lifitegrast and its Impurities

lifitegrast is used to treat the signs and symptoms of dry eye disease. It is an FDA approved drug indicated. Lifitegrast reduces inflammation by inhibiting inflammatory cell binding. Reference standards of Lifitegrast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 32 results for lifitegrast Impurities
PA 39 04000

Lifitegrast

Lifitegrast

  • Catalogue No.:PA 39 04000

  • CAS :

    1025967-78-5

  • Molecular Formula : C29H24Cl2N2O7S

  • Molecular Weight : 615.48

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PA 39 04510

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid Hydrochloride

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid Hydrochloride

  • Catalogue No.:PA 39 04510

  • CAS :

    2271054-95-4

  • Molecular Formula : C20H21Cl3N2O5S

  • Molecular Weight : 507.81

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PA 39 04520

(S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 04520

  • CAS :

    NA

  • Molecular Formula : C22H22Cl2N2O6S

  • Molecular Weight : 513.39

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PA 39 04530

Benzofuran-6-carboxylic Acid

Benzofuran-6-carboxylic Acid

  • Catalogue No.:PA 39 04530

  • CAS :

    77095-51-3

  • Molecular Formula : C9H6O3

  • Molecular Weight : 162.14

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PA 39 04540

(S)-2-(2-(Benzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(2-(Benzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 04540

  • CAS :

    2295862-00-7

  • Molecular Formula : C29H26N2O7S

  • Molecular Weight : 546.59

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PA 39 04550

Ethyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Ethyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 04550

  • CAS :

    2295862-24-5

  • Molecular Formula : C31H28Cl2N2O7S

  • Molecular Weight : 643.53

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PA 39 04560

Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 04560

  • CAS :

    1194550-67-8

  • Molecular Formula : C36H30Cl2N2O7S

  • Molecular Weight : 705.6

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PA 39 04570

Methyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Methyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 04570

  • CAS :

    2295862-29-0

  • Molecular Formula : C30H26Cl2N2O7S

  • Molecular Weight : 629.51

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PA 39 0041000

Lifitegrast R-Isomer

Lifitegrast R-Isomer

  • Catalogue No.:PA 39 0041000

  • CAS :

    2271299-08-0

  • Molecular Formula : C29H24Cl2N2O7S

  • Molecular Weight : 615.48

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PA 39 0041001

(S)-2-(2-(Benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041001

  • CAS :

    2322380-15-2

  • Molecular Formula : C29H25ClN2O7S

  • Molecular Weight : 581.04

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PA 39 0041002

(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(benzofuran-6-carbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041002

  • CAS :

    2322380-18-5

  • Molecular Formula : C29H25ClN2O7S

  • Molecular Weight : 581.04

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PA 39 0041003

5-Bromo-2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

5-Bromo-2-(tert-butoxycarbonyl)-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

  • Catalogue No.:PA 39 0041003

  • CAS :

    2832127-60-1

  • Molecular Formula : C15H17BrClNO4

  • Molecular Weight : 390.66

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PA 39 0041004

7-Bromo-2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

7-Bromo-2-(tert-butoxycarbonyl)-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid

  • Catalogue No.:PA 39 0041004

  • CAS :

    2832100-74-8

  • Molecular Formula : C15H17BrClNO4

  • Molecular Weight : 390.66

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PA 39 0041005

(S)-2-(2-(Benzofuran-6-carbonyl)-5-bromo-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5-bromo-7-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041005

  • CAS :

    NA

  • Molecular Formula : C31H28BrClN2O5S

  • Molecular Weight : 655.99

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PA 39 0041006

(S)-2-(2-(Benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methyldimethylene-l6-sulfanyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041006

  • CAS :

    NA

  • Molecular Formula : C31H28BrClN2O5S

  • Molecular Weight : 655.99

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PA 39 0041007

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2-dihydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2-dihydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041007

  • CAS :

