lamivudine and its Impurities
A drug which is active against both HIV1 and HIV2 virus, Lamivudine is also known as 3TC, is an antiretroviral medication. It is used for the treatment of HIV/AIDS and hepatitis. Lamivudine is an analogue of cytidine. Reference standards of Lamivudine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 03690
CAS :
147126-75-8
Molecular Formula : C18H26FN3O4S
Molecular Weight : 399.48
(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-15N2,13C)-1,3-oxathiolane-2-carboxylate
(2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-15N2,13C)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA STI 058310
CAS :
1322623-13-1
Molecular Formula : C1713CH27N15N2O4S
Molecular Weight : 384.47
Lamivudine Related Compound A ((2RS,5R)-5-(Cytosine-1-yl)-1,3-oxathiolane-2-carboxylic acid) (1357227)
Lamivudine Related Compound A ((2RS,5R)-5-(Cytosine-1-yl)-1,3-oxathiolane-2-carboxylic acid) (1357227)
Catalogue No.:PA USP1357227
CAS :
NA
Molecular Formula : NA
Molecular Weight : NA
1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)-4-((hydroxymethyl)amino)pyrimidin-2(1H)-one
1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)-4-((hydroxymethyl)amino)pyrimidin-2(1H)-one
Catalogue No.:PA 12 03730
CAS :
1904611-13-7
Molecular Formula : C9H13N3O4S
Molecular Weight : 259.28
Phosphonic Acid Mono[[(2R,5S)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] Ester
Phosphonic Acid Mono[[(2R,5S)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] ester
Catalogue No.:PA 12 0031003
CAS :
1128100-81-1
Molecular Formula : C8H12N3O5PS
Molecular Weight : 293.23
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 0031004
CAS :
147126-80-5
Molecular Formula : C18H27N3O4S
Molecular Weight : 381.49
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 0031005
CAS :
200396-21-0
Molecular Formula : C18H27N3O4S
Molecular Weight : 381.49
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 0031010
CAS :
NA
Molecular Formula : C18H27N3O4S
Molecular Weight : 381.49
(2R,2'R,5S,5'S)-5,5'-((Methylenebis(azanediyl))bis(2-oxopyrimidine-4,1(2H)-diyl))bis(1,3-oxathiolane-2-carboxylic acid)
(2R,2'R,5S,5'S)-5,5'-((Methylenebis(azanediyl))bis(2-oxopyrimidine-4,1(2H)-diyl))bis(1,3-oxathiolane-2-carboxylic acid)
Catalogue No.:PA 12 0031012
CAS :
NA
Molecular Formula : C17H18N6O8S2
Molecular Weight : 498.49
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 0031014
CAS :
147027-10-9
Molecular Formula : C18H27N3O4S
Molecular Weight : 381.49
4-Amino-1-((2R,5S)-2-((((1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methoxy)methyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
4-Amino-1-((2R,5S)-2-((((1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methoxy)methyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
Catalogue No.:PA 12 0031017
CAS :
1904611-15-9
Molecular Formula : C17H22N6O6S2
Molecular Weight : 470.52
(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl (2R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl (2R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 0031018
CAS :
1309459-32-2
Molecular Formula : C14H24O4S
Molecular Weight : 288.4
2-Isopropyl-5-methylcyclohexyl 5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
2-Isopropyl-5-methylcyclohexyl 5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 0031019
CAS :
1235039-87-8
Molecular Formula : C18H27N3O4S
Molecular Weight : 381.49
(1S,2R,5S)-2-Isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(1S,2R,5S)-2-Isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
Catalogue No.:PA 12 0031021
CAS :
147126-72-5
Molecular Formula : C18H27N3O4S
Molecular Weight : 381.49
