lubiprostone and its Impurities

Lubiprostone used in the management of idiopathic chronic constipation. It is sold under the trade name Amitiza. Reference standards of Lubiprostone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 32 results for lubiprostone Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 12 87000

Lubiprostone

Lubiprostone

  • Catalogue No.:PA 12 87000

  • CAS :

    136790-76-6

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.46

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Drug Reference Standards & Impurity Synthesis in India
PA 12 87510

7-((2S,4aS,5S,7aS)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic Acid

7-((2S,4aS,5S,7aS)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic Acid

  • Catalogue No.:PA 12 87510

  • CAS :

    2743427-14-5

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.46

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Drug Reference Standards & Impurity Synthesis in India
PA 12 87520

Lubiprostone (Mixture of Tautomeric Isomers)

Lubiprostone (Mixture of Tautomeric Isomers)

  • Catalogue No.:PA 12 87520

  • CAS :

    333963-40-9(ring-closed),136790-76-6(ring-opened)

  • Molecular Formula : C40H64F4O10

  • Molecular Weight : 780.94

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Drug Reference Standards & Impurity Synthesis in India
PA 12 87540

7-((1S,2R,5R,8S)-2-(1,1-Difluoropentyl)-2,8-dihydroxy-7-oxobicyclo[3.2.1]octan-6-yl)heptanoic Acid

7-((1S,2R,5R,8S)-2-(1,1-Difluoropentyl)-2,8-dihydroxy-7-oxobicyclo[3.2.1]octan-6-yl)heptanoic Acid

  • Catalogue No.:PA 12 87540

  • CAS :

    NA

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.46

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Drug Reference Standards & Impurity Synthesis in India
PA STI 049600

15-Hydroxy Lubiprostone Dicyclohexylammonium Salt-d7

15-Hydroxy Lubiprostone Dicyclohexylammonium Salt-d7

  • Catalogue No.:PA STI 049600

  • CAS :

    NA

  • Molecular Formula : C32H50D7F2NO5

  • Molecular Weight : 580.84

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Drug Reference Standards & Impurity Synthesis in India
PA STI 049610

15-Hydroxy Lubiprostone Phenylmethyl Ester-d7 (Mixture of Diastereomers)

15-Hydroxy Lubiprostone Phenylmethyl Ester-d7 (Mixture of Diastereomers)

  • Catalogue No.:PA STI 049610

  • CAS :

    1346597-35-0

  • Molecular Formula : C27H33D7F2O5

  • Molecular Weight : 489.64

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Drug Reference Standards & Impurity Synthesis in India
PA STI 057250

Lubiprostone-d9

Lubiprostone-d9

  • Catalogue No.:PA STI 057250

  • CAS :

    1134188-25-2

  • Molecular Formula : C20H23D9F2O5

  • Molecular Weight : 399.52

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Drug Reference Standards & Impurity Synthesis in India
PA STI 057260

Lubiprostone-d7

Lubiprostone-d7

  • Catalogue No.:PA STI 057260

  • CAS :

    1217675-13-2

  • Molecular Formula : C20H25D7F2O5

  • Molecular Weight : 397.51

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Drug Reference Standards & Impurity Synthesis in India
PA STI 082200

11-O-Tetrahydropyranyl-15-O-tert-butyldimethylsilyl-lubiprostone-d7 Phenylmethyl Ester

11-O-Tetrahydropyranyl-15-O-tert-butyldimethylsilyl-lubiprostone-d7 Phenylmethyl Ester

  • Catalogue No.:PA STI 082200

  • CAS :

    1346597-45-2

  • Molecular Formula : C38H55D7F2O6Si

  • Molecular Weight : 688.02

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Drug Reference Standards & Impurity Synthesis in India
PA STI 082230

O-Tetrahydropyranyl Lubiprostone-d7

O-Tetrahydropyranyl Lubiprostone-d7

  • Catalogue No.:PA STI 082230

  • CAS :

    1246812-24-7

  • Molecular Formula : C25H33D7F2O6

  • Molecular Weight : 481.62

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Drug Reference Standards & Impurity Synthesis in India
PA 12 87550

