Used for the treatment of toxoplasmosis ( a parasitic disease) and cystoisosporiasis (human intestinal parasitic disease ) in combination with leucovorin. It works by inhibiting the synthesis of RNA and DNA in many species. A dihydrofolate reductase inhibitor.Reference standards of Pyrimethamine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Pyrimethamine
Catalogue No.:PA 43 01000
CAS :
Molecular Formula : C12H13ClN4
Molecular Weight : 248.71
2-(4-Chlorophenyl)-2-(2-ethyl-1,3-dioxolan-2-yl)acetonitrile
Catalogue No.:PA 43 01510
Molecular Formula : C13H14ClNO2
Molecular Weight : 251.71
Pyrimethamine E-isomer
Catalogue No.:PA 43 01520
Molecular Formula : C11H10ClNO
Molecular Weight : 207.66
Pyrimethamine Z-isomer
Catalogue No.:PA 43 01530
Pyrimethamine E/Z-Mixture
Catalogue No.:PA 43 01540
α-(4-Chlorophenyl)-α-propionylacetonitrile
Catalogue No.:PA 43 01550
(2S)-(4-chlorophenyl)(2-ethyl-1,3-dioxolan-2-yl)acetonitrile
Catalogue No.:PA 43 01560
5-(4-Chlorophenyl)-6-methylpyrimidine-2,4-diamine
Catalogue No.:PA 20 57530
Molecular Formula : C11H11ClN4
Molecular Weight : 234.68
Ethyl 2-(4-chlorophenyl)-3-oxopentanoate
Catalogue No.:PA 43 01570
Molecular Formula : C13H15ClO3
Molecular Weight : 254.71
(Z)-2-(4-Chlorophenyl)-3-hydroxypent-2-enenitrile
Catalogue No.:PA 43 01580
Catalogue No.:PA ICRS47051
Molecular Formula :
Molecular Weight : NA
Catalogue No.:PA IPIPRS 53 14
Pyrimethamine (P4200000)
Catalogue No.:PA EPP4200000
Molecular Formula : NA
Pyrimethamine (1589007)
Catalogue No.:PA USP1589007
2-Amino-5-(4-chlorophenyl)-6-ethylpyrimidin-4(1H)-one
Catalogue No.:PA 43 0011000
Molecular Formula : C12H12ClN3O
Molecular Weight : 249.7
(4-Chlorophenyl)acetonitrile
Catalogue No.:PA 43 0010030
Molecular Formula : C8H6ClN
Molecular Weight : 151.59
4-Amino-5-(4-chlorophenyl)-6-ethyl-1,2-dihydropyrimidin-2-one
Catalogue No.:PA 43 0011001
2-(4-Chlorophenyl)-3-oxobutanenitrile
Catalogue No.:PA 43 0011002
Molecular Formula : C10H8ClNO
Molecular Weight : 193.63
5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4(1H,3H)-dione
Catalogue No.:PA 43 0011003
Molecular Formula : C12H11ClN2O2
Molecular Weight : 250.68
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