lifitegrast and its Impurities

lifitegrast is used to treat the signs and symptoms of dry eye disease. It is an FDA approved drug indicated. Lifitegrast reduces inflammation by inhibiting inflammatory cell binding. Reference standards of Lifitegrast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 40 results for lifitegrast Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 39 04000

Lifitegrast

Lifitegrast

  • Catalogue No.:PA 39 04000

  • CAS :

    1025967-78-5

  • Molecular Formula : C29H24Cl2N2O7S

  • Molecular Weight : 615.48

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Drug Reference Standards & Impurity Synthesis in India
PA 39 04510

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid Hydrochloride

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid Hydrochloride

  • Catalogue No.:PA 39 04510

  • CAS :

    2271054-95-4

  • Molecular Formula : C20H21Cl3N2O5S

  • Molecular Weight : 507.81

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Drug Reference Standards & Impurity Synthesis in India
PA 39 04520

(S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 04520

  • CAS :

    NA

  • Molecular Formula : C22H22Cl2N2O6S

  • Molecular Weight : 513.39

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Drug Reference Standards & Impurity Synthesis in India
PA 39 04530

Benzofuran-6-carboxylic Acid

Benzofuran-6-carboxylic Acid

  • Catalogue No.:PA 39 04530

  • CAS :

    77095-51-3

  • Molecular Formula : C9H6O3

  • Molecular Weight : 162.14

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Drug Reference Standards & Impurity Synthesis in India
PA 39 04540

(S)-2-(2-(Benzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(2-(Benzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 04540

  • CAS :

    2295862-00-7

  • Molecular Formula : C29H26N2O7S

  • Molecular Weight : 546.59

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Drug Reference Standards & Impurity Synthesis in India
PA 39 04550

Ethyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Ethyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 04550

  • CAS :

    2295862-24-5

  • Molecular Formula : C31H28Cl2N2O7S

  • Molecular Weight : 643.53

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Drug Reference Standards & Impurity Synthesis in India
PA 39 04560

Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 04560

  • CAS :

    1194550-67-8

  • Molecular Formula : C36H30Cl2N2O7S

  • Molecular Weight : 705.6

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Drug Reference Standards & Impurity Synthesis in India
PA 39 04570

Methyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Methyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 04570

  • CAS :

    2295862-29-0

  • Molecular Formula : C30H26Cl2N2O7S

  • Molecular Weight : 629.51

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041000

Lifitegrast R-Isomer

Lifitegrast R-Isomer

  • Catalogue No.:PA 39 0041000

  • CAS :

    2271299-08-0

  • Molecular Formula : C29H24Cl2N2O7S

  • Molecular Weight : 615.48

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041001

(S)-2-(2-(Benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041001

  • CAS :

    2322380-15-2

  • Molecular Formula : C29H25ClN2O7S

  • Molecular Weight : 581.04

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041002

(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041002

  • CAS :

    2322380-18-5

  • Molecular Formula : C29H25ClN2O7S

  • Molecular Weight : 581.04

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041003

5-Bromo-2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

5-Bromo-2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

  • Catalogue No.:PA 39 0041003

  • CAS :

    2832127-60-1

  • Molecular Formula : C15H17BrClNO4

  • Molecular Weight : 390.66

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041004

7-Bromo-2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

7-Bromo-2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

  • Catalogue No.:PA 39 0041004

  • CAS :

    2832100-74-8

  • Molecular Formula : C15H17BrClNO4

  • Molecular Weight : 390.66

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041005

(S)-2-(2-(Benzofuran-6-carbonyl)-5-bromo-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5-bromo-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041005

  • CAS :

    NA

  • Molecular Formula : C31H28BrClN2O5S

  • Molecular Weight : 655.99

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041006

(S)-2-(2-(Benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041006

  • CAS :

    NA

  • Molecular Formula : C31H28BrClN2O5S

  • Molecular Weight : 655.99

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041007

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2-dihydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2-dihydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041007

  • CAS :

    NA

  • Molecular Formula : C29H22Cl2N2O7S

  • Molecular Weight : 613.46

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041008

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041008

  • CAS :

    NA

  • Molecular Formula : C29H22Cl2N2O8S

  • Molecular Weight : 629.46

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041009

(S)-2-(2-(Benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid

  • Catalogue No.:PA 39 0041009

  • CAS :

    NA

  • Molecular Formula : C28H21BrCl2N2O5

  • Molecular Weight : 616.29

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041010

(S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3(methylsulfonyl)phenyl)propanoicacid

(S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3(methylsulfonyl)phenyl)propanoicacid

  • Catalogue No.:PA 39 0041010

  • CAS :

    2641788-18-1

  • Molecular Formula : C39H35Cl2N3O10S2

  • Molecular Weight : 840.74

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041011

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride

  • Catalogue No.:PA 39 0041011

  • CAS :

