Samidorphan and its Impurities
Samidorphan, is an opioid antagonist which in the form of olanzapine/samidorphan is used in the treatment of schizophrenia and bipolar disorder. Reference standards of Samidorphan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(4bR,8aS,9R)-11-(Cyclopropylmethyl)-4,8a-dihydroxy-6-oxo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-3-carboxylic Acid
(4bR,8aS,9R)-11-(Cyclopropylmethyl)-4,8a-dihydroxy-6-oxo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-3-carboxylic Acid
Catalogue No.:PA 19 1981001
CAS :
NA
Molecular Formula : C21H25NO5
Molecular Weight : 371.43
(4'R,4a'S,7a'R,12b'S)-3'-(Cyclopropylmethyl)-4a'-hydroxy-2',3',4',4a',5',6'-hexahydro-1'H,7a'H-spiro[[1,3]dioxolane-2,7'-[4,12]methanobenzofuro[3,2-e]isoquinoline]-9'-carboxamide
(4'R,4a'S,7a'R,12b'S)-3'-(Cyclopropylmethyl)-4a'-hydroxy-2',3',4',4a',5',6'-hexahydro-1'H,7a'H-spiro[[1,3]dioxolane-2,7'-[4,12]methanobenzofuro[3,2-e]isoquinoline]-9'-carboxamide
Catalogue No.:PA 19 1981002
CAS :
361525-83-9
Molecular Formula : C23H28N2O5
Molecular Weight : 412.49
(4R,4aS,7aR,12bS)-3-(Cyclopropylmethyl)-4a-hydroxy-7-oxo-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-9-carboxamide
(4R,4aS,7aR,12bS)-3-(Cyclopropylmethyl)-4a-hydroxy-7-oxo-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-9-carboxamide
Catalogue No.:PA 19 1981003
CAS :
421552-35-4
Molecular Formula : C21H24N2O4
Molecular Weight : 368.43
(4bR,8aS,9R)-11-Butyl-4,8a-dihydroxy-6-oxo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-3-carboxamide
(4bR,8aS,9R)-11-Butyl-4,8a-dihydroxy-6-oxo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-3-carboxamide
Catalogue No.:PA 19 1981004
CAS :
NA
Molecular Formula : C21H28N2O4
Molecular Weight : 372.47
(4bR,8aS,9R)-4,8a-Dihydroxy-11-nitroso-6-oxo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-3-carboxamide
(4bR,8aS,9R)-4,8a-Dihydroxy-11-nitroso-6-oxo-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epiminoethano)phenanthrene-3-carboxamide
Catalogue No.:PA 19 1981005
CAS :
NA
Molecular Formula : C17H19N3O5
Molecular Weight : 345.36
