Ripretinib and its Impurities
Ripretinib, sold under the brand name Qinlock, is a medication for the treatment of adults with advanced gastrointestinal stromal tumor (GIST). Reference standards of Ripretinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
1-(4-Bromo-5-(7-(dimethylamino)-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea
1-(4-Bromo-5-(7-(dimethylamino)-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea
Catalogue No.:PA 18 1441001
CAS :
NA
Molecular Formula : C25H23BrFN5O2
Molecular Weight : 524.39
1-(3-(2-Bromo-4-fluoro-5-(3-phenylureido)phenyl)-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-7-yl)-1-methyl-3-phenylurea
1-(3-(2-Bromo-4-fluoro-5-(3-phenylureido)phenyl)-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-7-yl)-1-methyl-3-phenylurea
Catalogue No.:PA 18 1441002
CAS :
2657703-87-0
Molecular Formula : C31H26BrFN6O3
Molecular Weight : 629.49