Mirdametinib and its Impurities

Mirdametinib, also known by its brand name Gomekli, is an oral, highly selective, and potent small molecule inhibitor of mitogen-activated protein kinase kinases 1 and 2 (MEK1/2). Reference standards of Mirdametinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.