Onvansertib and its Impurities

Onvansertib is a third-generation, oral adenosine triphosphate which inhibits tumor growth in patients with acute myeloid leukemia (AML) who are resistant to venetoclax (Venclexta).Reference standards of Onvansertib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.