Siponimod, sold under the brand name Mayzent, is a selective sphingosine-1-phosphate receptor modulator for oral use that is used for multiple sclerosis. Reference standards of Siponimod API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Siponimod
Catalogue No.:PA 19 1830000
CAS :
Molecular Formula : C29H35F3N2O3
Molecular Weight : 516.61
Siponimod Fumaric Acid Impurity
Catalogue No.:PA 19 1831000
Molecular Formula : C33H39F3N2O7
Molecular Weight : 632.68
Siponimod D11
Catalogue No.:PA STI 089204
Molecular Formula : C29H24D11F3N2O3
Molecular Weight : 527.67
1-(4-Acetyl-2-ethylbenzyl)azetidine-3-carboxylic Acid
Catalogue No.:PA 19 1831001
Molecular Formula : C15H19NO3
Molecular Weight : 261.32
(E)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)-2-hydroxyazetidine-3-carboxylic Acid
Catalogue No.:PA 19 1831002
Molecular Formula : C29H35F3N2O4
Molecular Weight : 532.6
(Z)-1-(4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic Acid
Catalogue No.:PA 19 1831003
Siponimod Dimer Impurity
Catalogue No.:PA 19 1831004
Molecular Formula : C58H70F6N4O6
Molecular Weight : 1033.21
3-((4-((E)-1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)(nitroso)amino)-2-(((1-(4-((E)-1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carbonyl)oxy)methyl)propanoic Acid
Catalogue No.:PA 19 1831005
Molecular Formula : C58H69F6N5O7
Molecular Weight : 1062.21
(E)-2-(((4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)(nitroso)amino)methyl)acrylic Acid
Catalogue No.:PA 19 1831006
Molecular Formula : C29H34F3N3O4
Molecular Weight : 545.6
Dimethyl 1,1'-(((1-oxobut-2-ene-1,3-diyl)bis(2-ethyl-4,1-phenylene))bis(methylene))(E)-bis(azetidine-3-carboxylate)
Catalogue No.:PA 19 1831007
Molecular Formula : C32H40N2O5
Molecular Weight : 532.68
Dimethyl 1,1'-(((1-oxobut-2-ene-1,3-diyl)bis(2-ethyl-4,1-phenylene))bis(methylene))(Z)-bis(azetidine-3-carboxylate)
Catalogue No.:PA 19 1831008
1-(4-(1-(((4-Cyclohexyl-3-methylbenzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic Acid
Catalogue No.:PA 19 1831009
Molecular Formula : C29H38N2O3
Molecular Weight : 462.63
(E)-2-(((4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)methyl)acrylic Acid
Catalogue No.:PA 19 1831010
(E)-3-((4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)-2-(hydroxymethyl)propanoic Acid
Catalogue No.:PA 19 1831011
Molecular Formula : C29H37F3N2O4
Molecular Weight : 534.62
3-((4-((E)-1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)-2-(((1-(4-((E)-1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carbonyl)oxy)methyl)propanoic Acid
Catalogue No.:PA 19 1831012
Molecular Weight : 1032.52
1-(4-(Hydroxymethyl)-3-vinylphenyl)ethan-1-one
Catalogue No.:PA 19 1831013
Molecular Formula : C11H12O2
Molecular Weight : 176.22
1-Cyclohexyl-4-methyl-2-(trifluoromethyl)benzene
Catalogue No.:PA 19 1831014
Molecular Formula : C14H17F3
Molecular Weight : 242.29
(E)-N-((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxamide
Catalogue No.:PA 19 1831015
Molecular Formula : C43H51F6N3O3
Molecular Weight : 771.8
Siponimod-D5
Catalogue No.:PA STI 089517
Molecular Formula : C29H30D5F3N2O3
Molecular Weight : 521.64
3-((4-Acetyl-2-ethylbenzyl)amino)-2-(hydroxymethyl)propanoic Acid
Catalogue No.:PA 19 1831016
Molecular Formula : C15H21NO4
Molecular Weight : 279.34
(E)-3-Carboxy-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine 1-oxide
Catalogue No.:PA 19 1831017
(Z)-3-((4-(1-(((4-Cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)amino)-2-(hydroxymethyl)propanoic Acid
Catalogue No.:PA 19 1831018
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