mizolastine and its Impurities
Mizolastine is used to reduce the symptoms of hay fever other allergic reactions causing irritation of the eyes and nose. It is under investigation in clinical trial. Reference standards of Mizolastine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
2,6-bis((1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)-4b,7,8a,8b-tetrahydrocyclobuta[1,2-d:3,4-d']dipyrimidine-4,8(3H,4aH)-dione
2,6-bis((1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)-4b,7,8a,8b-tetrahydrocyclobuta[1,2-d:3,4-d']dipyrimidine-4,8(3H,4aH)-dione
Catalogue No.:PA 40 0381004
CAS :
NA
Molecular Formula : C48H50F2N12O2
Molecular Weight : 865.01
5,5'-Methylenebis(2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one)
5,5'-Methylenebis(2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one)
Catalogue No.:PA 40 0381006
CAS :
935860-13-2
Molecular Formula : C49H50F2N12O2
Molecular Weight : 877.02
5,5'-(Ethane-1,1-diyl)bis(2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one)
5,5'-(Ethane-1,1-diyl)bis(2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one)
Catalogue No.:PA 40 0381007
CAS :
NA
Molecular Formula : C50H52F2N12O2
Molecular Weight : 891.04
N-(1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)-4-methoxy-N-methylpyrimidin-2-amine
N-(1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)-4-methoxy-N-methylpyrimidin-2-amine
Catalogue No.:PA 40 0381008
CAS :
935860-12-1
Molecular Formula : C25H27FN6O
Molecular Weight : 446.53
2-((1-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one
2-((1-(1-(2-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one
Catalogue No.:PA 40 0381009
CAS :
NA
Molecular Formula : C24H25FN6O
Molecular Weight : 432.5
2-((1-(1-(3-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one
2-((1-(1-(3-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one
Catalogue No.:PA 40 0381010
CAS :
935860-15-4
Molecular Formula : C24H25FN6O
Molecular Weight : 432.5
2-((1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)-5-((2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)methyl)-6-hydroxypyrimidin-4(3H)-one
2-((1-(1-(4-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)-5-((2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)methyl)-6-hydroxypyrimidin-4(3H)-one
Catalogue No.:PA 40 0381011
CAS :
935860-14-3
Molecular Formula : C49H50F2N12O3
Molecular Weight : 893.02
