ponatinib and its Impurities

A multi-targeted tyrosine-kinase inhibitor, Ponatinib is used in treating chronic myeloid leukemia. Shows antiangiogenic and antineoplastic activities.Reference standards of Ponatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 16 results for ponatinib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 16 91000

Ponatinib

Ponatinib


  • Catalogue No.:PA 16 91000

  • CAS :

    943319-70-8

  • Molecular Formula : C29H27F3N6O

  • Molecular Weight : 532.56

Drug Reference Standards & Impurity Synthesis in India
PA 16 91510

3-Ethynylimidazo[1,2-b]pyridazine

3-Ethynylimidazo[1,2-b]pyridazine


  • Catalogue No.:PA 16 91510

  • CAS :

    943320-61-4

  • Molecular Formula : C8H5N3

  • Molecular Weight : 143.15

Drug Reference Standards & Impurity Synthesis in India
PA 16 91520

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-iodo-4-methylbenzamide


  • Catalogue No.:PA 16 91520

  • CAS :

    1638193-91-5

  • Molecular Formula : C16H11F3INO2

  • Molecular Weight : 433.16

Drug Reference Standards & Impurity Synthesis in India
PA 16 91530

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide

N-(4-Formyl-3-(trifluoromethyl)phenyl)-3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzamide


  • Catalogue No.:PA 16 91530

  • CAS :

    1638193-92-6

  • Molecular Formula : C24H15F3N4O2

  • Molecular Weight : 448.4

Drug Reference Standards & Impurity Synthesis in India
PA 16 91540

3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

3-Ethynyl-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 91540

  • CAS :

    957147-18-1

  • Molecular Formula : C23H24F3N3O

  • Molecular Weight : 415.45

Drug Reference Standards & Impurity Synthesis in India
PA 16 91550

3-Bromoimidazo[1,2-b]pyridazine

3-Bromoimidazo[1,2-b]pyridazine


  • Catalogue No.:PA 16 91550

  • CAS :

    18087-73-5

  • Molecular Formula : C6H4BrN3

  • Molecular Weight : 198.02

Drug Reference Standards & Impurity Synthesis in India
PA 16 91560

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl)benzamide

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 91560

  • CAS :

    943319-87-7

  • Molecular Formula : C28H25F3N6O

  • Molecular Weight : 518.53

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911000

Ponatinib N-Oxide

Ponatinib N-Oxide


  • Catalogue No.:PA 16 0911000

  • CAS :

    2227480-51-3

  • Molecular Formula : C29H27F3N6O2

  • Molecular Weight : 548.57

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911001

3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);

3,3-(Buta-1,3-diyne-1,4-diyl)bis(4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide);


  • Catalogue No.:PA 16 0911001

  • CAS :

    2097674-16-1

  • Molecular Formula : C46H46F6N6O2

  • Molecular Weight : 828.9

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911002

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic Acid


  • Catalogue No.:PA 16 0911002

  • CAS :

    1300690-48-5

  • Molecular Formula : C16H11N3O2

  • Molecular Weight : 277.28

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911003

Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate

Methyl 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoate


  • Catalogue No.:PA 16 0911003

  • CAS :

    1356385-96-0

  • Molecular Formula : C17H13N3O2

  • Molecular Weight : 291.31

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911004

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline


  • Catalogue No.:PA 16 0911004

  • CAS :

    694499-26-8

  • Molecular Formula : C13H18F3N3

  • Molecular Weight : 273.3

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911005

3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

3,5-bis(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 0911005

  • CAS :

    NA

  • Molecular Formula : C37H30F3N9O

  • Molecular Weight : 673.7

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911006

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide


  • Catalogue No.:PA 16 0911006

  • CAS :

    NA

  • Molecular Formula : C28H24F3N7O2

  • Molecular Weight : 547.54

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911007

4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

4-((4-Nitrosopiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline


  • Catalogue No.:PA 16 0911007

  • CAS :

    NA

  • Molecular Formula : C12H15F3N4O

  • Molecular Weight : 288.27

Drug Reference Standards & Impurity Synthesis in India
PA 16 0911008

Ponatinib N-beta-D-Glucuronide

Ponatinib N-beta-D-Glucuronide


  • Catalogue No.:PA 16 0911008

  • CAS :

    NA

  • Molecular Formula : C35H36BrF3N6O7

  • Molecular Weight : 789.61

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