lurasidone and its Impurities
An antipsychotic drug which is used for the treatment of biolar diseases. It acts as an antagonist to doamine D2, D3, D4 receptors. Lurasidone is also useful for treating the cognitive and memory deficits seen in schizophrenia. Reference standards of Lurasidone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, hydrochloride (1:1), (3aR,4R,7S,7aS)-rel;
4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, hydrochloride (1:1), (3aR,4R,7S,7aS)-rel;
Catalogue No.:PA 65 0211003
CAS :
139563-24-9
Molecular Formula : C28H37ClN4O2S
Molecular Weight : 529.14
(3aR,4S,7S,7aS)-2-(((1R,2R)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)tetrahydro-1H-4,7-methanoisoindole-1,3,5(2H,4H)-trione
(3aR,4S,7S,7aS)-2-(((1R,2R)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)tetrahydro-1H-4,7-methanoisoindole-1,3,5(2H,4H)-trione
Catalogue No.:PA 65 0211005
CAS :
1309363-49-2
Molecular Formula : C28H34N4O3S
Molecular Weight : 506.67
(1S,4R)-3-((((1R,2R)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid
(1S,4R)-3-((((1R,2R)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)carbamoyl)bicyclo[2.2.1]heptane-2-carboxylic acid
Catalogue No.:PA 65 0211007
CAS :
NA
Molecular Formula : C28H38N4O3S
Molecular Weight : 510.7
(3aR,4R,7S,7aS)-2-(((1R,2S)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
(3aR,4R,7S,7aS)-2-(((1R,2S)-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
Catalogue No.:PA 65 0211009
CAS :
1318074-22-4
Molecular Formula : C28H36N4O2S
Molecular Weight : 492.68
(3aR,4S,7R,7aS)-2-(((1R,2R)-2-(Hydroxymethyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
(3aR,4S,7R,7aS)-2-(((1R,2R)-2-(Hydroxymethyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
Catalogue No.:PA 65 0211011
CAS :
1421374-93-7
Molecular Formula : C17H25NO3
Molecular Weight : 291.39
