paricalcitol and its Impurities
An analog of 1,25-dihydroxyergocalciferol, which is an active form of vitamin D2 , Paricalcitol is a drug used for treating secondary hyperparathyroidism . It works by acting as an agonist at the vitamin D receptor therfore lowering the parathyroid hormone levels in the blood.Reference standards of Paricalcitol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


(1R,3R)-5-((Z)-2-((3aS,7aR)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diol
(1R,3R)-5-((Z)-2-((3aS,7aR)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diol
Catalogue No.:PA 43 12520
CAS :
NA
Molecular Formula : C27H44O3
Molecular Weight : 416.64


(1R,3R)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diol
(1R,3R)-5-((E)-2-((1R,3aS,7aR)-1-((2R,5R,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diol
Catalogue No.:PA 43 12530
CAS :
NA
Molecular Formula : C27H44O3
Molecular Weight : 416.64


(1R,3R)-5-((E)-2-((1R,3aR,7aR)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diol
(1R,3R)-5-((E)-2-((1R,3aR,7aR)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)cyclohexane-1,3-diol
Catalogue No.:PA 43 12540
CAS :
NA
Molecular Formula : C27H44O3
Molecular Weight : 416.64


(1R,3aS,7aR)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-one
(1R,3aS,7aR)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-one
Catalogue No.:PA 43 12550
CAS :
NA
Molecular Formula : C19H32O2
Molecular Weight : 292.46


(1R,3aR,7aR)-Octahydro-1-[(1R,2Z,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-one
(1R,3aR,7aR)-Octahydro-1-[(1R,2Z,4S)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-one
Catalogue No.:PA 43 0121001
CAS :
1186587-53-0
Molecular Formula : C19H32O2
Molecular Weight : 292.46


(1R,3R,E)-3-Hydroxy-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
(1R,3R,E)-3-Hydroxy-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
Catalogue No.:PA 43 0121004
CAS :
1023889-29-3
Molecular Formula : C29H46O4
Molecular Weight : 458.68


(1R,3R,E)-3-((tert-Butyldimethylsilyl)oxy)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
(1R,3R,E)-3-((tert-Butyldimethylsilyl)oxy)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
Catalogue No.:PA 43 0121005
CAS :
1206201-35-5
Molecular Formula : C35H60O4Si
Molecular Weight : 572.95


(1R,3R,Z)-3-Hydroxy-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
(1R,3R,Z)-3-Hydroxy-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
Catalogue No.:PA 43 0121006
CAS :
1023889-30-6
Molecular Formula : C29H46O4
Molecular Weight : 458.68


(1R,3R,Z)-3-((tert-Butyldimethylsilyl)oxy)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
(1R,3R,Z)-3-((tert-Butyldimethylsilyl)oxy)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexyl acetate
Catalogue No.:PA 43 0121007
CAS :
1206201-34-4
Molecular Formula : C35H60O4Si
Molecular Weight : 572.95