Levofloxacin-impurities | Pharmaffiliates

levofloxacin and its Impurities

A broad-spectrum antibiotic, which shows its action against both gram-positive and gram-negative strains. Levofloxacin is a bactericidal antibiotic and used in treating several infections. It is a levo isomer of the racemate ofloxacin. Reference standards of Levofloxacin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 55 results for levofloxacin Impurities
PA 12 13000

Levofloxacin - API Standards

Levofloxacin


  • Catalogue No.:PA 12 13000

  • CAS :

    100986-85-4

  • Molecular Formula : C18H20FN3O4

  • Molecular Weight : 361.37

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PA 12 13010

Levofloxacin - Impurity A (Freebase)

(3R)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1, 4-benzoxazine-6-carboxylic Acid


  • Catalogue No.:PA 12 13010

  • CAS :

    100986-86-5

  • Molecular Formula : C18H20FN3O4

  • Molecular Weight : 361.37

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PA 12 13020

Levofloxacin - Impurity B

(3S)-9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4- benzoxazine-6-carboxylic Acid


  • Catalogue No.:PA 12 13020

  • CAS :

    117707-40-1

  • Molecular Formula : C17H18FN3O4

  • Molecular Weight : 347.34

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PA 12 13030

Levofloxacin - Impurity C

Levofloxacin N-Oxide


  • Catalogue No.:PA 12 13030

  • CAS :

    117678-38-3

  • Molecular Formula : C18H20FN3O5

  • Molecular Weight : 377.38

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PA 12 13040

Levofloxacin - Impurity D

(3S)-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4- benzoxazine-6-carboxylic Acid


  • Catalogue No.:PA 12 13040

  • CAS :

    117620-85-6

  • Molecular Formula : C18H21N3O4

  • Molecular Weight : 343.38

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PA 12 13050

Levofloxacin - Impurity E

(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one


  • Catalogue No.:PA 12 13050

  • CAS :

    178964-53-9

  • Molecular Formula : C17H20FN3O2

  • Molecular Weight : 317.36

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PA 12 13060

Levofloxacin - Impurity F

(3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid


  • Catalogue No.:PA 12 13060

  • CAS :

    100986-89-8

  • Molecular Formula : C13H9F2NO4

  • Molecular Weight : 281.21

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PA 12 13540

Levofloxacin - Impurity I

9-Piperazine Levofloxacin


  • Catalogue No.:PA 12 13540

  • CAS :

    178912-62-4

  • Molecular Formula : C18H20FN3O4

  • Molecular Weight : 361.38

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PA 12 13560

N,N'-Desethylene Levofloxacin Hydrochloride

N,N'-Desethylene Levofloxacin Hydrochloride


  • Catalogue No.:PA 12 13560

  • CAS :

    1346603-62-0

  • Molecular Formula : C16H19ClFN3O4

  • Molecular Weight : 371.79

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PA 12 13570

Levofloxacin Diamine Hydrochloride Salt

Levofloxacin Diamine Hydrochloride Salt


  • Catalogue No.:PA 12 13570

  • CAS :

    1797099-76-3

  • Molecular Formula : C15H17ClFN3O4

  • Molecular Weight : 357.76

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PA 12 13580

(3S)-10-(4-Ethyl-1-piperazinyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid

(3S)-10-(4-Ethyl-1-piperazinyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid


  • Catalogue No.:PA 12 13580

  • CAS :

    106939-30-4

  • Molecular Formula : C19H22FN3O4

  • Molecular Weight : 375.39

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PA 12 13650

Levofloxacin Diamine

Levofloxacin Diamine


  • Catalogue No.:PA 12 13650

  • CAS :

    1797510-34-9

  • Molecular Formula : C15H16FN3O4

  • Molecular Weight : 321.3

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PA 12 13051

Levofloxacin - Impurity E (Hydrochloride Salt)

(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one Hydrochloride Salt


  • Catalogue No.:PA 12 13051

  • CAS :

    NA

  • Molecular Formula : C17H21ClFN3O2

  • Molecular Weight : 353.82

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PA 12 13510

N,N'-Desethylene-N,N'-diformyl Levofloxacin

N,N'-Desethylene-N,N'-diformyl Levofloxacin


  • Catalogue No.:PA 12 13510

  • CAS :

    151377-74-1

  • Molecular Formula : C18H18FN3O6

  • Molecular Weight : 391.35

PA 12 13520

Levofloxacin - Impurity G

N,N'-Desethylene Levofloxacin


  • Catalogue No.:PA 12 13520

  • CAS :

