Midazolam-impurities | Pharmaffiliates

midazolam and its Impurities

A benzodiazepine class of medication, Midazolamworks through the GABA neurotransmitter. It is used for the purpoes of anesthesia, procedural sedation, sleeping trouble, and severe agitation. Overdose causes toxicity. Reference standards of Midazolam API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 43 results for midazolam Impurities
PA 13 45010

Midazolam - Impurity A

(6RS)-8-Chloro-6-(2-fluorophenyl)-1-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine


  • Catalogue No.:PA 13 45010

  • CAS :

    59468-07-4

  • Molecular Formula : C18H15ClFN3

  • Molecular Weight : 327.78

PA 13 45020

Midazolam - Impurity B

8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo[1,5-a][1,4]benzodiazepine


  • Catalogue No.:PA 13 45020

  • CAS :

    59469-74-8

  • Molecular Formula : C18H13ClFN3

  • Molecular Weight : 325.77

PA 13 45040

Midazolam - Impurity D

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-oxide


  • Catalogue No.:PA 13 45040

  • CAS :

    NA

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

PA 13 45050

Midazolam - Impurity E

[(2RS)-7-Chloro-5-(2-fluorophenyl)2,3-dihydro-1H-1,4-benzodiazepin-2-yl]methanamine


  • Catalogue No.:PA 13 45050

  • CAS :

    59467-64-0

  • Molecular Formula : C16H15ClFN3

  • Molecular Weight : 303.76

PA 13 45060

Midazolam - Impurity F

7-Chloro-5-(2-fluoropheny)-1,3-dihydro-2H-1,4-benzodiazepin-2-one


  • Catalogue No.:PA 13 45060

  • CAS :

    NA

  • Molecular Formula : C15H10ClFN2O

  • Molecular Weight : 288.70

PA 13 45070

Midazolam - Impurity G

Desfluoromidazolam


  • Catalogue No.:PA 13 45070

  • CAS :

    59467-86-6

  • Molecular Formula : C18H14ClN3

  • Molecular Weight : 307.78

PA 13 45080

Midazolam - Impurity H

6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline


  • Catalogue No.:PA 13 45080

  • CAS :

    119401-13-7

  • Molecular Formula : C15H10ClFN2

  • Molecular Weight : 272.70

PA 13 45090

Midazolam - Impurity I

(3aRS)-8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4-dihydro-3H-imidazo[1,5-a][1,4]benzodiazepin


  • Catalogue No.:PA 13 45090

  • CAS :

    59467-69-5

  • Molecular Formula : C18H15ClFN3

  • Molecular Weight : 327.78

PA 13 45100

Midazolam - Impurity J

8-Chloro-6-(2-fluorophenyl)-1-methyl-3a,4,5,6-tetrahydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine


  • Catalogue No.:PA 13 45100

  • CAS :

    59469-08-8

  • Molecular Formula : C18H17ClFN3

  • Molecular Weight : 329.80

PA 13 45510

7-Chloro-1-(3-fluorophenyl)-3-methylidene-2-nitro-4-oxido-2H-1,4-benzodiazepin-4-ium

7-Chloro-1-(3-fluorophenyl)-3-methylidene-2-nitro-4-oxido-2H-1,4-benzodiazepin-4-ium


  • Catalogue No.:PA 13 45510

  • CAS :

    NA

  • Molecular Formula : C16H11ClFN3O3

  • Molecular Weight : 347.72

PA 13 45520

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-4-oxide

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H-1,4-benzodiazepine-4-oxide


  • Catalogue No.:PA 13 45520

  • CAS :

    NA

  • Molecular Formula : C16H13ClFN3O3

  • Molecular Weight : 349.74

PA STI 019910

N-((7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide-13C2

N-((7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide-13C2


  • Catalogue No.:PA STI 019910

  • CAS :

    NA

  • Molecular Formula : C1613C2H17ClFN3O

  • Molecular Weight : 347.78

PAI 13 008010

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide


  • Catalogue No.:PAI 13 008010

  • CAS :

    60656-72-6

  • Molecular Formula : C15H11Cl2FN2O

  • Molecular Weight : 325.16

PAI 13 008020

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)quinazoline 3-oxide

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)quinazoline 3-oxide


  • Catalogue No.:PAI 13 008020

  • CAS :

