Mobocertinib and its Impurities
Mobocertinib is an oral kinase inhibitor targeted against EGFR and used in the treatment of NSCLC with EGFR exon 20 insertion mutations. Reference standards of Mobocertinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(nitroso)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(nitroso)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 13 2901000
CAS :
NA
Molecular Formula : C31H36N8O5
Molecular Weight : 600.68
Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(nitroso)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(nitroso)amino)-2-methoxyphenyl)(nitroso)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 13 2901001
CAS :
NA
Molecular Formula : C31H35N9O6
Molecular Weight : 629.68
Isopropyl 2-((5-acrylamido-2-methoxy-4-(methyl(2-(methyl(nitroso)amino)ethyl)amino)phenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Isopropyl 2-((5-acrylamido-2-methoxy-4-(methyl(2-(methyl(nitroso)amino)ethyl)amino)phenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 13 2901002
CAS :
NA
Molecular Formula : C31H36N8O5
Molecular Weight : 600.68
Isopropyl 2-((5-acrylamido-2-methoxy-4-(methyl(2-(methyl(nitroso)amino)ethyl)amino)phenyl)(nitroso)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Isopropyl 2-((5-acrylamido-2-methoxy-4-(methyl(2-(methyl(nitroso)amino)ethyl)amino)phenyl)(nitroso)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 13 2901003
CAS :
NA
Molecular Formula : C31H35N9O6
Molecular Weight : 629.68
Isopropyl 2-((5-acrylamido-2-methoxy-4-((2-(methyl(nitroso)amino)ethyl)(nitroso)amino)phenyl)(nitroso)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Isopropyl 2-((5-acrylamido-2-methoxy-4-((2-(methyl(nitroso)amino)ethyl)(nitroso)amino)phenyl)(nitroso)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
Catalogue No.:PA 13 2901004
CAS :
NA
Molecular Formula : C30H32N10O7
Molecular Weight : 644.65