    1289646-93-0

  • Molecular Formula : C10H10Cl3NO2

  • Molecular Weight : 282.55

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041012

2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

  • Catalogue No.:PA 39 0041012

  • CAS :

    2129597-34-6

  • Molecular Formula : C19H13Cl2NO4

  • Molecular Weight : 390.22

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041013

tert-Butyl (S)-6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate

tert-Butyl (S)-6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate

  • Catalogue No.:PA 39 0041013

  • CAS :

    1194550-61-2

  • Molecular Formula : C32H34Cl2N2O7S

  • Molecular Weight : 661.59

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041014

Benzyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Benzyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 0041014

  • CAS :

    1194864-18-0

  • Molecular Formula : C27H26Cl2N2O5S

  • Molecular Weight : 561.47

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041015

(S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041015

  • CAS :

    1270093-99-6

  • Molecular Formula : C10H13NO4S

  • Molecular Weight : 243.28

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041016

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041016

  • CAS :

    851785-70-1

  • Molecular Formula : C20H20Cl2N2O5S

  • Molecular Weight : 471.35

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PA 39 0041017

5,7-Dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

5,7-Dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

  • Catalogue No.:PA 39 0041017

  • CAS :

    NA

  • Molecular Formula : C10H8Cl2N2O3

  • Molecular Weight : 275.09

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041018

tert-Butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

tert-Butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 0041018

  • CAS :

    2414639-05-5

  • Molecular Formula : C33H32Cl2N2O7S

  • Molecular Weight : 671.59

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041019

(2S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-hydroxy-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(2S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-hydroxy-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041019

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041020

(2S)-2-(5,7-Dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(2S)-2-(5,7-Dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041020

  • CAS :

    NA

  • Molecular Formula : C29H26Cl2N2O9S

  • Molecular Weight : 649.49

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041021

(2S)-2-(5,7-Dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(2S)-2-(5,7-Dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041021

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041022

Methyl 3-hydroxy-4-iodobenzoate

Methyl 3-hydroxy-4-iodobenzoate

  • Catalogue No.:PA 39 0041022

  • CAS :

    157942-12-6

  • Molecular Formula : C8H7IO3

  • Molecular Weight : 278.05

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041023

(S)-2-(5,7-Dichloro-2-(4-formyl-3-hydroxybenzoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(5,7-Dichloro-2-(4-formyl-3-hydroxybenzoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041023

  • CAS :

    NA

  • Molecular Formula : C28H24Cl2N2O8S

  • Molecular Weight : 619.47

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041024

Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate Hydrochloride

Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate Hydrochloride

  • Catalogue No.:PA 39 0041024

  • CAS :

    2049127-84-4

  • Molecular Formula : C11H16ClNO4S

  • Molecular Weight : 293.76

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041025

3,5-Dichloro-N-(2-hydroxyethyl)benzamide

3,5-Dichloro-N-(2-hydroxyethyl)benzamide

  • Catalogue No.:PA 39 0041025

  • CAS :

    344307-65-9

  • Molecular Formula : C9H9Cl2NO2

  • Molecular Weight : 234.08

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PA 39 0041026

2-((3,5-Dichlorobenzyl)amino)ethan-1-ol

2-((3,5-Dichlorobenzyl)amino)ethan-1-ol

  • Catalogue No.:PA 39 0041026

  • CAS :

    1183137-67-8

  • Molecular Formula : C9H11Cl2NO

  • Molecular Weight : 220.09

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041027

5,7-Dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline

5,7-Dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline

  • Catalogue No.:PA 39 0041027

  • CAS :

    1289646-72-5

  • Molecular Formula : C28H23Cl2N

  • Molecular Weight : 444.4

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Drug Reference Standards & Impurity Synthesis in India
PA 39 0041028

Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate

Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 0041028

  • CAS :

    1213360-49-6

  • Molecular Formula : C11H15NO4S

  • Molecular Weight : 257.3

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PA 39 0041029

2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid

2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041029

  • CAS :

    1270324-69-0

  • Molecular Formula : C10H13NO4S

  • Molecular Weight : 243.28

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PA BSC 0043901181

Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate (BSC)

Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate (BSC)

  • Catalogue No.:PA BSC 0043901181

  • CAS :

    1213360-49-6

  • Molecular Formula : C11H15NO4S

  • Molecular Weight : 257.3

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PA 39 0041030

2-(Benzofuran-6-carbonyl)-6-(((S)-1-carboxy-2-(3-(methylsulfonyl)phenyl)ethyl)carbamoyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline 2-oxide

2-(Benzofuran-6-carbonyl)-6-(((S)-1-carboxy-2-(3-(methylsulfonyl)phenyl)ethyl)carbamoyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline 2-oxide

  • Catalogue No.:PA 39 0041030

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

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