    60656-74-8

  • Molecular Formula : C15H9Cl2FN2O

  • Molecular Weight : 323.15

PAI 13 008030

7-Chloro-5-(2-fluorophenyl)-2-(nitromethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

7-Chloro-5-(2-fluorophenyl)-2-(nitromethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide


  • Catalogue No.:PAI 13 008030

  • CAS :

    NA

  • Molecular Formula : C16H13ClFN3O3

  • Molecular Weight : 349.75

PAI 13 008040

N-((1-Acetyl-7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide

N-((1-Acetyl-7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide


  • Catalogue No.:PAI 13 008040

  • CAS :

    NA

  • Molecular Formula : C20H19ClFN3O2

  • Molecular Weight : 387.84

PAI 13 008050

6-Chloro-2-(chloromethyl)-4-phenyl-1,2-dihydroquinazoline 3-oxide

6-Chloro-2-(chloromethyl)-4-phenyl-1,2-dihydroquinazoline 3-oxide


  • Catalogue No.:PAI 13 008050

  • CAS :

    NA

  • Molecular Formula : C15H12Cl2N2O

  • Molecular Weight : 307.17

PAI 13 008060

7-Chloro-2-(nitromethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide

7-Chloro-2-(nitromethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide


  • Catalogue No.:PAI 13 008060

  • CAS :

    NA

  • Molecular Formula : C16H14ClN3O3

  • Molecular Weight : 331.76

PAI 13 008070

(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine

(7-Chloro-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methanamine


  • Catalogue No.:PAI 13 008070

  • CAS :

    NA

  • Molecular Formula : C16H16ClN3

  • Molecular Weight : 285.78

PAI 13 008080

8-Chloro-1-methyl-6-phenyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine

8-Chloro-1-methyl-6-phenyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepine


  • Catalogue No.:PAI 13 008080

  • CAS :

    NA

  • Molecular Formula : C18H16ClN3

  • Molecular Weight : 309.80

PAI 13 008090

6-Chloro-4-(2-fluorophenyl)-2-methyl-1,2-dihydroquinazoline 3-oxide

6-Chloro-4-(2-fluorophenyl)-2-methyl-1,2-dihydroquinazoline 3-oxide


  • Catalogue No.:PAI 13 008090

  • CAS :

    NA

  • Molecular Formula : C15H12ClFN2O

  • Molecular Weight : 290.72

PAI 13 008100

6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline 3-oxide

6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline 3-oxide


  • Catalogue No.:PAI 13 008100

  • CAS :

    NA

  • Molecular Formula : C15H10ClFN2O

  • Molecular Weight : 288.71

PA 13 45530

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide

7-Chloro-1,3-dihydro-2-nitromethylene-5-(2-fluorophenyl)-2H -1,4-benzodiazepine-4-oxide


  • Catalogue No.:PA 13 45530

  • CAS :

    60656-76-0

  • Molecular Formula : C16H11ClFN3O3

  • Molecular Weight : 347.73

PA 13 45540

1′-Hydroxymidazolam

1′-Hydroxymidazolam


  • Catalogue No.:PA 13 45540

  • CAS :

    59468-90-5

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

PA IPIPRS 104 14

Midazolam (IPRS/104/14)-from IPC


  • Catalogue No.:PA IPIPRS 104 14

  • CAS :

    NA

  • Molecular Formula :

  • Molecular Weight : NA

PA EPM2200000

Midazolam - * psy (M2200000)

Midazolam - * psy (M2200000)


  • Catalogue No.:PA EPM2200000

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0000562

Midazolam impurity C (Y0000562)

Midazolam impurity C (Y0000562)


  • Catalogue No.:PA EPY0000562

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 13 45030

Midazolam - Impurity C

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid


  • Catalogue No.:PA 13 45030

  • CAS :

    59468-44-9

  • Molecular Formula : C19H13ClFN3O2

  • Molecular Weight : 369.78

PA 13 45550

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone


  • Catalogue No.:PA 13 45550

  • CAS :

    84425-62-7

  • Molecular Formula : C18H15ClFN3O

  • Molecular Weight : 343.79

PA 13 0451000

8-Chloro-6-(2-fluorophenyl)-3a-hydroxy-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-one

