posaconazole and its Impurities
triazole based is antifungal drug. Posaconazole is active against Candida spp. Aspergillus spp and Zygomycetes spp. It is structurally related to itraconzole.Reference standards of Posaconazole API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
1-(4-(((2R,5S)-5-((1H-1,2,4-Triazol-1-yl)methyl)-4-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methoxy)phenyl)piperazine
1-(4-(((2R,5S)-5-((1H-1,2,4-Triazol-1-yl)methyl)-4-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methoxy)phenyl)piperazine
Catalogue No.:PA 16 0821051
CAS :
NA
Molecular Formula : C24H27F2N5O2
Molecular Weight : 455.51
(2S,3R)-3-(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)pentan-2-yl formate
(2S,3R)-3-(4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)pentan-2-yl formate
Catalogue No.:PA 16 0821053
CAS :
NA
Molecular Formula : C38H42F2N8O5
Molecular Weight : 728.8
4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
Catalogue No.:PA 16 0821052
CAS :
2243785-86-4
Molecular Formula : C44H48F2N8O4
Molecular Weight : 790.92
1-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazine
1-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazine
Catalogue No.:PA 16 0821054
CAS :
454479-37-9
Molecular Formula : C24H27F2N5O2
Molecular Weight : 455.51
4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-(4-(4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-1-yl)phenoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-(4-(4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-1-yl)phenoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
Catalogue No.:PA 16 0821056
CAS :
NA
Molecular Formula : C60H69F2N13O7
Molecular Weight : 1122.29
rel-2-((2S,3S)-2-Hydroxypentan-3-yl)-4-(4-(piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
rel-2-((2S,3S)-2-Hydroxypentan-3-yl)-4-(4-(piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
Catalogue No.:PA 16 0821057
CAS :
2514953-93-4
Molecular Formula : C17H25N5O2
Molecular Weight : 331.42
