Lappaconitine and its Impurities

Lappaconitine is a C18-diterpenoid alkaloid extracted from the roots of Aconitum sinomontanum Nakai, a plant traditionally used in Chinese medicine. It is known for its potent analgesic and antiarrhythmic properties and is often formulated as lappaconitine hydrobromide for clinical use. Reference standards of Lappaconitine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.