ritonavir and its Impurities

Ritonavir - API

Ritonavir

Ritonavir - Impurity A

(2S)-3-Methyl-2-(((methyl((2-(1-methylethyl)-1,3-thiazol-4-yl)methyl)amino)carbonyl)amino)butanoic Acid

Ritonavir - Impurity B (Freebase)

1,3-Thiazol-5-ylmethyl ((1S,2S,4S)-4-(((2S)-2-amino3-methylbutanoyl)amino)-2-hydroxy-5-phenyl-1- (phenylmethyl)pentyl)carbamate

Ritonavir - Impurity C (Freebase)

Thiazol-5-ylmethyl [(1S,2S,4S)-4-(acetylamino)-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate

Ritonavir - Impurity E

Hydroxy Ritonavir

Ritonavir - Impurity F (Freebase)

1,3-thiazol-5-ylmethyl ((1S,2S,4S)-2-hydroxy-4-((4S)-4- (1-methylethyl)-2,5-dioxoimidazolidin-1-yl)-5-phenyl-1- (phenylmethyl)pentyl)carbamate

Ritonavir - Impurity G

Ritonavir Hydroperoxide

Ritonavir - Impurity H

Thiazol-5-ylmethyl (4S,5S)-4-benzyl-5-[(2S)-2-[(4S)-4-(1-methylethyl)-2,5-dioxoimidazolidin-1-yl]-3-phenylpropyl]-2-oxooxazolidine-3-carboxylate

Ritonavir - Impurity I

2-Desisopropyl-2-ethyl Ritonavir

Ritonavir - Impurity K

Thiazol-5-ylmethyl (1S,2S,4S)-1-benzyl-2-hydroxy-4-[[(2-methylpropoxy)carbonyl]amino]-5-phenylpentyl]carbamate

Ritonavir - Impurity L (Freebase)

(2S)-3-Methyl-2-(((methyl((2-(1-methylethyl)-1,3-thiazol4-yl)methyl)amino)carbonyl)amino)-N-((1S)-2-((4S,5S)-2-oxo-4-(phenylmethyl)-1,3-oxazolidin-5-yl)-1-(phenylmethyl)ethyl)butanamide

Ritonavir - Impurity P

Ritonavir Aminoalcohol Urea

Ritonavir - Impurity Q

Thiazol-5-ylmethyl [(1S,2R,4R)-1-benzyl-2-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl]amino]-5-phenylpentyl]carbamate

Ritonavir - Impurity R

5-Epimer Ritonavir

Ritonavir - Impurity S

Thiazol-5-ylmethyl [(1S,2S,4S)-1-benzyl-4-[[(2S)-2-[[[(1S,3S,4S)-1-benzyl-3-hydroxy-5-phenyl-4-[[(thiazol-5-ylmethoxy)carbonyl]amino]pentyl]carbamoyl]amino]-3-methylbutanoyl]amino]-2-hydroxy-5-phenylpentyl]carbamate

Ritonavir - Impurity U

(1S,3S)-3-[[(2S)-3-Methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl]amino]-4-phenyl-1-[(1S)-2-phenyl-1-[[(thiazol-5-ylmethoxy)carbonyl]amino]ethyl]butyl (2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoate

Ritonavir Geo-isomer

Ritonavir Geo-isomer

Ritonavir R-Isomer

Ritonavir R-Isomer

Mixture of Hydroxyritonavir, Hydantoin aminoalcohol, Ritonavir and 4-hydroxy Isomer

Mixture of Hydroxyritonavir, Hydantoin aminoalcohol, Ritonavir and 4-hydroxy Isomer

(3S,6S,8S,9S)-8-Hydroxy-3-(1-methylethyl)-4,11-dioxo-6,9-bis(phenylmethyl)-13-(5-thiazolyl)-12-oxa-2,5,10-triazatridecanoic Acid 2,3-Dihydroxypropyl Ester

(3S,6S,8S,9S)-8-Hydroxy-3-(1-methylethyl)-4,11-dioxo-6,9-bis(phenylmethyl)-13-(5-thiazolyl)-12-oxa-2,5,10-triazatridecanoic Acid 2,3-Dihydroxypropyl Ester

N-Methyl-N-[(2-isopropyl-1,1,1,3,3,3-d6]-4-thiazolyl)methyl)amine, Hydrochloride Salt

N-Methyl-N-[(2-isopropyl-1,1,1,3,3,3-d6]-4-thiazolyl)methyl)amine, Hydrochloride Salt

N-[[N-Methyl-N-[(2-isopropyl-1,1,1,3,3,3-d6]-4-thiazolyl)methyl)amino]carbonyl-L-valine Carboxylic Acid

N-[[N-Methyl-N-[(2-isopropyl-1,1,1,3,3,3-d6]-4-thiazolyl)methyl)amino]carbonyl-L-valine Carboxylic Acid