(7α,11)-Dihydroxy-5-keto-12,12-difluorotetranorprosta-1,16-dioic Acid

(7α,11)-Dihydroxy-5-keto-12,12-difluorotetranorprosta-1,16-dioic Acid

  • Catalogue No.:PA 12 87550

  • CAS :

    1246812-13-4

  • Molecular Formula : C16H24F2O7

  • Molecular Weight : 366.36

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Drug Reference Standards & Impurity Synthesis in India
PA 12 87560

15-Hydroxy Lubiprostone

15-Hydroxy Lubiprostone

  • Catalogue No.:PA 12 87560

  • CAS :

    475992-30-4

  • Molecular Formula : C20H34F2O5

  • Molecular Weight : 392.48

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871000

7-((1R,2R,3R)-3-(Benzyloxy)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl)heptanoic Acid

7-((1R,2R,3R)-3-(Benzyloxy)-2-(4,4-difluoro-3-oxooctyl)-5-oxocyclopentyl)heptanoic Acid

  • Catalogue No.:PA 12 0871000

  • CAS :

    NA

  • Molecular Formula : C27H38F2O5

  • Molecular Weight : 480.58

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871001

7-((1R,2S)-2-(4,4-Difluoro-3-oxooctyl)-5-oxocyclopent-3-en-1-yl)heptanoic Acid

7-((1R,2S)-2-(4,4-Difluoro-3-oxooctyl)-5-oxocyclopent-3-en-1-yl)heptanoic Acid

  • Catalogue No.:PA 12 0871001

  • CAS :

    2196182-47-3

  • Molecular Formula : C20H30F2O4

  • Molecular Weight : 372.45

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871002

7-((2R,4aR,5S,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic Acid

7-((2R,4aR,5S,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic Acid

  • Catalogue No.:PA 12 0871002

  • CAS :

    1263283-38-0

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.47

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871003

7-(3-(1,1-difluoropentyl)-3-hydroxy-4-oxo-1,2,3,3a,4,6a-hexahydropentalen-3a-yl)heptanoic acid

7-(3-(1,1-difluoropentyl)-3-hydroxy-4-oxo-1,2,3,3a,4,6a-hexahydropentalen-3a-yl)heptanoic acid

  • Catalogue No.:PA 12 0871003

  • CAS :

    NA

  • Molecular Formula : C20H30F2O4

  • Molecular Weight : 372.45

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871004

7-(2-(1,1-Difluoropentyl)-2,8-dihydroxy-7-oxobicyclo[3.2.1]octan-6-yl)heptanoic acid

7-(2-(1,1-Difluoropentyl)-2,8-dihydroxy-7-oxobicyclo[3.2.1]octan-6-yl)heptanoic acid

  • Catalogue No.:PA 12 0871004

  • CAS :

    NA

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.47

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871005

(3aR,4R,5R,6aS)-2-oxo-5-((Tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-4-carbaldehyde

(3aR,4R,5R,6aS)-2-oxo-5-((Tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-4-carbaldehyde

  • Catalogue No.:PA 12 0871005

  • CAS :

    32233-41-3

  • Molecular Formula : C13H18O5

  • Molecular Weight : 254.28

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871006

(3AR,4S,5R,6aS)-4-(Hydroxymethyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one

(3AR,4S,5R,6aS)-4-(Hydroxymethyl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one

  • Catalogue No.:PA 12 0871006

  • CAS :

    69222-61-3

  • Molecular Formula : C13H20O5

  • Molecular Weight : 256.3

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871009

rel-(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one

rel-(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one

  • Catalogue No.:PA 12 0871009

  • CAS :

    54423-47-1

  • Molecular Formula : C8H12O4

  • Molecular Weight : 172.18

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871007

7-((1R,2R,3S)-2-(4,4-difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid

7-((1R,2R,3S)-2-(4,4-difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid

  • Catalogue No.:PA 12 0871007

  • CAS :

    NA

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.47

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Drug Reference Standards & Impurity Synthesis in India
PA STI 088979

7-((1R,2R,3R)-2-(4,4-difluoro-3-hydroxyoctyl-6,6,7,7,8,8,8-d7)-3-hydroxy-5-oxocyclopentyl)heptanoic acid