    151250-76-9

  • Molecular Formula : C16H18FN3O4

  • Molecular Weight : 335.33

PA 12 13530

Levofloxacin Ethyl Ester

Levofloxacin Ethyl Ester


  • Catalogue No.:PA 12 13530

  • CAS :

    177472-30-9

  • Molecular Formula : C20H24FN3O4

  • Molecular Weight : 389.42

PA 12 13550

N-tert-Butoxycarbonyl Desmethyl Levofloxacin

N-tert-Butoxycarbonyl Desmethyl Levofloxacin


  • Catalogue No.:PA 12 13550

  • CAS :

    1330277-19-4

  • Molecular Formula : C22H26FN3O6

  • Molecular Weight : 447.46

PA 12 13590

Levofloxacin Chloromethyl Ester

Levofloxacin Chloromethyl Ester


  • Catalogue No.:PA 12 13590

  • CAS :

    2206825-95-6

  • Molecular Formula : C19H21ClFN3O4

  • Molecular Weight : 409.84

PA 12 13600

(3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester

(3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester


  • Catalogue No.:PA 12 13600

  • CAS :

    106939-34-8

  • Molecular Formula : C15H13F2NO4

  • Molecular Weight : 309.26

PA 12 13610

(S)-7,8-Difluoro-3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine Sulfate

(S)-7,8-Difluoro-3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine Sulfate


  • Catalogue No.:PA 12 13610

  • CAS :

    NA

  • Molecular Formula : C9H11F2NO5S

  • Molecular Weight : 283.25

PA 12 13620

Ethyl 3-(N,N-dimethyl amino)-2-(2,3,4,5-tetrafluorobenzoyl) Acrylate

Ethyl 3-(N,N-dimethyl amino)-2-(2,3,4,5-tetrafluorobenzoyl) Acrylate


  • Catalogue No.:PA 12 13620

  • CAS :

    138998-47-7

  • Molecular Formula : C14H13F4NO3

  • Molecular Weight : 319.25

PA 12 13630

Ethyl (2Z)-(3-(1-hydroxy-2-propanyl)amino)-2-(2,3,4,5-tetrafluorobenzoyl) Acrylate

Ethyl (2Z)-(3-(1-hydroxy-2-propanyl)amino)-2-(2,3,4,5-tetrafluorobenzoyl) Acrylate


  • Catalogue No.:PA 12 13630

  • CAS :

    NA

  • Molecular Formula : C15H15F4NO4

  • Molecular Weight : 349.28

PA 12 13640

(Z)-Ethyl 3-(dimethylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate

(Z)-Ethyl 3-(dimethylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate


  • Catalogue No.:PA 12 13640

  • CAS :

    1363407-28-6

  • Molecular Formula : C15H16F3NO4

  • Molecular Weight : 331.29

PA STI 025020

Defluoro Levofloxacin-d3

Defluoro Levofloxacin-d3


  • Catalogue No.:PA STI 025020

  • CAS :

    1329836-14-7

  • Molecular Formula : C18H18D3N3O4

  • Molecular Weight : 346.40

PA STI 027380

N,N'-Desethylene-N,N'-diformyl Levofloxacin-d3

N,N'-Desethylene-N,N'-diformyl Levofloxacin-d3


  • Catalogue No.:PA STI 027380

  • CAS :

    1346598-04-6

  • Molecular Formula : C18H15D3FN3O6

  • Molecular Weight : 394.37

PA STI 028400

Desmethyl Levofloxacin-d8 Hydrochloride

Desmethyl Levofloxacin-d8 Hydrochloride


  • Catalogue No.:PA STI 028400

  • CAS :

    1217677-38-7

  • Molecular Formula : C17H11D8ClFN3O4

  • Molecular Weight : 391.85

PA STI 056480

Levofloxacin-d8

Levofloxacin-d8


  • Catalogue No.:PA STI 056480

  • CAS :

    1217716-71-6

  • Molecular Formula : C18H12D8FN3O4

  • Molecular Weight : 369.42

PA STI 056481

Levofloxacin-d3

Levofloxacin-d3


  • Catalogue No.:PA STI 056481

  • CAS :

