Medrysone and its Impurities

Medrysone, also known as hydroxymethylprogesterone, methylhydroxyprogesterone, or hydroxymesterone, as well as 6α-methyl-11β-hydroxyprogesterone or 6α-methyl-11β-hydroxypregn-4-ene-3,20-dione, is a synthetic glucocorticoid that is or has been used in the treatment of inflammatory eye diseases. Reference standards of Medrysone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.