neratinib and its Impurities

Neratinib is used as an adjuvant therapy in people with early stage breast cancer in which HER2 is overexpressed, after the person receives treatment with trastuzumab. It is a tyrosine kinase inhibitor anticancer drug. Reference standards of Neratinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 21 results for neratinib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 14 74000

Neratinib

Neratinib

  • Catalogue No.:PA 14 74000

  • CAS :

    698387-09-6

  • Molecular Formula : C30H29ClN6O3

  • Molecular Weight : 557.04

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Drug Reference Standards & Impurity Synthesis in India
PA STI 067320

Neratinib-d6

Neratinib-d6

  • Catalogue No.:PA STI 067320

  • CAS :

    1259519-18-0

  • Molecular Formula : C30H23D6ClN6O3

  • Molecular Weight : 563.08

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Drug Reference Standards & Impurity Synthesis in India
PA 14 74510

4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(2-hydroxy-5-oxopyrrolidin-1-yl)quinoline-3-carbonitrile

4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxy-6-(2-hydroxy-5-oxopyrrolidin-1-yl)quinoline-3-carbonitrile

  • Catalogue No.:PA 14 74510

  • CAS :

    1144516-15-3

  • Molecular Formula : C28H24ClN5O4

  • Molecular Weight : 529.98

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Drug Reference Standards & Impurity Synthesis in India
PA 14 74520

(E)-4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinoline-3-carboxylic Acid

(E)-4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinoline-3-carboxylic Acid

  • Catalogue No.:PA 14 74520

  • CAS :

    NA

  • Molecular Formula : C30H30ClN5O5

  • Molecular Weight : 576.05

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Drug Reference Standards & Impurity Synthesis in India
PA 14 74530

N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)acetamide

N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)acetamide

  • Catalogue No.:PA 14 74530

  • CAS :

    2748212-19-1

  • Molecular Formula : C25H20ClN5O3

  • Molecular Weight : 473.92

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Drug Reference Standards & Impurity Synthesis in India
PA 14 74540

(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(methylamino)but-2-enamide

(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(methylamino)but-2-enamide

  • Catalogue No.:PA 14 74540

  • CAS :

    915788-27-1

  • Molecular Formula : C29H27ClN6O3

  • Molecular Weight : 543.02

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Drug Reference Standards & Impurity Synthesis in India
PA 14 74550

(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

  • Catalogue No.:PA 14 74550

  • CAS :

    NA

  • Molecular Formula : C29H27ClN6O3

  • Molecular Weight : 543.02

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Drug Reference Standards & Impurity Synthesis in India
PA 14 74560

(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-hydroxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-hydroxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

  • Catalogue No.:PA 14 74560

  • CAS :

    NA

  • Molecular Formula : C28H25ClN6O3

  • Molecular Weight : 529

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Drug Reference Standards & Impurity Synthesis in India
PA 14 74570

(E)-N-(4-((3-Chloro-4-hydroxyphenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

(E)-N-(4-((3-Chloro-4-hydroxyphenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

  • Catalogue No.:PA 14 74570

  • CAS :

    1895881-83-0

  • Molecular Formula : C24H24ClN5O3

  • Molecular Weight : 465.94

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741000

(Z)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

(Z)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide

  • Catalogue No.:PA 14 0741000

  • CAS :

    2186660-79-5

  • Molecular Formula : C30H29ClN6O3

  • Molecular Weight : 557.05

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741001

N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide

N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide

  • Catalogue No.:PA 14 0741001

  • CAS :

    1144516-20-0

  • Molecular Formula : C25H20ClN5O3

  • Molecular Weight : 473.92

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741002

6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile

6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile

  • Catalogue No.:PA 14 0741002

  • CAS :

    848139-78-6

  • Molecular Formula : C24H20ClN5O2

  • Molecular Weight : 445.91

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741003

Neratinib pyridine N-oxide (M3)

Neratinib pyridine N-oxide (M3)

  • Catalogue No.:PA 14 0741003

  • CAS :

    1376619-94-1

  • Molecular Formula : C30H29ClN6O4

  • Molecular Weight : 573.05

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741004

Neratinib dimethylamine N-oxide (M7)

Neratinib dimethylamine N-oxide (M7)

  • Catalogue No.:PA 14 0741004

  • CAS :

    1376615-55-2

  • Molecular Formula : C30H29ClN6O4

  • Molecular Weight : 573.05

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741005

N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)acetamide

N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)acetamide

  • Catalogue No.:PA 14 0741005

  • CAS :

    915941-95-6

  • Molecular Formula : C26H22ClN5O3

  • Molecular Weight : 487.94

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741006

N-Nitroso Neratinib

N-Nitroso Neratinib

  • Catalogue No.:PA 14 0741006

  • CAS :

    NA

  • Molecular Formula : C30H28ClN7O4

  • Molecular Weight : 586.05

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741007

Neratinib Bis-N-Oxide (M11)

Neratinib Bis-N-Oxide (M11)

  • Catalogue No.:PA 14 0741007

  • CAS :

    NA

  • Molecular Formula : C30H29ClN6O5

  • Molecular Weight : 589.05

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741008

Neratinib Quinoline N-Oxide

Neratinib Quinoline N-Oxide

  • Catalogue No.:PA 14 0741008

  • CAS :

    1348481-03-7

  • Molecular Formula : C30H29ClN6O4

  • Molecular Weight : 573.05

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741009

N-nitroso Desmethyl Neratinib

N-nitroso Desmethyl Neratinib

  • Catalogue No.:PA 14 0741009

  • CAS :

    3050754-68-9

  • Molecular Formula : C29H26ClN7O4

  • Molecular Weight : 572.02

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741010

N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide

N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide

  • Catalogue No.:PA 14 0741010

  • CAS :

    848133-76-6

  • Molecular Formula : C14H12ClN3O2

  • Molecular Weight : 289.72

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0741011

3-Chloro-4-(pyridin-2-ylmethoxy)aniline

3-Chloro-4-(pyridin-2-ylmethoxy)aniline

  • Catalogue No.:PA 14 0741011

  • CAS :

    524955-09-7

  • Molecular Formula : C12H11ClN2O

  • Molecular Weight : 234.68

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