    NA

  • Molecular Formula : C29H22Cl2N2O7S

  • Molecular Weight : 613.46

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PA 39 0041008

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid

  • Catalogue No.:PA 39 0041008

  • CAS :

    NA

  • Molecular Formula : C29H22Cl2N2O8S

  • Molecular Weight : 629.46

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PA 39 0041009

(S)-2-(2-(Benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid

(S)-2-(2-(Benzofuran-6-carbonyl )-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid

  • Catalogue No.:PA 39 0041009

  • CAS :

    NA

  • Molecular Formula : C28H21BrCl2N2O5

  • Molecular Weight : 616.29

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PA 39 0041010

(S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3(methylsulfonyl)phenyl)propanoicacid

(S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3(methylsulfonyl)phenyl)propanoicacid

  • Catalogue No.:PA 39 0041010

  • CAS :

    2641788-18-1

  • Molecular Formula : C39H35Cl2N3O10S2

  • Molecular Weight : 840.74

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PA 39 0041011

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride

  • Catalogue No.:PA 39 0041011

  • CAS :

    1289646-93-0

  • Molecular Formula : C10H10Cl3NO2

  • Molecular Weight : 282.55

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PA 39 0041012

2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

  • Catalogue No.:PA 39 0041012

  • CAS :

    2129597-34-6

  • Molecular Formula : C19H13Cl2NO4

  • Molecular Weight : 390.22

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PA 39 0041013

tert-Butyl (S)-6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate

tert-Butyl (S)-6-((1-(benzyloxy)-3-(3-(methylsulfonyl)phenyl)-1-oxopropan-2-yl)carbamoyl)-5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylate

  • Catalogue No.:PA 39 0041013

  • CAS :

    1194550-61-2

  • Molecular Formula : C32H34Cl2N2O7S

  • Molecular Weight : 661.59

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PA 39 0041014

Benzyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

Benzyl (S)-2-(5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 0041014

  • CAS :

    1194864-18-0

  • Molecular Formula : C27H26Cl2N2O5S

  • Molecular Weight : 561.47

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PA 39 0041015

(S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041015

  • CAS :

    1270093-99-6

  • Molecular Formula : C10H13NO4S

  • Molecular Weight : 243.28

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PA 39 0041016

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041016

  • CAS :

    851785-70-1

  • Molecular Formula : C20H20Cl2N2O5S

  • Molecular Weight : 471.35

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PA 39 0041017

5,7-Dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

5,7-Dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid

  • Catalogue No.:PA 39 0041017

  • CAS :

    NA

  • Molecular Formula : C10H8Cl2N2O3

  • Molecular Weight : 275.09

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PA 39 0041018

tert-Butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

tert-Butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate

  • Catalogue No.:PA 39 0041018

  • CAS :

    2414639-05-5

  • Molecular Formula : C33H32Cl2N2O7S

  • Molecular Weight : 671.59

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PA 39 0041019

(2S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-hydroxy-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(2S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-hydroxy-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041019

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

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PA 39 0041020

(2S)-2-(5,7-Dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(2S)-2-(5,7-Dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041020

  • CAS :

    NA

  • Molecular Formula : C29H26Cl2N2O9S

  • Molecular Weight : 649.49

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PA 39 0041021

(2S)-2-(5,7-Dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(2S)-2-(5,7-Dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041021

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

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PA 39 0041022

Methyl 3-hydroxy-4-iodobenzoate

Methyl 3-hydroxy-4-iodobenzoate

  • Catalogue No.:PA 39 0041022

  • CAS :

    157942-12-6

  • Molecular Formula : C8H7IO3

  • Molecular Weight : 278.05

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PA 39 0041023

(S)-2-(5,7-Dichloro-2-(4-formyl-3-hydroxybenzoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

(S)-2-(5,7-Dichloro-2-(4-formyl-3-hydroxybenzoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid

  • Catalogue No.:PA 39 0041023

  • CAS :

    NA

  • Molecular Formula : C28H24Cl2N2O8S

  • Molecular Weight : 619.47

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CPHI INDIA- 28, 30 November