proguanil hydrochloride and its Impurities
A hydrochloride salt of Proguanil which is an antimalarial drug. It is used in combination with chloroquine. Proguanil is a rodrug of its active metabolite cycloguanil, which is an inhibitor of dihydrofolate reductase (DHFR).Reference standards of Proguanil Hydrochloride API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.