Palbociclib Hydrochloride and its Impurities

Palbociclib Hydrochloride, sold under the brand name Ibrance among others, is a medication developed by Pfizer for the treatment of HR-positive and HER2-negative breast cancer. Reference standards of Palbociclib Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.