nadolol and its Impurities
Nadolol is used to treat hypertension and for long-term treatment of angina pectoris. It is available as a generic medication. It has also been used to prevent migraine headaches and complications of cirrhosis. Reference standards of Nadolol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
2-((((2R,3S)-8-((S)-2-(tert-Butylamino)propoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)oxy)carbonyl)-2-hydroxymalonic Acid Hydrochloride
2-((((2R,3S)-8-((S)-2-(tert-Butylamino)propoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)oxy)carbonyl)-2-hydroxymalonic Acid Hydrochloride
Catalogue No.:PA 14 02530
CAS :
NA
Molecular Formula : C21H30ClNO9
Molecular Weight : 475.92
2-(tert-Butyl((S)-1-(((6S,7R)-7-(2,2-dicarboxy-2-hydroxyacetoxy)-6-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy)propan-2-yl)carbamoyl)-2-hydroxymalonic Acid
2-(tert-Butyl((S)-1-(((6S,7R)-7-(2,2-dicarboxy-2-hydroxyacetoxy)-6-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy)propan-2-yl)carbamoyl)-2-hydroxymalonic Acid
Catalogue No.:PA 14 02540
CAS :
NA
Molecular Formula : C25H31NO15
Molecular Weight : 585.52
(5aR,11aS)-7-((S)-2-(tert-Butylamino)propoxy)-3-hydroxy-2,4-dioxo-3,4,5a,6,11,11a-hexahydro-2H-naphtho[2,3-b][1,4]dioxepine-3-carboxylic acid hydrochloride
(5aR,11aS)-7-((S)-2-(tert-Butylamino)propoxy)-3-hydroxy-2,4-dioxo-3,4,5a,6,11,11a-hexahydro-2H-naphtho[2,3-b][1,4]dioxepine-3-carboxylic acid hydrochloride
Catalogue No.:PA 14 02550
CAS :
NA
Molecular Formula : C21H28ClNO8
Molecular Weight : 457.9
2-(tert-Butyl((2S)-1-(((5aR,11aS)-3-carboxy-3-hydroxy-2,4-dioxo-3,4,5a,6,11,11a-hexahydro-2H-naphtho[2,3-b][1,4]dioxepin-7-yl)oxy)propan-2-yl)carbamoyl)-2-hydroxymalonic Acid
2-(tert-Butyl((2S)-1-(((5aR,11aS)-3-carboxy-3-hydroxy-2,4-dioxo-3,4,5a,6,11,11a-hexahydro-2H-naphtho[2,3-b][1,4]dioxepin-7-yl)oxy)propan-2-yl)carbamoyl)-2-hydroxymalonic Acid
Catalogue No.:PA 14 02560
CAS :
NA
Molecular Formula : C25H29NO14
Molecular Weight : 567.5
(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 2-hydroxypropane-1,2,3-tricarboxylate
(2R,3S)-5-(3-(tert-Butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol 2-hydroxypropane-1,2,3-tricarboxylate
Catalogue No.:PA 14 0021000
CAS :
NA
Molecular Formula : C23H35NO11
Molecular Weight : 501.53
(2SR,3RS)-5-(3-{[(6RS,7SR)-6,7-Dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]oxy}-2-hydroxypropoxy)- 1,2,3,4-tetrahydronaphthalene-2,3-diol) and (1,3-Bis[(6R,7S)-6,7-dihydroxy-5,6,7,8-tetrahydronaphthalene-1-yloxy]propane-2-ol
(2SR,3RS)-5-(3-{[(6RS,7SR)-6,7-Dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]oxy}-2-hydroxypropoxy)- 1,2,3,4-tetrahydronaphthalene-2,3-diol) and (1,3-Bis[(6R,7S)-6,7-dihydroxy-5,6,7,8-tetrahydronaphthalene-1-yloxy]propane-2-ol
Catalogue No.:PA 14 0021001
CAS :
NA
Molecular Formula : C23H28O7
Molecular Weight : 416.46
5,5'-(((Tert-butylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy))bis(1,2,3,4-tetrahydronaphthalene-2,3-diol)
5,5'-(((Tert-butylazanediyl)bis(2-hydroxypropane-3,1-diyl))bis(oxy))bis(1,2,3,4-tetrahydronaphthalene-2,3-diol)
Catalogue No.:PA 14 0021003
CAS :
67247-26-1
Molecular Formula : C30H43NO8
Molecular Weight : 545.67
2-(2-((8-(3-(tert-Butylamino)-2-hydroxypropoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)oxy)-2-oxoethyl)-2-hydroxysuccinic Acid
2-(2-((8-(3-(tert-Butylamino)-2-hydroxypropoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)oxy)-2-oxoethyl)-2-hydroxysuccinic Acid
Catalogue No.:PA 14 0021006
CAS :
NA
Molecular Formula : C23H33NO10
Molecular Weight : 483.51
1-(tert-Butylamino)-3-((2,2-dimethyl-3a,4,9,9a-tetrahydronaphtho[2,3-d][1,3]dioxol-5-yl)oxy)propan-2-ol
1-(tert-Butylamino)-3-((2,2-dimethyl-3a,4,9,9a-tetrahydronaphtho[2,3-d][1,3]dioxol-5-yl)oxy)propan-2-ol
Catalogue No.:PA 14 0021012
CAS :
52187-21-0
Molecular Formula : C20H31NO4
Molecular Weight : 349.47
