latanoprost and its Impurities
An ester prodrug, Latanoprost is used to treat ocular hypertension and open angle glaucoma. It helps in treating increased pressure inside the eye. It is released as a free acid inside the cornea. Reference standards of Latanoprost API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
 
	
			                                   
																				(3aR,4R,5R,6aS)-5-((tert-Butyldimethylsilyl)oxy)-4-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one
(3aR,4R,5R,6aS)-5-((tert-Butyldimethylsilyl)oxy)-4-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-one
- Catalogue No.:PA 12 07610 
- CAS : - 1240483-21-9
- Molecular Formula : C30H52O4Si2 
- Molecular Weight : 532.91 
 
	
			                                   
																				(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
- Catalogue No.:PA 12 07620 
- CAS : - 38754-71-1
- Molecular Formula : C21H18O5 
- Molecular Weight : 350.37 
 
	
			                                   
																				(3aR,4R,5R,6aS)-5-((tert-Butyldimethylsilyl)oxy)-4-((S)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-ol
(3aR,4R,5R,6aS)-5-((tert-Butyldimethylsilyl)oxy)-4-((S)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-2-ol
- Catalogue No.:PA 12 07630 
- CAS : - NA
- Molecular Formula : C30H54O4Si2 
- Molecular Weight : 534.93 
 
	
			                                   
																				(Z)-7-((1S,2R,3S,4R)-3-((tert-Butyldimethylsilyl)oxy)-2-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)-4-hydroxycyclopentyl)hept-5-enoic Acid
(Z)-7-((1S,2R,3S,4R)-3-((tert-Butyldimethylsilyl)oxy)-2-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)-4-hydroxycyclopentyl)hept-5-enoic Acid
- Catalogue No.:PA 12 07640 
- CAS : - NA
- Molecular Formula : C35H62O5Si2 
- Molecular Weight : 619.05 
 
	
			                                   
																				Isopropyl (Z)-7-((1R,2R,3R,5S)-3-((tert-butyldimethylsilyl)oxy)-2-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)-5-hydroxycyclopentyl)hept-5-enoate
Isopropyl (Z)-7-((1R,2R,3R,5S)-3-((tert-butyldimethylsilyl)oxy)-2-((R)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpentyl)-5-hydroxycyclopentyl)hept-5-enoate
- Catalogue No.:PA 12 07650 
- CAS : - 474944-22-4
- Molecular Formula : C38H68O5Si2 
- Molecular Weight : 661.13 
 
	
			                                   
																				Latanoprost Related Compound A (Isopropyl (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-ph (1357486)
Latanoprost Related Compound A (Isopropyl (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-ph (1357486)
- Catalogue No.:PA USP1357486 
- CAS : - 913258-34-1
- Molecular Formula : NA 
- Molecular Weight : NA 
 
	
			                                   
																				Latanoprost Related Compound B (Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-ph (1357497)
Latanoprost Related Compound B (Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-ph (1357497)
- Catalogue No.:PA USP1357497 
- CAS : - 145773-22-4
- Molecular Formula : NA 
- Molecular Weight : NA 
 
	
			                                   
																				Latanoprost Related Compound D (Isopropyl (Z)-7-{(1R,2R,3R,5S)-2-[(R)-5-phenyl-3-(triethylsilyloxy) (1357522)
Latanoprost Related Compound D (Isopropyl (Z)-7-{(1R,2R,3R,5S)-2-[(R)-5-phenyl-3-(triethylsilyloxy) (1357522)
- Catalogue No.:PA USP1357522 
- CAS : - 477884-78-9
- Molecular Formula : NA 
- Molecular Weight : NA 
 
	
			                                   
																				Latanoprost Related Compound E ((Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl (1357533)
Latanoprost Related Compound E ((Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl (1357533)
- Catalogue No.:PA USP1357533 
- CAS : - 41639-83-2
- Molecular Formula : NA 
- Molecular Weight : NA 
 
	
			                                   
																				4-(Nitrooxy)butyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate
4-(Nitrooxy)butyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate
- Catalogue No.:PA 12 0071000 
- CAS : - 2099033-64-2
- Molecular Formula : C27H41NO8 
- Molecular Weight : 507.62 
 
	
			                                   
																				(3aR,4R,5R,6aS)-4-((R)-3-Hydroxy-5-phenylpentyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
(3aR,4R,5R,6aS)-4-((R)-3-Hydroxy-5-phenylpentyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
- Catalogue No.:PA 12 0071003 
- CAS : - 145667-74-9
- Molecular Formula : C31H32O5 
- Molecular Weight : 484.59 
 
	
			                                   
																				Isopropyl (Z)-7-((1S,2S,3S,5R)-3,5-dihydroxy-2-((S)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate
Isopropyl (Z)-7-((1S,2S,3S,5R)-3,5-dihydroxy-2-((S)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate
- Catalogue No.:PA 12 0071006 
- CAS : - NA
- Molecular Formula : C26H40O5 
- Molecular Weight : 432.6 

 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
 
 
 