N-[[N-Methyl-N-[(2-isopropyl-1,1,1,3,3,3-d6]-4-thiazolyl)methyl)amino]carbonyl-L-valine Methyl Ester

N-[[N-Methyl-N-[(2-isopropyl-1,1,1,3,3,3-d6]-4-thiazolyl)methyl)amino]carbonyl-L-valine Methyl Ester

Des(isopropylthiazolyl)-N-methyl Ritonavir-d6

Des(isopropylthiazolyl)-N-methyl Ritonavir-d6

Desthiazolylmethyloxycarbonyl Ritonavir-d6

Desthiazolylmethyloxycarbonyl Ritonavir-d6

Hydroxy Ritonavir-d3

Hydroxy Ritonavir-d3

Ritonavir-d6

Ritonavir-d6

Ritonavir-13C3

Ritonavir-13C3

Tipranavir-d4 β-D-Glucuronide

Tipranavir-d4 β-D-Glucuronide

(R)-Methyl 3-methyl-2-(((4-nitrophenoxy)carbonyl)amino)butanoate

(R)-Methyl 3-methyl-2-(((4-nitrophenoxy)carbonyl)amino)butanoate

(R)-Methyl 2-(3-(2-isopropylthiazol-4-yl)-3-methylureido)-3-methylbutanoate

(R)-Methyl 2-(3-(2-isopropylthiazol-4-yl)-3-methylureido)-3-methylbutanoate

Ritonavir - Impurity D

Thiazol-5-ylmethyl [(1S,2S,4S)-1-benzyl-2-hydroxy-5-phenyl-4-[[(thiazol-5-ylmethoxy)carbonyl]amino]pentyl]carbamate

Ritonavir - Impurity M

2-Methylpropyl (2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoate

Ritonavir - Impurity N

Thiazol-5-ylmethyl [(1S,3S,4S)-1-benzyl-3-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4- yl]methyl]carbamoyl]amino]butanoyl]amino]-5-phenylpentyl]carbamate

Ritonavir - Impurity O

Thiazol-5-ylmethyl [(1S,2R,4S)-1-benzyl-2-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl]amino]-5-phenylpentyl]carbamate

Ritonavir - Impurity T

(2S)-N-[(1S,2S,4S)-1-Benzyl-2-hydroxy-4-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanoyl]amino]-5-phenylpentyl]-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]amino]butanamide

Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-((ethoxycarbonyl)amino)-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-((ethoxycarbonyl)amino)-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

4-Nitrophenyl (thiazol-5-ylmethyl) Carbonate

4-Nitrophenyl (thiazol-5-ylmethyl) Carbonate

Ritonavir (ICRS1421)

Ritonavir (IPRS/10/13)-from IPC

Ritonavir for peak identification (Y0000706)

Ritonavir for peak identification (Y0000706)

Ritonavir (Y0000714)

Ritonavir (Y0000714)

Ritonavir (1604803)

Ritonavir (1604803)

Ritonavir Related Compounds Mixture (1604814)

Ritonavir Related Compounds Mixture (1604814)

5S-2-Amino-5-dibenzylamino-4-oxo-1,6-diphenylhex-2-ene

5S-2-Amino-5-dibenzylamino-4-oxo-1,6-diphenylhex-2-ene

Mixture of Ureidovaline and N-Deacylvaline Ritonavir

Mixture of Ureidovaline and N-Deacylvaline Ritonavir

Mixture of BOC-Amino Alcohol and Isobutoxycarbonyl Amino Alcohol

Mixture of BOC-Amino Alcohol and Isobutoxycarbonyl Amino Alcohol

Thiazol-5-ylmethyl ((5S,6S,8S,11S,15S,17S,18S)-5,8,15-tribenzyl-6,17-dihydroxy-11-isopropyl-3,10,13-trioxo-19-phenyl-1-(thiazol-5-yl)-2-oxa-4,9,12,14-tetraazanonadecan-18-yl)carbamate

Thiazol-5-ylmethyl ((5S,6S,8S,11S,15S,17S,18S)-5,8,15-tribenzyl-6,17-dihydroxy-11-isopropyl-3,10,13-trioxo-19-phenyl-1-(thiazol-5-yl)-2-oxa-4,9,12,14-tetraazanonadecan-18-yl)carbamate

Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-(3,3-dimethylureido)-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-(3,3-dimethylureido)-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Desthiazolylmethyloxycarbonyl Ritonavir

Desthiazolylmethyloxycarbonyl Ritonavir

2-Hydroxy-2-methylpropanethioamide

2-Hydroxy-2-methylpropanethioamide

2-Chloro-5-(chloromethyl)thiazole

2-Chloro-5-(chloromethyl)thiazole

des(Isopropylthiazolyl) Ritonavir

des(Isopropylthiazolyl) Ritonavir

Ritonavir Isoleucine Analog

Ritonavir Isoleucine Analog

Tert-butyl ((2R,4R,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Tert-butyl ((2R,4R,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Tert-butyl ((2R,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Tert-butyl ((2R,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Carbamic acid, [(1R,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 1,1-dimethylethyl ester

