progesterone and its Impurities
A female hormone produced by the ovaries during ovulation. It is an endogenous steroid which is a precursor of other endogenous steroids like corticosteroid. In mammals it is biosynthesized from pregnenolone, which itself is derived from cholesterol. This Pregane (C21) steroid is medically used in hormone replacement therapy.Reference standards of Progesterone API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


(10R,13S,17R)-17-Acetyl-17-hydroxy-10,13-dimethyl-6-methylene-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(10R,13S,17R)-17-Acetyl-17-hydroxy-10,13-dimethyl-6-methylene-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 16 52670
CAS :
NA
Molecular Formula : C22H28O3
Molecular Weight : 340.46


(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl hex-5-enoate
(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl hex-5-enoate
Catalogue No.:PA 16 52700
CAS :
NA
Molecular Formula : C27H38O4
Molecular Weight : 426.59


(8R,9S,10R,13S,14S,17R)-17-Acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl 2,2,2-trifluoroacetate
(8R,9S,10R,13S,14S,17R)-17-Acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl 2,2,2-trifluoroacetate
Catalogue No.:PA 16 52720
CAS :
560-10-1
Molecular Formula : C23H29F3O4
Molecular Weight : 426.47


(8R,9S,10R,13S,14S)-4'-Butyl-3',10,13-trimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione
(8R,9S,10R,13S,14S)-4'-Butyl-3',10,13-trimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione
Catalogue No.:PA 16 52730
CAS :
NA
Molecular Formula : C27H38O3
Molecular Weight : 410.59


1-((17R)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-yl)ethanone
1-((17R)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-17-yl)ethanone
Catalogue No.:PA 16 52750
CAS :
NA
Molecular Formula : C23H34O4
Molecular Weight : 374.51


(17R)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-17-carbonitrile
(17R)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolane]-17-carbonitrile
Catalogue No.:PA 16 52760
CAS :
NA
Molecular Formula : C22H31NO3
Molecular Weight : 357.49


17-Acetyl-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl Diacetate
17-Acetyl-10,13-dimethyl-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl Diacetate
Catalogue No.:PA 16 52770
CAS :
NA
Molecular Formula : C25H34O5
Molecular Weight : 414.53


(9S,10R,13S,14S)-10,13-Dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione
(9S,10R,13S,14S)-10,13-Dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione
Catalogue No.:PA 16 52780
CAS :
NA
Molecular Formula : C19H26O2
Molecular Weight : 286.41


(8R,9S,10R,13S,14S,17R)-17-Acetyl-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl Dihexanoate
(8R,9S,10R,13S,14S,17R)-17-Acetyl-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diyl Dihexanoate
Catalogue No.:PA 16 52820
CAS :
139419-17-3
Molecular Formula : C33H52O5
Molecular Weight : 528.76


(8S,9S,10R,13S,14S,17S)-17-Acetyl-16-bromo-10,13-dimethyl-4,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
(8S,9S,10R,13S,14S,17S)-17-Acetyl-16-bromo-10,13-dimethyl-4,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
Catalogue No.:PAI 16 015010
CAS :
NA
Molecular Formula : C21H29BrO2
Molecular Weight : 393.36


(8S,9S,10R,13R,14S)-17-((2R,5S,E)-5-Ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
(8S,9S,10R,13R,14S)-17-((2R,5S,E)-5-Ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PAI 16 015020
CAS :
NA
Molecular Formula : C29H46O
Molecular Weight : 410.69


(10S,13S,14R,17S)-17-acetyl-10,13-Dimethyl-1,2,6,7,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
(10S,13S,14R,17S)-17-acetyl-10,13-Dimethyl-1,2,6,7,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 16 0521001
CAS :
83603-61-6
Molecular Formula : C21H28O2
Molecular Weight : 312.45


(8R,9S,10R,13S,14S,17R)-17-Acetyl-17-methoxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
(8R,9S,10R,13S,14S,17R)-17-Acetyl-17-methoxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Catalogue No.:PA 16 0521003
CAS :
13254-82-5
Molecular Formula : C22H32O3
Molecular Weight : 344.5


(8S,9S,10R,13S,14S,17S)-17-((R)-1-Hydroxyethyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
(8S,9S,10R,13S,14S,17S)-17-((R)-1-Hydroxyethyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
Catalogue No.:PAI 16 015021
CAS :
NA
Molecular Formula : C21H34O2
Molecular Weight : 318.5


(S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[a]phenanthren-17-yl)Propanoic Acid
(S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[a]phenanthren-17-yl)Propanoic Acid
Catalogue No.:PA 16 0521014
CAS :
14508-05-5
Molecular Formula : C22H32O3
Molecular Weight : 344.5