Leflunomide-impurities | Pharmaffiliates

leflunomide and its Impurities

An immunomodulatory drug, Leflunomide is used to treat rheumatoid arthritis and psoriatic arthritis. An inhibitor of enzyme dihydroorotate dehydrogenase which plays a key role in the synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA. Reference standards of Leflunomide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 31 results for leflunomide Impurities
PA 12 08000

Leflunomide - API

Leflunomide


  • Catalogue No.:PA 12 08000

  • CAS :

    75706-12-6

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

PA 12 08010

Leflunomide - Impurity A

4-(Trifluoromethyl)aniline


  • Catalogue No.:PA 12 08010

  • CAS :

    455-14-1

  • Molecular Formula : C7H6F3N

  • Molecular Weight : 161.12

PA 12 08020

Leflunomide - Impurity B

Teriflunomide


  • Catalogue No.:PA 12 08020

  • CAS :

    163451-81-8

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

PA 12 08030

Leflunomide - Impurity C

5-Methyl-N-[3-(trifluoromethyl)-phenyl]isoxazole-4-carboxamide


  • Catalogue No.:PA 12 08030

  • CAS :

    61643-23-0

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

PA 12 08040

Leflunomide - Impurity D

5-Methylisoxazole-4-carboxylic Acid


  • Catalogue No.:PA 12 08040

  • CAS :

    42831-50-5

  • Molecular Formula : C5H5NO3

  • Molecular Weight : 127.10

PA 12 08050

Leflunomide - Impurity E

3-Methyl-N-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxamide


  • Catalogue No.:PA 12 08050

  • CAS :

    208401-20-1

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

PA 12 08060

Leflunomide - Impurity F

Leflunomide otho-Isomer


  • Catalogue No.:PA 12 08060

  • CAS :

    1403564-06-6

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

PA 12 08070

Leflunomide - Impurity G

5-Methyl-N-(4-methylphenyl)-isoxazole-4-carboxamide


  • Catalogue No.:PA 12 08070

  • CAS :

    724429-16-7

  • Molecular Formula : C12 H12 N2 O2

  • Molecular Weight : 216.24

PA 12 08080

Leflunomide - Impurity H

2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide


  • Catalogue No.:PA 12 08080

  • CAS :

    24522-30-3

  • Molecular Formula : C10H7F3N2O

  • Molecular Weight : 228.17

PA 12 08510

3-Methylisoxazole-4-carboxylic Acid

3-Methylisoxazole-4-carboxylic Acid


  • Catalogue No.:PA 12 08510

  • CAS :

    17153-20-7

  • Molecular Formula : C5H5NO3

  • Molecular Weight : 127.1

PA 12 08520

4-(Fluoromethyl)aniline

4-(Fluoromethyl)aniline


  • Catalogue No.:PA 12 08520

  • CAS :

    61865-29-0

  • Molecular Formula : C7H8FN

  • Molecular Weight : 125.14

PA STI 062330

5-Methylisoxazole-3-carboxylic-d4 Acid

5-Methylisoxazole-3-carboxylic-d4 Acid


  • Catalogue No.:PA STI 062330

  • CAS :

    1267623-84-6

  • Molecular Formula : C5HD4NO3

  • Molecular Weight : 131.12

PA STI 008740

A77 1726-d4

A77 1726-d4


  • Catalogue No.:PA STI 008740

  • CAS :

    1185240-22-5

  • Molecular Formula : C12H5D4F3N2O2

  • Molecular Weight : 274.23

PA STI 049540

5-Hydroxy Leflunomide-d4 (Metabolite M2)

5-Hydroxy Leflunomide-d4 (Metabolite M2)


  • Catalogue No.:PA STI 049540

  • CAS :

    1794789-76-6

  • Molecular Formula : C12H5D4F3N2O3

  • Molecular Weight : 290.23

PA STI 056310

Leflunomide-d4

Leflunomide-d4


  • Catalogue No.:PA STI 056310

  • CAS :

    1189987-23-2

  • Molecular Formula : C12H5D4F3N2O2

  • Molecular Weight : 274.23

PA STI 056311

Lenalidomide-d5

Lenalidomide-d5


  • Catalogue No.:PA STI 056311

  • CAS :

    NA

  • Molecular Formula : C13H8D5N3O3

  • Molecular Weight : 264.29

PA STI 056320

rac Lenalidomide-13C5

rac Lenalidomide-13C5


  • Catalogue No.:PA STI 056320

  • CAS :

    1219332-91-8

  • Molecular Formula : C813C5H13N3O3

  • Molecular Weight : 264.22

PA 12 08530

2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide

2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide


  • Catalogue No.:PA 12 08530

  • CAS :

    108605-62-5

  • Molecular Formula : C12H9F3N2O2

  • Molecular Weight : 270.21

PA IPIPRS 67 13

Leflunomide (IPRS/67/13)-from IPC


  • Catalogue No.:PA IPIPRS 67 13

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA EPY0000487

Leflunomide impurity A (Y0000487)

Leflunomide impurity A (Y0000487)


  • Catalogue No.:PA EPY0000487

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0000654

Leflunomide (Y0000654)

Leflunomide (Y0000654)


  • Catalogue No.:PA EPY0000654

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0000674

Leflunomide for peak identification (Y0000674)

Leflunomide for peak identification (Y0000674)


  • Catalogue No.:PA EPY0000674

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1356960

Leflunomide (1356960)

Leflunomide (1356960)


  • Catalogue No.:PA USP1356960

  • CAS :

    75706-12-6

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1357045

Leflunomide Related Compound A (4-(trifluoromethyl)aniline) (1357045)

Leflunomide Related Compound A (4-(trifluoromethyl)aniline) (1357045)


  • Catalogue No.:PA USP1357045

  • CAS :

    455-14-1

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1357056

Leflunomide Related Compound B (2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide) (1357056)

Leflunomide Related Compound B (2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide) (1357056)


  • Catalogue No.:PA USP1357056

  • CAS :

    108605-62-5

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1357067

Leflunomide Related Compound C (N-(3'-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide) (1357067)

Leflunomide Related Compound C (N-(3'-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide) (1357067)


  • Catalogue No.:PA USP1357067

  • CAS :

    61643-23-0

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 12 08540

3-Methylisoxazole-4-carboxylic Acid Ethyl Ester

3-Methylisoxazole-4-carboxylic Acid Ethyl Ester


  • Catalogue No.:PA 12 08540

  • CAS :

    20328-15-8

  • Molecular Formula : C7H9NO3

  • Molecular Weight : 155.15

PA 12 08550

Ethyl 5-Methylisoxazole-4-carboxylate

Ethyl 5-Methylisoxazole-4-carboxylate


  • Catalogue No.:PA 12 08550

  • CAS :

    51135-73-0

  • Molecular Formula : C7H9NO3

  • Molecular Weight : 155.15

PA 12 0081000

5-Hydroxy leflunomide

5-Hydroxy leflunomide


  • Catalogue No.:PA 12 0081000

  • CAS :

    1058722-46-5

  • Molecular Formula : C12H9F3N2O3

  • Molecular Weight : 286.21

PA 12 0080011

Leflunomide - Impurity A (Hydrochloride)

4-(Trifluoro- methyl)aniline Hydrochloride


  • Catalogue No.:PA 12 0080011

  • CAS :

    90774-69-9

  • Molecular Formula : C7H7ClF3N

  • Molecular Weight : 197.59

PA 12 0081001

 2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide

2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide


  • Catalogue No.:PA 12 0081001

  • CAS :

    419534-37-5

  • Molecular Formula : C10H7F3N2O

  • Molecular Weight : 228.17