    NA

  • Molecular Formula : C18H17D3FN3O4

  • Molecular Weight : 364.39

PA STI 056490

Levofloxacin-d8 Acyl-β-D-glucuronide

Levofloxacin-d8 Acyl-β-D-glucuronide


  • Catalogue No.:PA STI 056490

  • CAS :

    NA

  • Molecular Formula : C24H20D8FN3O10

  • Molecular Weight : 545.54

PAI 12 003010

Potassium (S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Potassium (S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate


  • Catalogue No.:PAI 12 003010

  • CAS :

    NA

  • Molecular Formula : C18H19FKN3O4

  • Molecular Weight : 399.50

PA 12 13021

Levofloxacin - Impurity B (Hydrochloride Salt)

Desmethyl Levofloxacin Hydrochloride


  • Catalogue No.:PA 12 13021

  • CAS :

    2254176-11-7

  • Molecular Formula : C17H19ClFN3O4

  • Molecular Weight : 383.8

PA 12 13080

Levofloxacin - Impurity H

Ethyl (3R)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate


  • Catalogue No.:PA 12 13080

  • CAS :

    NA

  • Molecular Formula : C20H24FN3O4

  • Molecular Weight : 389.43

PA 12 13660

9-fluoro-10-(4-(2-hydroxyethyl)-4-methylpiperazin-1-ium-1-yl)-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

9-fluoro-10-(4-(2-hydroxyethyl)-4-methylpiperazin-1-ium-1-yl)-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate


  • Catalogue No.:PA 12 13660

  • CAS :

    NA

  • Molecular Formula : C20H24FN3O5

  • Molecular Weight : 405.43

PA 12 13680

(3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-Piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-Benzoxazine-6-Varboxylic Acid

(3R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-Piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-Benzoxazine-6-Varboxylic Acid


  • Catalogue No.:PA 12 13680

  • CAS :

    117678-37-2

  • Molecular Formula : C18H20FN3O5

  • Molecular Weight : 377.37

PA 12 13670

2,3,5-trifluoro-4-(4-methyl-1-piperazinyl)-β-oxo-benzenepropanoic Acid

2,3,5-trifluoro-4-(4-methyl-1-piperazinyl)-β-oxo-benzenepropanoic Acid


  • Catalogue No.:PA 12 13670

  • CAS :

    108860-30-6

  • Molecular Formula : C16H19F3N2O3

  • Molecular Weight : 344.33

PA 12 13690

(3S)-9,10-difluoro-3-methyl-7-oxo-2,3,6,7-tetrahydro-5H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid

(3S)-9,10-difluoro-3-methyl-7-oxo-2,3,6,7-tetrahydro-5H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid


  • Catalogue No.:PA 12 13690

  • CAS :

    1026952-91-9

  • Molecular Formula : C13H11F2NO4

  • Molecular Weight : 283.23

PA 12 0131000

Levofloxacin Hydroxy Acid

Levofloxacin Hydroxy Acid


  • Catalogue No.:PA 12 0131000

  • CAS :

    1036016-10-0

  • Molecular Formula : C18H21F2N3O4

  • Molecular Weight : 381.38

PA 12 0131001

5-Methyl-2-nitrophenol

5-Methyl-2-nitrophenol


  • Catalogue No.:PA 12 0131001

  • CAS :

    700-38-9

  • Molecular Formula : C7H7NO3

  • Molecular Weight : 153.14

PA 12 0131002

(3S)-10-Fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid

(3S)-10-Fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid


  • Catalogue No.:PA 12 0131002

  • CAS :

    117620-84-5

  • Molecular Formula : C13H10FNO4

  • Molecular Weight : 263.22

PA 12 0131003

2,3,4,5-Tetrafluoro-α-[[[(1S)-2-hydroxy-1-methylethyl]amino]methylene]-β-oxo-benzenepropanoic Acid Ethyl Ester

2,3,4,5-Tetrafluoro-α-[[[(1S)-2-hydroxy-1-methylethyl]amino]methylene]-β-oxo-benzenepropanoic Acid Ethyl Ester


  • Catalogue No.:PA 12 0131003

  • CAS :

    110548-02-2

  • Molecular Formula : C15H15F4NO4

  • Molecular Weight : 349.28

PAI 12 003011

Ethyl (S)-8-amino-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl (S)-8-amino-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate


  • Catalogue No.:PAI 12 003011

  • CAS :

    2130840-90-1

  • Molecular Formula : C20H25FN4O4

  • Molecular Weight : 404.44

PAI 12 003012

Ethyl (S)-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl (S)-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate


