sitagliptin and its Impurities
Sitagliptin impurity B is also known as Defluoro Sitagliptin, an impurity of Sitagliptan, an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Reference standards of Sitagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(S)-3-(((4-(2-Aminoethyl)-5-(trifluoromethyl)-4H-1,2,4-triazole-3-carbonyl)oxy)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
(S)-3-(((4-(2-Aminoethyl)-5-(trifluoromethyl)-4H-1,2,4-triazole-3-carbonyl)oxy)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
Catalogue No.:PAI 19 009037
CAS :
NA
Molecular Formula : C16H15F6N5O4
Molecular Weight : 455.32
Propyl 2-(2-amino-3-(2,4,5-trifluorophenyl)propyl)-7-hydroxy-2-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)benzo[d][1,3]dioxole-5-carboxylate
Propyl 2-(2-amino-3-(2,4,5-trifluorophenyl)propyl)-7-hydroxy-2-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)benzo[d][1,3]dioxole-5-carboxylate
Catalogue No.:PA 19 0481097
CAS :
NA
Molecular Formula : C26H25F6N5O5
Molecular Weight : 601.51
3-Amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one Phosphate
3-Amino-4-(2,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one Phosphate
Catalogue No.:PA 19 0481098
CAS :
2988092-90-4
Molecular Formula : C16H19F5N5O5P
Molecular Weight : 487.32
(E)-N,N'-dicyclohexyl-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboximidamide
(E)-N,N'-dicyclohexyl-3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboximidamide
Catalogue No.:PA 19 0481100
CAS :
NA
Molecular Formula : C19H29F3N6
Molecular Weight : 398.48
