nintedanib and its Impurities

A Nintedanib is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer. It is a small molecule kinase inhibitor. Reference standards of Nintedanib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 19 results for nintedanib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 14 0541072

N-(3-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide

N-(3-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide

  • Catalogue No.:PA 14 0541072

  • CAS :

    652140-28-8

  • Molecular Formula : C14H22N4O

  • Molecular Weight : 262.36

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541073

N-(4-Aminophenyl)-N-methylacetamide

N-(4-Aminophenyl)-N-methylacetamide

  • Catalogue No.:PA 14 0541073

  • CAS :

    119-63-1

  • Molecular Formula : C9H12N2O

  • Molecular Weight : 164.21

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541074

(Z)-3-(((4-(Methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid

(Z)-3-(((4-(Methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid

  • Catalogue No.:PA 14 0541074

  • CAS :

    NA

  • Molecular Formula : C23H19N3O3

  • Molecular Weight : 385.42

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541075

Methyl (Z)-1-acetyl-3-((4-chloro-3-nitrophenyl)(hydroxy)methylene)-2-oxoindoline-6-carboxylate

Methyl (Z)-1-acetyl-3-((4-chloro-3-nitrophenyl)(hydroxy)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541075

  • CAS :

    NA

  • Molecular Formula : C19H13ClN2O7

  • Molecular Weight : 416.77

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541076

(Z)-1-Acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid

(Z)-1-Acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid

  • Catalogue No.:PA 14 0541076

  • CAS :

    1985659-44-6

  • Molecular Formula : C20H17NO5

  • Molecular Weight : 351.36

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541077

Methyl (Z)-1-acetyl-3-(2-methoxybenzylidene)-2-oxoindoline-6-carboxylate

Methyl (Z)-1-acetyl-3-(2-methoxybenzylidene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541077

  • CAS :

    NA

  • Molecular Formula : C20H17NO5

  • Molecular Weight : 351.36

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541078

Ethyl (Z)-1-acetyl-3-(2-ethoxybenzylidene)-2-oxoindoline-6-carboxylate

Ethyl (Z)-1-acetyl-3-(2-ethoxybenzylidene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541078

  • CAS :

    NA

  • Molecular Formula : C22H21NO5

  • Molecular Weight : 379.41

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541079

N-(4-Aminophenyl)-2-(4-(2-((4-aminophenyl)amino)-2-oxoethyl)piperazin-1-yl)-N-methylacetamide

N-(4-Aminophenyl)-2-(4-(2-((4-aminophenyl)amino)-2-oxoethyl)piperazin-1-yl)-N-methylacetamide

  • Catalogue No.:PA 14 0541079

  • CAS :

    NA

  • Molecular Formula : C21H28N6O2

  • Molecular Weight : 396.50

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541067

Methyl (Z)-3-(((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Methyl (Z)-3-(((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541067

  • CAS :

    NA

  • Molecular Formula : C32H35N5O4

  • Molecular Weight : 553.66

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541080

(Z)-2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoacetic Acid

(Z)-2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoacetic Acid

  • Catalogue No.:PA 14 0541080

  • CAS :

    NA

  • Molecular Formula : C26H21N3O6

  • Molecular Weight : 471.47

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541081

N-Methyl-N-(4-nitrophenyl)nitrous amide

N-Methyl-N-(4-nitrophenyl)nitrous amide

  • Catalogue No.:PA 14 0541081

  • CAS :

    NA

  • Molecular Formula : C7H7N3O3

  • Molecular Weight : 181.15

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541082

Methyl (Z)-3-(2-((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)benzylidene)-2-oxoindoline-6-carboxylate

Methyl (Z)-3-(2-((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)benzylidene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541082

  • CAS :

    NA

  • Molecular Formula : C32H35N5O4

  • Molecular Weight : 553.66

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541083

Methyl (E)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Methyl (E)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541083

  • CAS :

    NA

  • Molecular Formula : C30H31N5O4

  • Molecular Weight : 525.61

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541084

Methyl (Z)-3-(((4-(methyl(nitroso)amino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Methyl (Z)-3-(((4-(methyl(nitroso)amino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541084

  • CAS :

    NA

  • Molecular Formula : C24H20N4O4

  • Molecular Weight : 428.45

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541085

N-(4-Aminophenyl)-N-methyl-2-(piperazin-1-yl)acetamide Hydrochloride

N-(4-Aminophenyl)-N-methyl-2-(piperazin-1-yl)acetamide Hydrochloride

  • Catalogue No.:PA 14 0541085

  • CAS :

    NA

  • Molecular Formula : C13H21ClN4O

  • Molecular Weight : 284.79

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541086

Methyl (Z)-1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Methyl (Z)-1-acetyl-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541086

  • CAS :

    NA

  • Molecular Formula : C33H34N6O6

  • Molecular Weight : 610.67

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541087

(Z)-3-(((4-(N-Methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid

(Z)-3-(((4-(N-Methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid

  • Catalogue No.:PA 14 0541087

  • CAS :

    NA

  • Molecular Formula : C30H30N6O5

  • Molecular Weight : 554.61

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541088

Methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541088

  • CAS :

    NA

  • Molecular Formula : C30H30N6O5

  • Molecular Weight : 554.61

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Drug Reference Standards & Impurity Synthesis in India
PA 14 0541089

Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Methyl (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)(nitroso)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541089

  • CAS :

    NA

  • Molecular Formula : C31H32N6O5

  • Molecular Weight : 568.63

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