Midazolam-impurities | Pharmaffiliates

midazolam and its Impurities

A benzodiazepine class of medication, Midazolamworks through the GABA neurotransmitter. It is used for the purpoes of anesthesia, procedural sedation, sleeping trouble, and severe agitation. Overdose causes toxicity. Reference standards of Midazolam API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 58 results for midazolam Impurities
PA 13 0450051

Midazolam - Impurity E (Dimaleate Salt)

[(2RS)-7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine Dimaleate


  • Catalogue No.:PA 13 0450051

  • CAS :

    59469-29-3

  • Molecular Formula : C24H23ClFN3O8

  • Molecular Weight : 535.91

15% Off
PA 13 0450071

Midazolam - Impurity G (Maleate Salt)

Desfluoromidazolam Maleate


  • Catalogue No.:PA 13 0450071

  • CAS :

    NA

  • Molecular Formula : C22H18ClN3O4

  • Molecular Weight : 423.85

15% Off
PA 13 0451006

Midazolam 5-oxide

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-oxide


  • Catalogue No.:PA 13 0451006

  • CAS :

    59468-83-6

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

15% Off
PA 13 45010

Midazolam - Impurity A

(6RS)-8-Chloro-6-(2-fluorophenyl)-1-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine


  • Catalogue No.:PA 13 45010

  • CAS :

    59468-07-4

  • Molecular Formula : C18H15ClFN3

  • Molecular Weight : 327.78

15% Off
PA 13 45030

Midazolam - Impurity C

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid


  • Catalogue No.:PA 13 45030

  • CAS :

    59468-44-9

  • Molecular Formula : C19H13ClFN3O2

  • Molecular Weight : 369.78

15% Off
PA 13 45040

Midazolam - Impurity D

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-oxide


  • Catalogue No.:PA 13 45040

  • CAS :

    59468-83-6

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

15% Off
PA 13 45050

Midazolam - Impurity E

[(2RS)-7-Chloro-5-(2-fluorophenyl)2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine


  • Catalogue No.:PA 13 45050

  • CAS :

    59467-64-0

  • Molecular Formula : C16H15ClFN3

  • Molecular Weight : 303.76

15% Off
PA 13 45060

Midazolam - Impurity F

7-Chloro-5-(2-fluoropheny)-1,3-dihydro-2H-1,4-benzodiazepin-2-one


  • Catalogue No.:PA 13 45060

  • CAS :

    2886-65-9

  • Molecular Formula : C15H10ClFN2O

  • Molecular Weight : 288.70

15% Off
PA 13 45080

Midazolam - Impurity H

6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline


  • Catalogue No.:PA 13 45080

  • CAS :

    119401-13-7

  • Molecular Formula : C15H10ClFN2

  • Molecular Weight : 272.70

15% Off
PA 13 45090

Midazolam - Impurity I

(3aRS)-8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepin


  • Catalogue No.:PA 13 45090

  • CAS :

    59467-69-5

  • Molecular Formula : C18H15ClFN3

  • Molecular Weight : 327.78

15% Off
PA 13 45100

Midazolam - Impurity J

8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4,5,6-tetrahydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine


  • Catalogue No.:PA 13 45100

  • CAS :

    59469-08-8

  • Molecular Formula : C18H17ClFN3

  • Molecular Weight : 329.80

15% Off
PA 13 45520

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-4-oxide

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-4-oxide


  • Catalogue No.:PA 13 45520

  • CAS :

    NA

  • Molecular Formula : C16H13ClFN3O3

  • Molecular Weight : 349.74

15% Off
PA 13 45530

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide


  • Catalogue No.:PA 13 45530

  • CAS :

    60656-76-0

  • Molecular Formula : C16H11ClFN3O3

  • Molecular Weight : 347.73

15% Off
PAI 13 008010

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide


  • Catalogue No.:PAI 13 008010

  • CAS :

    60656-72-6

  • Molecular Formula : C15H11Cl2FN2O

  • Molecular Weight : 325.16

15% Off
PAI 13 008020

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)quinazoline 3-oxide

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)quinazoline 3-oxide


  • Catalogue No.:PAI 13 008020

  • CAS :

    60656-74-8

  • Molecular Formula : C15H9Cl2FN2O

  • Molecular Weight : 323.15

15% Off
PAI 13 008106

Ethyl 8-chloro-6-(2-fluorophenyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

