ranitidine and its Impurities
An H2 histamine receptor antagonist, Ranitidine is used in the treatment of of peptic ulcer disease and gastroesophageal reflux disease It works by blocking histamine and decrasing the amount of acid released by cells of the stomach.Reference standards of Ranitidine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
 
	
			                                   
																				N,N-Dimethyl-5-[[[2-[[1-(methylthio)-2-nitroethenyl]amino]ethyl]thio]methyl]-2-furanmethanamine
N,N-Dimethyl-5-[[[2-[[1-(methylthio)-2-nitroethenyl]amino]ethyl]thio]methyl]-2-furanmethanamine
- Catalogue No.:PA 18 06540 
- CAS : - 72115-14-1
- Molecular Formula : C13H21N3O3S2 
- Molecular Weight : 331.45 
 
	
			                                   
																				N,N,N-Trimethyl-5-[[[2-[[1-(methylamino)-2-nitroethenyl]amino]ethyl]thio]methyl]-2-furanmethanaminium iodide
N,N,N-Trimethyl-5-[[[2-[[1-(methylamino)-2-nitroethenyl]amino]ethyl]thio]methyl]-2-furanmethanaminium iodide
- Catalogue No.:PA 18 06550 
- CAS : - 154018-75-4
- Molecular Formula : C14H25IN4O3S 
- Molecular Weight : 456.34 
 
	
			                                   
																				Ranitidine Related Compound A (5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine, hemi (1598507)
Ranitidine Related Compound A (5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine, hemi (1598507)
- Catalogue No.:PA USP1598507 
- CAS : - 91224-69-0
- Molecular Formula : NA 
- Molecular Weight : NA 
 
	
			                                   
																				Ranitidine Related Compound B (N,N'-bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl] (1598609)
Ranitidine Related Compound B (N,N'-bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl] (1598609)
- Catalogue No.:PA USP1598609 
- CAS : - 72126-78-4
- Molecular Formula : NA 
- Molecular Weight : NA 
 
	
			                                   
																				Ranitidine Related Compound C (N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]sulfinyl]ethyl]-N (1598700)
Ranitidine Related Compound C (N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]sulfinyl]ethyl]-N (1598700)
- Catalogue No.:PA USP1598700 
- CAS : - 73851-70-4
- Molecular Formula : NA 
- Molecular Weight : NA 
 
	
			                                   
																				5,6-Dihydro-3-(methylamino)-2H-1,4-thiazin-2-one O-[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]oxime
5,6-Dihydro-3-(methylamino)-2H-1,4-thiazin-2-one O-[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]oxime
- Catalogue No.:PA 18 0651002 
- CAS : - 112233-24-6
- Molecular Formula : C13H20N4O2S 
- Molecular Weight : 296.39 
 
	
			                                  ![N-{2-[({5-[(Dimethylamino)methyl]furan-2-yl}methyl PA 18 0651004](https://www.pharmaffiliates.com/pimages/PA180651004.jpg) 
																				N-{2-[({5-[(Dimethylamino)methyl]furan-2-yl}methyl)thio]ethyl}-N-[1-(methylamino)-2-nitrovinyl]nitrosamine
N-{2-[({5-[(Dimethylamino)methyl]furan-2-yl}methyl)thio]ethyl}-N-[1-(methylamino)-2-nitrovinyl]nitrosamine
- Catalogue No.:PA 18 0651004 
- CAS : - NA
- Molecular Formula : C13H21N5O4S 
- Molecular Weight : 343.4 
 
	
			                                  ![N-[1-({2-[({5-[(dimethylamino)methyl]furan-2-yl}me PA 18 0651005](https://www.pharmaffiliates.com/pimages/PA180651005.jpg) 
																				N-[1-({2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)thio]ethyl}amino)-2-nitrovinyl]-N-methylnitrosamine
N-[1-({2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)thio]ethyl}amino)-2-nitrovinyl]-N-methylnitrosamine
- Catalogue No.:PA 18 0651005 
- CAS : - NA
- Molecular Formula : C13H21N5O4S 
- Molecular Weight : 343.4 
 
	
			                                   
																				tert-Butyl (E)-(1-((tert-butoxycarbonyl)(2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)amino)-2-nitrovinyl)(methyl)carbamate
tert-Butyl (E)-(1-((tert-butoxycarbonyl)(2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)amino)-2-nitrovinyl)(methyl)carbamate
- Catalogue No.:PAI 18 007011 
- CAS : - NA
- Molecular Formula : C23H38N4O7S 
- Molecular Weight : 514.64 
 
	
			                                   
																				(E)-N-Methyl-N'-(2-(((5-((methylamino)methyl)furan-2-yl)methyl)thio)ethyl)-2-nitroethene-1,1-diamine
(E)-N-Methyl-N'-(2-(((5-((methylamino)methyl)furan-2-yl)methyl)thio)ethyl)-2-nitroethene-1,1-diamine
- Catalogue No.:PAI 18 007012 
- CAS : - NA
- Molecular Formula : C12H20N4O3S 
- Molecular Weight : 300.38 
 
	
			                                   
																				tert-Butyl (Z)-(1-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)amino)-2-nitrovinyl)(methyl)carbamate
tert-Butyl (Z)-(1-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)amino)-2-nitrovinyl)(methyl)carbamate
- Catalogue No.:PAI 18 007016 
- CAS : - NA
- Molecular Formula : C18H30N4O5S 
- Molecular Weight : 414.52 
 
	
			                                   
																				tert-Butyl (E)-(1-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)(nitroso)amino)-2-nitrovinyl)(methyl)carbamate
tert-Butyl (E)-(1-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)(nitroso)amino)-2-nitrovinyl)(methyl)carbamate
- Catalogue No.:PAI 18 007017 
- CAS : - NA
- Molecular Formula : C18H29N5O6S 
- Molecular Weight : 443.52 
 
	
			                                   
																				Ranitidine Hydrochloride -Impurity E (Hydrochloride Salt) (EP/BP)
N-[2-[[[5-[(Dimethyloxidoamino)methyl]furan-2-yl]methyl]sulfanyl]ethyl]-N′-methyl-2- nitroethene-1,1-diamine Hydrochloride
- Catalogue No.:PA 18 0650051 
- CAS : - 75679-05-9
- Molecular Formula : C13H23ClN4O4S 
- Molecular Weight : 366.86 

 
																				 
																				 
																				 
																				![1,1'-N-[Methylenebis(sulphanediylethylene)]bis(N'- PA STI 061450](https://www.pharmaffiliates.com/pimages/PASTI061450.jpg) 
																				 
																				 
																				 
																				 
																				![5-[(Dimethyl-d6-amino)methyl]-2-furanmethanol PA STI 033570](https://www.pharmaffiliates.com/pimages/PASTI033570.jpg) 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				![5-[[(2-Aminoethyl)thio]methyl]-N-methyl-2-furanmet PA 18 06560](https://www.pharmaffiliates.com/pimages/PA1806560.jpg) 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
																				 
 
 
 
