rosuvastatin calcium and its Impurities
Rosuvastatin Calciumis a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. It is available as a generic medication.Reference standards of Rosuvastatin Calcium API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Rosuvastatin Calcium - Impurity A
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl](methyl)amino]-6-(1-methylethyl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic Acid
Catalogue No.:PA 18 66010
CAS :
1715120-13-0
Molecular Formula : C25H34FN3O7S
Molecular Weight : 539.62
Rosuvastatin Calcium - Impurity B (Calcium Salt)
(3RS,5RS,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic Acid Calcium Salt
Catalogue No.:PA 18 66510
CAS :
NA
Molecular Formula : C44H54CaF2N6O12S2
Molecular Weight : 1001.14
2-((4R,6S)-2,2-Dimethyl-6-(((1-phenyl-1H-tetrazol-5-yl)sulfonyl)methyl)-1,3-dioxan-4-yl)-N-methoxy-N-methylacetamide
2-((4R,6S)-2,2-Dimethyl-6-(((1-phenyl-1H-tetrazol-5-yl)sulfonyl)methyl)-1,3-dioxan-4-yl)-N-methoxy-N-methylacetamide
Catalogue No.:PA 18 0661007
CAS :
1353637-12-3
Molecular Formula : C18H25N5O6S
Molecular Weight : 439.49
Rosuvastatin Calcium - Impurity K (Hemicalcium Salt)
(2Z,5S,6E)-7-[4-(4-Fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-5-hydroxyhepta-2,6-dienoic Acid Hemicalcium Salt
Catalogue No.:PA 18 0660111
CAS :
NA
Molecular Formula : C22H26FN3O5S . 1/2(Ca)
Molecular Weight : 463.52 + 1/2(40.08)