7-((1R,2R,3R)-2-(4,4-difluoro-3-hydroxyoctyl-6,6,7,7,8,8,8-d7)-3-hydroxy-5-oxocyclopentyl)heptanoic acid

  • Catalogue No.:PA STI 088979

  • CAS :

    1217511-55-1

  • Molecular Formula : C20H27D7F2O5

  • Molecular Weight : 399.53

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Drug Reference Standards & Impurity Synthesis in India
PA STI 088977

7-((1R,2R,3R)-2-(4,4-Difluoro-3-hydroxyoctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic-3,3,4,4-d4 acid

7-((1R,2R,3R)-2-(4,4-Difluoro-3-hydroxyoctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic-3,3,4,4-d4 acid

  • Catalogue No.:PA STI 088977

  • CAS :

    NA

  • Molecular Formula : C20H30D4F2O5

  • Molecular Weight : 396.51

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871008

7-((1S,2R,3R)-2-(4,4-Difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid

7-((1S,2R,3R)-2-(4,4-Difluoro-3-oxooctyl)-3-hydroxy-5-oxocyclopentyl)heptanoic acid

  • Catalogue No.:PA 12 0871008

  • CAS :

    NA

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.47

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871010

Lubiprostone hemiketal

Lubiprostone hemiketal

  • Catalogue No.:PA 12 0871010

  • CAS :

    333963-40-9

  • Molecular Formula : C20H32F2O5

  • Molecular Weight : 390.47

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871011

O-Tetrahydropyranyl Lubiprostone

O-Tetrahydropyranyl Lubiprostone

  • Catalogue No.:PA 12 0871011

  • CAS :

    876068-08-5

  • Molecular Formula : C25H40F2O6

  • Molecular Weight : 474.59

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871012

Cyclohexylmethyl 7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoate

Cyclohexylmethyl 7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoate

  • Catalogue No.:PA 12 0871012

  • CAS :

    NA

  • Molecular Formula : C27H44F2O5

  • Molecular Weight : 486.64

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871013

Benzyl (Z)-7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)hept-5-enoate

Benzyl (Z)-7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)hept-5-enoate

  • Catalogue No.:PA 12 0871013

  • CAS :

    1447733-80-3

  • Molecular Formula : C27H36F2O5

  • Molecular Weight : 478.58

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871014

7-((1R,2R)-2-(4,4-Difluoro-3-oxooctyl)-5-oxocyclopent-3-en-1-yl)heptanamide

7-((1R,2R)-2-(4,4-Difluoro-3-oxooctyl)-5-oxocyclopent-3-en-1-yl)heptanamide

  • Catalogue No.:PA 12 0871014

  • CAS :

    NA

  • Molecular Formula : C20H31F2NO3

  • Molecular Weight : 371.47

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871015

Benzyl (Z)-7-((1R,2R,3R)-2-((E)-4,4-difluoro-3-hydroxyoct-1-en-1-yl)-5-hydroxy-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)hept-5-enoate

Benzyl (Z)-7-((1R,2R,3R)-2-((E)-4,4-difluoro-3-hydroxyoct-1-en-1-yl)-5-hydroxy-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)hept-5-enoate

  • Catalogue No.:PA 12 0871015

  • CAS :

    NA

  • Molecular Formula : C32H46F2O6

  • Molecular Weight : 564.71

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871016

Benzyl (Z)-7-((1R,2R,3R,5S)-2-(4,4-difluoro-3-oxooctyl)-5-hydroxy-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)hept-5-enoate

Benzyl (Z)-7-((1R,2R,3R,5S)-2-(4,4-difluoro-3-oxooctyl)-5-hydroxy-3-((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)hept-5-enoate

  • Catalogue No.:PA 12 0871016

  • CAS :

    NA

  • Molecular Formula : C32H46F2O6

  • Molecular Weight : 564.71

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Drug Reference Standards & Impurity Synthesis in India
PA 12 0871017

13,14-Dihydro-15-keto Prostaglandin E1

13,14-Dihydro-15-keto Prostaglandin E1

  • Catalogue No.:PA 12 0871017

  • CAS :

    5094-14-4

  • Molecular Formula : C20H34O5

  • Molecular Weight : 354.49

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