate

Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate

  • Catalogue No.:PA 09 0401011

  • CAS :

    NA

  • Molecular Formula : C12H10N2O4

  • Molecular Weight : 246.22

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401012

2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate

2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate

  • Catalogue No.:PA 09 0401012

  • CAS :

    873055-56-2

  • Molecular Formula : C16H23NO5

  • Molecular Weight : 309.36

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089610

Ivacaftor-d19

Ivacaftor-d19

  • Catalogue No.:PA STI 089610

  • CAS :

    1413431-22-7

  • Molecular Formula : C24H9D19N2O3

  • Molecular Weight : 411.61

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401013

Diethyl 2-((nitroso(phenyl)amino)methylene)malonate

Diethyl 2-((nitroso(phenyl)amino)methylene)malonate

  • Catalogue No.:PA 09 0401013

  • CAS :

    NA

  • Molecular Formula : C14H16N2O5

  • Molecular Weight : 292.29

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401014

N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401014

  • CAS :

    NA

  • Molecular Formula : C24H27N3O4

  • Molecular Weight : 421.5

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401015

Ivacaftor Amine Impurity

Ivacaftor Amine Impurity

  • Catalogue No.:PA 09 0401015

  • CAS :

    2760759-58-6

  • Molecular Formula : C24H28N2O3

  • Molecular Weight : 392.5

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401016

2-(Aminomethyl)-3,5-di-tert-butylphenol

2-(Aminomethyl)-3,5-di-tert-butylphenol

  • Catalogue No.:PA 09 0401016

  • CAS :

    84210-35-5

  • Molecular Formula : C15H25NO

  • Molecular Weight : 235.37

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401017

N-(4-(tert-Butyl)-3,6-dioxocyclohexa-1,4-dien-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

N-(4-(tert-Butyl)-3,6-dioxocyclohexa-1,4-dien-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401017

  • CAS :

    NA

  • Molecular Formula : C20H18N2O4

  • Molecular Weight : 350.37

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089979

Ivacaftor 13C6

Ivacaftor 13C6

  • Catalogue No.:PA STI 089979

  • CAS :

    NA

  • Molecular Formula : C1813C6H28N2O3

  • Molecular Weight : 398.45

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401018

2,4-Di-tert-butyl-5-nitrophenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

2,4-Di-tert-butyl-5-nitrophenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate

  • Catalogue No.:PA 09 0401018

  • CAS :

    2760759-57-5

  • Molecular Formula : C24H26N2O5

  • Molecular Weight : 422.48

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401019

4-Oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide

4-Oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide

  • Catalogue No.:PA 09 0401019

  • CAS :

    325779-54-2

  • Molecular Formula : C16H12N2O2

  • Molecular Weight : 264.28

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401020

1-Nitrosoquinolin-4(1H)-one

1-Nitrosoquinolin-4(1H)-one

  • Catalogue No.:PA 09 0401020

  • CAS :

    NA

  • Molecular Formula : C9H6N2O2

  • Molecular Weight : 174.16

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Drug Reference Standards & Impurity Synthesis in India
PA 09 0401021

2-Amino-5-(tert-butyl)cyclohexa-2,5-diene-1,4-dione

2-Amino-5-(tert-butyl)cyclohexa-2,5-diene-1,4-dione

  • Catalogue No.:PA 09 0401021

  • CAS :

    35292-13-8

  • Molecular Formula : C10H13NO2

  • Molecular Weight : 179.22

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Drug Reference Standards & Impurity Synthesis in India
PA STI 090098

Deutivacaftor

Deutivacaftor

  • Catalogue No.:PA STI 090098

  • CAS :

    1413431-07-8

  • Molecular Formula : C24H19D9N2O3

  • Molecular Weight : 401.55

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