Ethyl 8-chloro-6-(2-fluorophenyl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate


  • Catalogue No.:PAI 13 008106

  • CAS :

    69585-93-9

  • Molecular Formula : C20H15ClFN3O2

  • Molecular Weight : 383.81

15% Off
PA 13 45070

Midazolam - Impurity G

Desfluoromidazolam


  • Catalogue No.:PA 13 45070

  • CAS :

    59467-86-6

  • Molecular Formula : C18H14ClN3

  • Molecular Weight : 307.78

PA 13 45510

7-Chloro-1-(3-fluorophenyl)-3-methylidene-2-nitro-4-oxido-2H-1,4-benzodiazepin-4-ium

7-Chloro-1-(3-fluorophenyl)-3-methylidene-2-nitro-4-oxido-2H-1,4-benzodiazepin-4-ium


  • Catalogue No.:PA 13 45510

  • CAS :

    NA

  • Molecular Formula : C16H11ClFN3O3

  • Molecular Weight : 347.72

PA STI 019910

N-((7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide-13C2

N-((7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide-13C2


  • Catalogue No.:PA STI 019910

  • CAS :

    2724512-83-6

  • Molecular Formula : C1613C2H17ClFN3O

  • Molecular Weight : 347.78

PAI 13 008030

7-Chloro-5-(2-fluorophenyl)-2-(nitromethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

7-Chloro-5-(2-fluorophenyl)-2-(nitromethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide


  • Catalogue No.:PAI 13 008030

  • CAS :

    NA

  • Molecular Formula : C16H13ClFN3O3

  • Molecular Weight : 349.75

PAI 13 008040

N-((1-Acetyl-7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide

N-((1-Acetyl-7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide


  • Catalogue No.:PAI 13 008040

  • CAS :

    NA

  • Molecular Formula : C20H19ClFN3O2

  • Molecular Weight : 387.84

PAI 13 008050

6-Chloro-2-(chloromethyl)-4-phenyl-1,2-dihydroquinazoline 3-oxide

6-Chloro-2-(chloromethyl)-4-phenyl-1,2-dihydroquinazoline 3-oxide


  • Catalogue No.:PAI 13 008050

  • CAS :

    NA

  • Molecular Formula : C15H12Cl2N2O

  • Molecular Weight : 307.17

PAI 13 008060

7-Chloro-2-(nitromethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

7-Chloro-2-(nitromethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide


  • Catalogue No.:PAI 13 008060

  • CAS :

    NA

  • Molecular Formula : C16H14ClN3O3

  • Molecular Weight : 331.76

PAI 13 008070

(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine

(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine


  • Catalogue No.:PAI 13 008070

  • CAS :

    NA

  • Molecular Formula : C16H16ClN3

  • Molecular Weight : 285.78

PAI 13 008080

8-Chloro-1-methyl-6-phenyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine

8-Chloro-1-methyl-6-phenyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine


  • Catalogue No.:PAI 13 008080

  • CAS :

    NA

  • Molecular Formula : C18H16ClN3

  • Molecular Weight : 309.80

PAI 13 008090

6-Chloro-4-(2-fluorophenyl)-2-methyl-1,2-dihydroquinazoline 3-oxide

6-Chloro-4-(2-fluorophenyl)-2-methyl-1,2-dihydroquinazoline 3-oxide


  • Catalogue No.:PAI 13 008090

  • CAS :

    NA

  • Molecular Formula : C15H12ClFN2O

  • Molecular Weight : 290.72

PAI 13 008100

6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline 3-oxide

6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline 3-oxide


  • Catalogue No.:PAI 13 008100

  • CAS :

    NA

  • Molecular Formula : C15H10ClFN2O

  • Molecular Weight : 288.71

PA 13 45540

1′-Hydroxymidazolam

1′-Hydroxymidazolam


  • Catalogue No.:PA 13 45540

  • CAS :

    59468-90-5

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

PA EPY0000562

Midazolam impurity C (Y0000562)

Midazolam impurity C (Y0000562)


  • Catalogue No.:PA EPY0000562

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 13 45550

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone


  • Catalogue No.:PA 13 45550

  • CAS :

    84425-62-7

  • Molecular Formula : C18H15ClFN3O

  • Molecular Weight : 343.79

PA 13 0451000

8-Chloro-6-(2-fluorophenyl)-3a-hydroxy-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-one

