palbociclib and its Impurities
Palbociclib is a drug which is used to treat a certain type of breast cancer. Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy.Reference standards of Palbociclib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
N-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)-2-hydroxyacetamide
N-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)-2-hydroxyacetamide
Catalogue No.:PA 43 0061077
CAS :
NA
Molecular Formula : C22H24N6O4
Molecular Weight : 436.47
2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-(octadecyloxy)-4-oxobutanoic Acid
2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-(octadecyloxy)-4-oxobutanoic Acid
Catalogue No.:PA 43 0061076
CAS :
NA
Molecular Formula : C46H69N7O6
Molecular Weight : 816.1
3-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-(octadecyloxy)-4-oxobutanoic Acid
3-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-(octadecyloxy)-4-oxobutanoic Acid
Catalogue No.:PA 43 0061075
CAS :
NA
Molecular Formula : C46H69N7O6
Molecular Weight : 816.1
tert-Butyl 4-(6-((8-cyclopentyl-6-(1-isobutoxyvinyl)-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
tert-Butyl 4-(6-((8-cyclopentyl-6-(1-isobutoxyvinyl)-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
Catalogue No.:PA 43 0061079
CAS :
NA
Molecular Formula : C33H45N7O4
Molecular Weight : 603.77