8-Chloro-6-(2-fluorophenyl)-3a-hydroxy-1-methyl-3a,4-dihydro-3H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-one


  • Catalogue No.:PA 13 0451000

  • CAS :

    NA

  • Molecular Formula : C18H13ClFN3O2

  • Molecular Weight : 357.77

PA 13 0451001

8-Chloro-6-(2-fluorophenyl)-1-methyl-3H-benzo[f]imidazo[1,5-a][1,4]diazepine

8-Chloro-6-(2-fluorophenyl)-1-methyl-3H-benzo[f]imidazo[1,5-a][1,4]diazepine


  • Catalogue No.:PA 13 0451001

  • CAS :

    NA

  • Molecular Formula : C18H13ClFN3

  • Molecular Weight : 325.77

PA 13 0451006

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide


  • Catalogue No.:PA 13 0451006

  • CAS :

    59468-83-6

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

PA 13 0451002

4-Hydroxymidazolam

4-Hydroxymidazolam


  • Catalogue No.:PA 13 0451002

  • CAS :

    59468-85-8

  • Molecular Formula : C18H13ClFN3O

  • Molecular Weight : 341.77

PA 13 0451003

3,5-Dichloropropiophenone

3,5-Dichloropropiophenone


  • Catalogue No.:PA 13 0451003

  • CAS :

    92821-92-6

  • Molecular Formula : C9H8Cl2O

  • Molecular Weight : 203.06

PA 13 0451004

3',4'-Dichloropropiophenone

3',4'-Dichloropropiophenone


  • Catalogue No.:PA 13 0451004

  • CAS :

    6582-42-9

  • Molecular Formula : C9H8Cl2O

  • Molecular Weight : 203.06

PA 13 0451005

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone Dihydrochloride

(2-(5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl)-5-chlorophenyl)(2-fluorophenyl)methanone Dihydrochloride


  • Catalogue No.:PA 13 0451005

  • CAS :

    59468-73-4

  • Molecular Formula : C18H17Cl3FN3O

  • Molecular Weight : 416.7

PA 13 0451008

1'-Hydroxy Midazolam-β-D-glucuronide

1'-Hydroxy Midazolam-β-D-glucuronide


  • Catalogue No.:PA 13 0451008

  • CAS :

    81256-81-7

  • Molecular Formula : C24H21ClFN3O7

  • Molecular Weight : 517.89

PA 13 0451009

4-Hydroxymidazolam b-D-glucuronide

4-Hydroxymidazolam b-D-glucuronide


  • Catalogue No.:PA 13 0451009

  • CAS :

    81256-82-8

  • Molecular Formula : C24H21ClFN3O7

  • Molecular Weight : 517.89

PA STI 088779

4-Hydroxy Midazolam-d5 Methanoate

4-Hydroxy Midazolam-d5 Methanoate


  • Catalogue No.:PA STI 088779

  • CAS :

    1276584-44-1

  • Molecular Formula : C19H12D5ClFN3O2

  • Molecular Weight : 378.84

PA 13 0451010

N-((7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide

N-((7-chloro-5-(2-fluorophenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)methyl)acetamide


  • Catalogue No.:PA 13 0451010

  • CAS :

    59467-68-4

  • Molecular Formula : C18H17ClFN3O

  • Molecular Weight : 345.8

PA 13 0451011

1’-Acetoxy Midazolam N2-β-D-glucuronide

1’-Acetoxy Midazolam N2-β-D-glucuronide


  • Catalogue No.:PA 13 0451011

  • CAS :

    1014695-26-1

  • Molecular Formula : C24H21ClFN3O7

  • Molecular Weight : 517.89

PA STI 088890

Midazolam 2,5-Dioxide-d6

Midazolam 2,5-Dioxide-d6


  • Catalogue No.:PA STI 088890

  • CAS :

    1215321-98-4

  • Molecular Formula : C18H7D6ClFN3O2

  • Molecular Weight : 363.81

PA STI 088868

1’-Hydroxy Midazolam-13C3

1’-Hydroxy Midazolam-13C3


  • Catalogue No.:PA STI 088868

  • CAS :

    1189677-14-2

  • Molecular Formula : C1513C3H13ClFN3O

  • Molecular Weight : 344.75