Ivosidenib and its Impurities
Ivosidenib, sold under the brand name Tibsovo, is a medication for the treatment of acute myeloid leukemia (AML). Reference standards of Ivosidenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(S)-4-(Bis(4-cyanopyridin-2-yl)amino)-5-(((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)(5-fluoropyridin-3-yl)amino)-5-oxopentanoic acid
(S)-4-(Bis(4-cyanopyridin-2-yl)amino)-5-(((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)(5-fluoropyridin-3-yl)amino)-5-oxopentanoic acid
Catalogue No.:PA 09 1051001
CAS :
NA
Molecular Formula : C34H26ClF3N8O4
Molecular Weight : 703.08
3-((S)-1-(4-Carbamoylpyridin-2-yl)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-5-oxopyrrolidine-2-carboxamido)-5-fluoropyridine 1-oxide
3-((S)-1-(4-Carbamoylpyridin-2-yl)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-5-oxopyrrolidine-2-carboxamido)-5-fluoropyridine 1-oxide
Catalogue No.:PA 09 1051002
CAS :
2408269-74-7
Molecular Formula : C28H24ClF3N6O5
Molecular Weight : 616.98
4-Carbamoyl-2-((S)-2-(((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)(5-fluoropyridin-3-yl)carbamoyl)-5-oxopyrrolidin-1-yl)pyridine 1-oxide
4-Carbamoyl-2-((S)-2-(((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)(5-fluoropyridin-3-yl)carbamoyl)-5-oxopyrrolidin-1-yl)pyridine 1-oxide
Catalogue No.:PA 09 1051003
CAS :
NA
Molecular Formula : C28H24ClF3N6O5
Molecular Weight : 616.98