  • Catalogue No.:PAI 12 003012

  • CAS :

    2130840-92-3

  • Molecular Formula : C20H24FN3O4

  • Molecular Weight : 389.43

PAI 12 003013

Ethyl (3S)-9,10-difluoro-2,3-dihydro-3-methyl-8-nitro-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate

Ethyl (3S)-9,10-difluoro-2,3-dihydro-3-methyl-8-nitro-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate


  • Catalogue No.:PAI 12 003013

  • CAS :

    1012310-27-8

  • Molecular Formula : C15H12F2N2O6

  • Molecular Weight : 354.27

PAI 12 003014

Ethyl (S)-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-8-nitro-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl (S)-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-8-nitro-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate


  • Catalogue No.:PAI 12 003014

  • CAS :

    2130840-88-7

  • Molecular Formula : C20H23FN4O6

  • Molecular Weight : 434.42

PA 12 0131004

Ethyl (E)-3-(dimethylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate

Ethyl (E)-3-(dimethylamino)-2-(2,4,5-trifluoro-3-methoxybenzoyl)acrylate


  • Catalogue No.:PA 12 0131004

  • CAS :

    121577-35-3

  • Molecular Formula : C15H16F3NO4

  • Molecular Weight : 331.29

PAI 12 003015

(S)-3-Methyl-10-(4-methylpiperazin-1-yl)-9-(methylthio)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid

(S)-3-Methyl-10-(4-methylpiperazin-1-yl)-9-(methylthio)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid


  • Catalogue No.:PAI 12 003015

  • CAS :

    2574301-93-0

  • Molecular Formula : C19H23N3O4S

  • Molecular Weight : 389.47

PA STI 089116

Levofloxacin-13C-D3

Levofloxacin-13C-D3


  • Catalogue No.:PA STI 089116

  • CAS :

    1261398-33-7

  • Molecular Formula : C1713CH17D3FN3O4

  • Molecular Weight : 365.38

PA 12 0131005

(S)-9-Fluoro-3-methyl-10-(4-nitrosopiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid

(S)-9-Fluoro-3-methyl-10-(4-nitrosopiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid


  • Catalogue No.:PA 12 0131005

  • CAS :

    1152314-62-9

  • Molecular Formula : C17H17FN4O5

  • Molecular Weight : 376.34

PA 12 0131006

(S)-10-((2-Aminoethyl)(nitroso)amino)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Hydrochloride

(S)-10-((2-Aminoethyl)(nitroso)amino)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Hydrochloride


  • Catalogue No.:PA 12 0131006

  • CAS :

    NA

  • Molecular Formula : C15H16ClFN4O5

  • Molecular Weight : 386.76

PA IMPL028

Levofloxacin Impurity A (IMPL028)

Levofloxacin Impurity A (IMPL028)


  • Catalogue No.:PA IMPL028

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PAI 12 003016

Ethyl (S)-8-bromo-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Ethyl (S)-8-bromo-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate


  • Catalogue No.:PAI 12 003016

  • CAS :

    NA

  • Molecular Formula : C20H23BrFN3O4

  • Molecular Weight : 468.32

PA 12 0131007

(R)-9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid

(R)-9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid


  • Catalogue No.:PA 12 0131007

  • CAS :

    117707-39-8

  • Molecular Formula : C17H18FN3O4

  • Molecular Weight : 347.35

PA STI 089736

N-Nitroso Desmethyl Levofloxacin D8

N-Nitroso Desmethyl Levofloxacin D8


  • Catalogue No.:PA STI 089736

  • CAS :

    NA

  • Molecular Formula : C17H9D8FN4O5

  • Molecular Weight : 384.39

PA 12 0131008

(S)-9-Fluoro-3-methyl-10-((2-(methyl(nitroso)amino)ethyl)(nitroso)amino)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid

(S)-9-Fluoro-3-methyl-10-((2-(methyl(nitroso)amino)ethyl)(nitroso)amino)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid


  • Catalogue No.:PA 12 0131008

  • CAS :

    NA

  • Molecular Formula : C16H16FN5O6

  • Molecular Weight : 393.33

PA BSC 01312512

(3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester (BSC)

(3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester


  • Catalogue No.:PA BSC 01312512

  • CAS :

    106939-34-8

  • Molecular Formula : C15H13F2NO4

  • Molecular Weight : 309.26