risedronate sodium and its Impurities
A pyridinyl bisphosphonate drug, used for the treatment or prevention of osteoporosis in men and women. Risedronate helps in inhibiting the osteoclast-mediated bone resorption and modulates bone metabolism. An aminobisphosphonate derivative of etidronic acid. Reference standards of Risedronate Sodium API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Risedronate Sodium - Impurity A (Disodium Salt)
[(3RS,6RS and 3R,6S-meso)-2,5-Dihydroxy-2,5-dioxo-3,6-bis[(pyridin-3-yl)methyl]-1,4,2λ5,5λ5-dioxadiphosphinane-3,6-diyl]bis(Phosphonic Acid) Disodium Salt
Catalogue No.:PA 18 41010
CAS :
1486466-30-1
Molecular Formula : C14H16N2Na2O12P4
Molecular Weight : 574.16
Risedronate Related Compound A ([1-hydroxy-2-(2-pyridinyl)ethylidene]bis(phosphonic acid)) (1604621)
Risedronate Related Compound A ([1-hydroxy-2-(2-pyridinyl)ethylidene]bis(phosphonic acid)) (1604621)
Catalogue No.:PA USP1604621
CAS :
105462-23-5
Molecular Formula : NA
Molecular Weight : NA
Risedronate Related Compound B ([3,6-bis[(3-pyridinyl)methyl]-2,5-dihydroxy-2,5-dioxido-1,4,2,5-dio (1604632)
Risedronate Related Compound B ([3,6-bis[(3-pyridinyl)methyl]-2,5-dihydroxy-2,5-dioxido-1,4,2,5-dio (1604632)
Catalogue No.:PA USP1604632
CAS :
NA
Molecular Formula : NA
Molecular Weight : NA
Risedronate Sodium - Impurity A (Free Base)
[(3RS,6RS and 3R,6S-meso)-2,5-Dihydroxy-2,5-dioxo-3,6-bis[(pyridin-3-yl)methyl]-1,4,2λ5,5λ5-dioxadiphosphinane-3,6-diyl]bis(phosphonic acid)
Catalogue No.:PA 18 0410011
CAS :
1486617-90-6
Molecular Formula : C14H18N2O12P4
Molecular Weight : 530.2
Risedronate Sodium - Impurity A (Disodium Tetrahydrate Salt)
[(3RS,6RS and 3R,6S-meso)-2,5-Dihydroxy-2,5-dioxo-3,6-bis[(pyridin-3-yl)methyl]-1,4,2λ5,5λ5-dioxadiphosphinane-3,6-diyl]bis(phosphonic acid) Disodium Tetrahydrate Salt
Catalogue No.:PA 18 0410012
CAS :
NA
Molecular Formula : C14H26N2Na2O16P4
Molecular Weight : 648.23
