rolapitant and its Impurities
A selective NK1 receptor antagonist, used in the treatment of chemotherapy-induced nausea and vomiting (CINV).Reference standards of Rolapitant API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
N-((S)-1-((tert-Butyldiphenylsilyl)oxy)-2-phenylbut-3-en-2-yl)-N-(((R)-5-oxo-2-vinylpyrrolidin-2-yl)methyl)nitrous amide
N-((S)-1-((tert-Butyldiphenylsilyl)oxy)-2-phenylbut-3-en-2-yl)-N-(((R)-5-oxo-2-vinylpyrrolidin-2-yl)methyl)nitrous amide
Catalogue No.:PA 18 0640571
CAS :
NA
Molecular Formula : C33H39N3O3Si
Molecular Weight : 553.78
(5R,8S)-8-(((tert-Butyldiphenylsilyl)oxy)methyl)-7-nitroso-8-phenyl-1,7-diazaspiro[4.5]dec-9-en-2-one
(5R,8S)-8-(((tert-Butyldiphenylsilyl)oxy)methyl)-7-nitroso-8-phenyl-1,7-diazaspiro[4.5]dec-9-en-2-one
Catalogue No.:PA 18 0640572
CAS :
NA
Molecular Formula : C31H35N3O3Si
Molecular Weight : 525.72