8-Chloro-6-(2-fluorophenyl)-3a-hydroxy-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-one


  • Catalogue No.:PA 13 0451000

  • CAS :

    NA

  • Molecular Formula : C18H13ClFN3O2

  • Molecular Weight : 357.77

PA 13 0451001

8-Chloro-6-(2-fluorophenyl)-1-methyl-3H-benzo[f]imidazo[1,5-a][1,4]diazepine

8-Chloro-6-(2-fluorophenyl)-1-methyl-3H-benzo[f]imidazo[1,5-a][1,4]diazepine


  • Catalogue No.:PA 13 0451001

  • CAS :

    NA

  • Molecular Formula : C18H13ClFN3

  • Molecular Weight : 325.77

PA 13 0451002

4-Hydroxymidazolam

4-Hydroxymidazolam


  • Catalogue No.:PA 13 0451002

  • CAS :

    59468-85-8

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

PA 13 0451003

3,5-Dichloropropiophenone

3,5-Dichloropropiophenone


  • Catalogue No.:PA 13 0451003

  • CAS :

    92821-92-6

  • Molecular Formula : C9H8Cl2O

  • Molecular Weight : 203.06

PA 13 0451004

3',4'-Dichloropropiophenone

3',4'-Dichloropropiophenone


  • Catalogue No.:PA 13 0451004

  • CAS :

    6582-42-9

  • Molecular Formula : C9H8Cl2O

  • Molecular Weight : 203.06

PA 13 0451005

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone Dihydrochloride

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone Dihydrochloride


  • Catalogue No.:PA 13 0451005

  • CAS :

    59468-73-4

  • Molecular Formula : C18H17Cl3FN3O

  • Molecular Weight : 416.7

PA 13 0451008

1'-Hydroxy Midazolam-β-D-glucuronide

1'-Hydroxy Midazolam-β-D-glucuronide


  • Catalogue No.:PA 13 0451008

  • CAS :

    81256-81-7

  • Molecular Formula : C24H21ClFN3O7

  • Molecular Weight : 517.89

PA 13 0451009

4-Hydroxymidazolam b-D-glucuronide

4-Hydroxymidazolam b-D-glucuronide


  • Catalogue No.:PA 13 0451009

  • CAS :

    81256-82-8

  • Molecular Formula : C24H21ClFN3O7

  • Molecular Weight : 517.89

PA STI 088779

4-Hydroxy Midazolam-d5 Methanoate

4-Hydroxy Midazolam-d5 Methanoate


  • Catalogue No.:PA STI 088779

  • CAS :

    1276584-44-1

  • Molecular Formula : C19H12D5ClFN3O2

  • Molecular Weight : 378.84

PA 13 0451010

N-((7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide

N-((7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide


  • Catalogue No.:PA 13 0451010

  • CAS :

    59467-68-4

  • Molecular Formula : C18H17ClFN3O

  • Molecular Weight : 345.8

PA 13 0451011

1’-Acetoxy Midazolam N2-β-D-glucuronide

1’-Acetoxy Midazolam N2-β-D-glucuronide


  • Catalogue No.:PA 13 0451011

  • CAS :

    1014695-26-1

  • Molecular Formula : C24H21ClFN3O7

  • Molecular Weight : 517.89

PA STI 088890

Midazolam 2,5-Dioxide-d6

Midazolam 2,5-Dioxide-d6


  • Catalogue No.:PA STI 088890

  • CAS :

    1215321-98-4

  • Molecular Formula : C18H7D6ClFN3O2

  • Molecular Weight : 363.81

PA STI 088868

1’-Hydroxy Midazolam-13C3

1’-Hydroxy Midazolam-13C3


  • Catalogue No.:PA STI 088868

  • CAS :

    1189677-14-2

  • Molecular Formula : C1513C3H13ClFN3O

  • Molecular Weight : 344.75

PA 13 0451012

(E)-7-Chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

(E)-7-Chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide


  • Catalogue No.:PA 13 0451012

  • CAS :

    1099229-51-2

  • Molecular Formula : C16H11ClFN3O3

  • Molecular Weight : 347.73

PAI 13 008101

(4-Chloro-2-(2-Fluorobenzoyl)phenyl)glycinoyl Bromide

(4-Chloro-2-(2-Fluorobenzoyl)phenyl)glycinoyl Bromide


  • Catalogue No.:PAI 13 008101

  • CAS :

