nintedanib and its Impurities
A Nintedanib is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer. It is a small molecule kinase inhibitor. Reference standards of Nintedanib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


Methyl (Z)-1-acetyl-3-((4-chloro-3-nitrophenyl)(hydroxy)methylene)-2-oxoindoline-6-carboxylate
Methyl (Z)-1-acetyl-3-((4-chloro-3-nitrophenyl)(hydroxy)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 0541075
CAS :
NA
Molecular Formula : C19H13ClN2O7
Molecular Weight : 416.77


Methyl (Z)-3-(((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Methyl (Z)-3-(((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Catalogue No.:PA 14 0541067
CAS :
NA
Molecular Formula : C32H35N5O4
Molecular Weight : 553.66