Nirmatrelvir and its Impurities

Nirmatrelvir is an antiviral medication developed by Pfizer which acts as an orally active 3C-like protease inhibitor. It is part of the nirmatrelvir/ritonavir combination sold under the brand name Paxlovid. Reference standards of Nirmatrelvir API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 27 results for Nirmatrelvir Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 14 1360000

Nirmatrelvir

Nirmatrelvir

  • Catalogue No.:PA 14 1360000

  • CAS :

    2628280-40-8

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361000

(S)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(S)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361000

  • CAS :

    2628280-48-6

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361001

(1R,2S,5S)-N-((S)-1-Amino-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((S)-1-Amino-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361001

  • CAS :

    2755812-81-6

  • Molecular Formula : C23H34F3N5O5

  • Molecular Weight : 517.55

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361002

(1R,2S,5S)-N-((R)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((R)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361002

  • CAS :

    2755812-41-8

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361003

(S)-2-((1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoic Acid

(S)-2-((1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoic Acid

  • Catalogue No.:PA 14 1361003

  • CAS :

    3057189-15-5

  • Molecular Formula : C23H33F3N4O6

  • Molecular Weight : 518.53

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361004

Methyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Methyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

  • Catalogue No.:PA 14 1361004

  • CAS :

    2879641-46-8

  • Molecular Formula : C24H35F3N4O6

  • Molecular Weight : 532.56

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361005

N-((S)-1-((1R,2S,5S)-2-Cyano-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2,2,2-trifluoroacetamide

N-((S)-1-((1R,2S,5S)-2-Cyano-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl)-3,3-dimethyl-1-oxobutan-2-yl)-2,2,2-trifluoroacetamide

  • Catalogue No.:PA 14 1361005

  • CAS :

    2801608-29-5

  • Molecular Formula : C16H22F3N3O2

  • Molecular Weight : 345.37

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361006

 (2S)-3-(2-chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

(2S)-3-(2-chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

  • Catalogue No.:PA 14 1361006

  • CAS :

    NA

  • Molecular Formula : C23H33ClF3N5O4

  • Molecular Weight : 535.99

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361007

Isopropyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

Isopropyl (S)-2-((1R,2S,5S)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamido)-3-((S)-2-oxopyrrolidin-3-yl)propanoate

  • Catalogue No.:PA 14 1361007

  • CAS :

    NA

  • Molecular Formula : C26H39F3N4O6

  • Molecular Weight : 560.62

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361008

(2S,3S)-3-(2-Chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

(2S,3S)-3-(2-Chloropropan-2-yl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-1-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)pyrrolidine-2-carboxamide

  • Catalogue No.:PA 14 1361008

  • CAS :

    NA

  • Molecular Formula : C23H33ClF3N5O4

  • Molecular Weight : 535.99

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089311

Nirmatrelvir-D9

Nirmatrelvir-D9

  • Catalogue No.:PA STI 089311

  • CAS :

    2861202-76-6

  • Molecular Formula : C23H23D9F3N5O4

  • Molecular Weight : 508.59

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361009

(R)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(R)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361009

  • CAS :

    2889532-79-8

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361010

Methyl (1R,2R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

Methyl (1R,2R,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate

  • Catalogue No.:PA 14 1361010

  • CAS :

    1932411-98-7

  • Molecular Formula : C9H15NO2

  • Molecular Weight : 169.22

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361011

(1R,2S,5S)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-N-(2,2,2-trifluoroacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-N-(2,2,2-trifluoroacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361011

  • CAS :

    NA

  • Molecular Formula : C25H31F6N5O5

  • Molecular Weight : 595.54

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361012

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((R)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361012

  • CAS :

    NA

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361013

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1S,2R,5R)-N-((S)-1-Cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361013

  • CAS :

    NA

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361014

(1R,2S,5S)-3-((S)-2-Amino-3,3-dimethylbutanoyl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-3-((S)-2-Amino-3,3-dimethylbutanoyl)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361014

  • CAS :

    2883654-28-0

  • Molecular Formula : C21H33N5O3

  • Molecular Weight : 403.53

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361015

(1R,2S,5S)-3-((S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

(1R,2S,5S)-3-((S)-2-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

  • Catalogue No.:PA 14 1361015

  • CAS :

    394735-37-6

  • Molecular Formula : C19H32N2O5

  • Molecular Weight : 368.47

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361016

(1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

(1R,2S,5S)-3-((S)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

  • Catalogue No.:PA 14 1361016

  • CAS :

    2755812-45-2

  • Molecular Formula : C16H23F3N2O4

  • Molecular Weight : 364.37

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361017

(1R,2S,5S)-3-((R)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

(1R,2S,5S)-3-((R)-3,3-Dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid

  • Catalogue No.:PA 14 1361017

  • CAS :

    NA

  • Molecular Formula : C16H23F3N2O4

  • Molecular Weight : 364.37

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361018

Methyl (S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

Methyl (S)-2-amino-3-((S)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

  • Catalogue No.:PA 14 1361018

  • CAS :

    1429218-41-6

  • Molecular Formula : C8H15ClN2O3

  • Molecular Weight : 222.67

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361019

Methyl (R)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

Methyl (R)-2-amino-3-((R)-2-oxopyrrolidin-3-yl)propanoate Hydrochloride

  • Catalogue No.:PA 14 1361019

  • CAS :

    2738028-87-8

  • Molecular Formula : C8H15ClN2O3

  • Molecular Weight : 222.67

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361020

(S)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(S)-2-Amino-3-((R)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361020

  • CAS :

    NA

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361021

(R)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

(R)-2-Amino-3-((S)-2-oxopyrrolidin-3-yl)propanamide Hydrochloride

  • Catalogue No.:PA 14 1361021

  • CAS :

    NA

  • Molecular Formula : C7H14ClN3O2

  • Molecular Weight : 207.66

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361022

(1R,2S,5S)-N-((R)-1-Cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

(1R,2S,5S)-N-((R)-1-Cyano-2-((R)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide

  • Catalogue No.:PA 14 1361022

  • CAS :

    NA

  • Molecular Formula : C23H32F3N5O4

  • Molecular Weight : 499.54

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Drug Reference Standards & Impurity Synthesis in India
PA 14 1361023

(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile

(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile

  • Catalogue No.:PA 14 1361023

  • CAS :

    1037559-82-2

  • Molecular Formula : C8H12N2

  • Molecular Weight : 136.2

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Drug Reference Standards & Impurity Synthesis in India
PA BSC 13614947

(aS,3S)-a-[(tert-Butyloxycarbonyl)amino]-2-oxo-3-pyrrolidinepropanoic Acid Methyl Ester (BSC)

(aS,3S)-a-[(tert-Butyloxycarbonyl)amino]-2-oxo-3-pyrrolidinepropanoic Acid Methyl Ester

  • Catalogue No.:PA BSC 13614947

  • CAS :

    328086-60-8

  • Molecular Formula : C13H22N2O5

  • Molecular Weight : 286.33

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