    NA

  • Molecular Formula : C15H10BrClFNO2

  • Molecular Weight : 370.6

PAI 13 008102

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl diethyl Phosphate

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl diethyl Phosphate


  • Catalogue No.:PAI 13 008102

  • CAS :

    NA

  • Molecular Formula : C19H21ClFN2O4P

  • Molecular Weight : 426.81

PAI 13 008103

Ethyl 8-chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

Ethyl 8-chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate


  • Catalogue No.:PAI 13 008103

  • CAS :

    NA

  • Molecular Formula : C21H19ClFN3O2

  • Molecular Weight : 399.85

PAI 13 008104

Ethyl 8-chloro-6-(2-fluorophenyl)-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

Ethyl 8-chloro-6-(2-fluorophenyl)-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate


  • Catalogue No.:PAI 13 008104

  • CAS :

    NA

  • Molecular Formula : C20H17ClFN3O2

  • Molecular Weight : 385.82

PAI 13 008105

Ethyl 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

Ethyl 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate


  • Catalogue No.:PAI 13 008105

  • CAS :

    59469-49-7

  • Molecular Formula : C21H17ClFN3O2

  • Molecular Weight : 397.83

PA 13 0451013

Ethyl 2-acetamido-2-(7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-ylidene)acetate

Ethyl 2-acetamido-2-(7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-ylidene)acetate


  • Catalogue No.:PA 13 0451013

  • CAS :

    59469-47-5

  • Molecular Formula : C21H19ClFN3O3

  • Molecular Weight : 415.85

PA 13 0451014

Ethyl 8-chloro-6-(2-fluorophenyl)-1-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

Ethyl 8-chloro-6-(2-fluorophenyl)-1-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate


  • Catalogue No.:PA 13 0451014

  • CAS :

    59470-13-2

  • Molecular Formula : C26H19ClFN3O2

  • Molecular Weight : 459.91

PAI 13 008107

(Z)-7-Chloro-2-(nitromethylene)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

(Z)-7-Chloro-2-(nitromethylene)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide


  • Catalogue No.:PAI 13 008107

  • CAS :

    NA

  • Molecular Formula : C16H12ClN3O3

  • Molecular Weight : 329.74

PAI 13 008108

(Z)-(7-Chloro-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-ylidene)methanamine

(Z)-(7-Chloro-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-ylidene)methanamine


  • Catalogue No.:PAI 13 008108

  • CAS :

    NA

  • Molecular Formula : C16H14ClN3

  • Molecular Weight : 283.76

PAI 13 008109

4-Chloro-1-methyl-6-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine Maleate

4-Chloro-1-methyl-6-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine Maleate


  • Catalogue No.:PAI 13 008109

  • CAS :

    NA

  • Molecular Formula : C22H18ClN3O4

  • Molecular Weight : 423.85

PA 13 0451015

Midazolam Maleic Acid Adduct

Midazolam Maleic Acid Adduct


  • Catalogue No.:PA 13 0451015

  • CAS :

    2531288-23-8

  • Molecular Formula : C22H17ClFN3O4

  • Molecular Weight : 441.84

PAI 13 008110

Dimethyl 2-(7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-ylidene)malonate

Dimethyl 2-(7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-ylidene)malonate


  • Catalogue No.:PAI 13 008110

  • CAS :

    59468-39-2

  • Molecular Formula : C20H16ClFN2O4

  • Molecular Weight : 402.81

PAI 13 008111

Methyl (E)-2-(7-chloro-5-(2-fluorophenyl)-3H-benzo[e][1,4]diazepin-2-yl)-2-(hydroxyimino)acetate

Methyl (E)-2-(7-chloro-5-(2-fluorophenyl)-3H-benzo[e][1,4]diazepin-2-yl)-2-(hydroxyimino)acetate


  • Catalogue No.:PAI 13 008111

  • CAS :

    NA

  • Molecular Formula : C18H13ClFN3O3

  • Molecular Weight : 373.77

PAI 13 008112

2-Chloro-N-(4-chloro-2-(2-fluorobenzoyl)phenyl)acetamide

2-Chloro-N-(4-chloro-2-(2-fluorobenzoyl)phenyl)acetamide


  • Catalogue No.:PAI 13 008112

  • CAS :

    2836-40-0

  • Molecular Formula : C15H10Cl2FNO2

  • Molecular Weight : 326.15