Carbamic acid, [(1R,3S,4S)-4-amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 1,1-dimethylethyl ester

Tert-butyl ((2S,4R,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Tert-butyl ((2S,4R,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

N-​[(1S,​3S,​4R)​-​4-​Amino-​3-​hydroxy-​5-​phenyl-​1-​(phenylmethyl)​pentyl]​-​, 1,​1-​dimethylethyl ester

N-​[(1S,​3S,​4R)​-​4-​Amino-​3-​hydroxy-​5-​phenyl-​1-​(phenylmethyl)​pentyl]​-​, 1,​1-​dimethylethyl ester

Tert-butyl ((2S,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Tert-butyl ((2S,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Thiazol-5-ylmethyl ((2R,3R,5R)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate

Thiazol-5-ylmethyl ((2R,3R,5R)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate

Ethyl ((S)-1-(((2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-(((thiazol-5-ylmethoxy)carbonyl)amino)hexan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

Ethyl ((S)-1-(((2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-(((thiazol-5-ylmethoxy)carbonyl)amino)hexan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

(4S,5S)-5-((S)-2-Amino-3-phenylpropyl)-4-benzyloxazolidin-2-one

(4S,5S)-5-((S)-2-Amino-3-phenylpropyl)-4-benzyloxazolidin-2-one

Thiazol-5-ylmethyl ((2S,3S,5R)-5-((S)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

Thiazol-5-ylmethyl ((2S,3S,5R)-5-((S)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

(((2-(2-Hydroxypropan-2-yl)thiazol-4-yl)methyl)(methyl)carbamoyl)-L-valine

(((2-(2-Hydroxypropan-2-yl)thiazol-4-yl)methyl)(methyl)carbamoyl)-L-valine

(((2-(2-Hydroperoxypropan-2-yl)thiazol-4-yl)methyl)(methyl)carbamoyl)-L-valine

(((2-(2-Hydroperoxypropan-2-yl)thiazol-4-yl)methyl)(methyl)carbamoyl)-L-valine

tert-Butyl ((S)-1-((4S,5S)-4-benzyl-2-oxooxazolidin-5-yl)-3-phenylpropan-2-yl)carbamate

tert-Butyl ((S)-1-((4S,5S)-4-benzyl-2-oxooxazolidin-5-yl)-3-phenylpropan-2-yl)carbamate

Ritonavir-D8

Ritonavir-D8

Ritonavir - Impurity J (Free Base)

1,1-Dimethylethyl ((1S,3S,4S)-3-hydroxy5-phenyl-1-(phenylmethyl)-4-((((1,3-thiazol-5-ylmethyl)oxy)carbonyl)amino)pentyl)carbamate

(((2-Isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-D-valine

(((2-Isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-D-valine

2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane

2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane

tert-Butyl ((2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate Hemisuccinate

tert-Butyl ((2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate Hemisuccinate

(2S,3S,5S)-5-Amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol

(2S,3S,5S)-5-Amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol

2-Isopropyl-4-[(N-methylamino)methyl]thiazole Hydrochloride

2-Isopropyl-4-[(N-methylamino)methyl]thiazole Hydrochloride

Phenyl (((2-isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-L-valinate

Phenyl (((2-isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-L-valinate

(((2-Isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-L-isoleucine

(((2-Isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-L-isoleucine

(((2-isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-L-valine

(((2-isopropylthiazol-4-yl)methyl)(methyl)carbamoyl)-L-valine

(phenoxycarbonyl)-L-valine

(phenoxycarbonyl)-L-valine

(S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)butanoic acid

(S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)butanoic acid

Bis(thiazol-5-ylmethyl) ((2R,5R)-1,6-diphenylhexane-2,5-diyl)dicarbamate

Bis(thiazol-5-ylmethyl) ((2R,5R)-1,6-diphenylhexane-2,5-diyl)dicarbamate

tert-butyl ((2R,4S,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

tert-butyl ((2R,4S,5R)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate

N-[[(4-Nitrophenyl)methoxy]carbonyl]-D-valine

N-[[(4-Nitrophenyl)methoxy]carbonyl]-D-valine

Ritonavir - Impurity B (Hydrochloride Salt)

Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-amino-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate Hydrochloride

Thiazol-5-ylmethyl ((2R,3S,5S)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate

Thiazol-5-ylmethyl ((2R,3S,5S)-3-hydroxy-5-((S)-2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-1,6-diphenylhexan-2-yl)carbamate

1-(2-Isopropylthiazol-4-yl)-N-((2-isopropylthiazol-4-yl)methyl)-N-methylmethanamine

1-(2-Isopropylthiazol-4-yl)-N-((2-isopropylthiazol-4-yl)methyl)-N-methylmethanamine