sorafenib and its Impurities

A tosylate salt of Sorafenib which is a kinase inhibitor drug. It is used for the treatment of kidney, liver and thyroid cancer. It works by inhibiting the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Reference standards of Sorafenib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 48 results for sorafenib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 46 17000

Sorafenib

Sorafenib

  • Catalogue No.:PA 46 17000

  • CAS :

    284461-73-0

  • Molecular Formula : C21H16ClF3N4O3

  • Molecular Weight : 464.82

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17510

2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid

2-(4-(4-(3-(2-Chloro-3-(Trifluoromethyl)phenyl)ureido)Phenoxy)-6-Methylpicolinamido)-4-Methylbenzenesulfonic Acid

  • Catalogue No.:PA 46 17510

  • CAS :

    NA

  • Molecular Formula : C28H22ClF3N4O6S

  • Molecular Weight : 635.01

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Drug Reference Standards & Impurity Synthesis in India
PA 19 69510

Sorafenib N-Oxide

Sorafenib N-Oxide

  • Catalogue No.:PA 19 69510

  • CAS :

    583840-03-3

  • Molecular Formula : C21H16ClF3N4O4

  • Molecular Weight : 480.82

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Drug Reference Standards & Impurity Synthesis in India
PA 19 69520

4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride

4-Chloro-N-methylpyridine-2-carboxamide Hydrochloride

  • Catalogue No.:PA 19 69520

  • CAS :

    882167-77-3

  • Molecular Formula : C7H8Cl2N2O

  • Molecular Weight : 207.06

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Drug Reference Standards & Impurity Synthesis in India
PA 19 69540

Sorafenib β-D-Glucuronide

Sorafenib β-D-Glucuronide

  • Catalogue No.:PA 19 69540

  • CAS :

    1130164-93-0

  • Molecular Formula : C27H24ClF3N4O9

  • Molecular Weight : 640.95

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Drug Reference Standards & Impurity Synthesis in India
PA 19 69550

Sorafenib Hemi-Tosylate

Sorafenib Hemi-Tosylate

  • Catalogue No.:PA 19 69550

  • CAS :

    2056030-06-7

  • Molecular Formula : C21H16ClF3N4O3 .1/2 C7H8O3S

  • Molecular Weight : 464.83

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Drug Reference Standards & Impurity Synthesis in India
PA STI 079660

Sorafenib-d3

Sorafenib-d3

  • Catalogue No.:PA STI 079660

  • CAS :

    1130115-44-4

  • Molecular Formula : C21H13D3ClF3N4O3

  • Molecular Weight : 467.84

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17580

4-Chloro-3-(trifluoromethyl)phenyl Isocyanate

4-Chloro-3-(trifluoromethyl)phenyl Isocyanate

  • Catalogue No.:PA 46 17580

  • CAS :

    327-78-6

  • Molecular Formula : C8H3ClF3NO

  • Molecular Weight : 221.56

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17590

N-Methyl-4-(4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)picolinamide

N-Methyl-4-(4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)picolinamide

  • Catalogue No.:PA 46 17590

  • CAS :

    2004659-83-8

  • Molecular Formula : C20H19N5O3

  • Molecular Weight : 377.4

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17600

Ethyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

Ethyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

  • Catalogue No.:PA 46 17600

  • CAS :

    2206827-12-3

  • Molecular Formula : C16H17N3O4

  • Molecular Weight : 315.33

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17610

Flucofuron

Flucofuron

  • Catalogue No.:PA 46 17610

  • CAS :

    370-50-3

  • Molecular Formula : C15H8Cl2F6N2O

  • Molecular Weight : 417.13

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17620

4-Chloro-N-methylpyridine-2-carboxamide

4-Chloro-N-methylpyridine-2-carboxamide

  • Catalogue No.:PA 46 17620

  • CAS :

    220000-87-3

  • Molecular Formula : C7H7ClN2O

  • Molecular Weight : 170.6

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Drug Reference Standards & Impurity Synthesis in India
PA IPIPRS 109 14

Sorafenib Tosylate (IPRS/109/14)-from IPC

Sorafenib Tosylate (IPRS/109/14)-from IPC

  • Catalogue No.:PA IPIPRS 109 14

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17630

N-Desmethyl Sorafenib

N-Desmethyl Sorafenib

  • Catalogue No.:PA 46 17630

  • CAS :

    284461-74-1

  • Molecular Formula : C20H14ClF3N4O3

  • Molecular Weight : 450.8

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17640

1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea

1,3-bis(6-Chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea

  • Catalogue No.:PA 46 17640

  • CAS :

    2514724-45-7

  • Molecular Formula : C25H14Cl2F4N2O

  • Molecular Weight : 505.29

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17660

Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib

Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib

  • Catalogue No.:PA 46 17660

  • CAS :

    2204442-52-2

  • Molecular Formula : C27H23N5O6

  • Molecular Weight : 513.51

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17650

4-(Trifluoromethoxy)phenyl Isothiocyanate

4-(Trifluoromethoxy)phenyl Isothiocyanate

  • Catalogue No.:PA 46 17650

  • CAS :

    64285-95-6

  • Molecular Formula : C8H4F3NOS

  • Molecular Weight : 219.18

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Drug Reference Standards & Impurity Synthesis in India
PA STI 079661

Sorafenib-13C,d3

Sorafenib-13C,d3

  • Catalogue No.:PA STI 079661

  • CAS :

    1210608-86-8

  • Molecular Formula : C2013CH13D3ClF3N4O3

  • Molecular Weight : 468.84

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Drug Reference Standards & Impurity Synthesis in India
PA 46 17670

4-(4-Aminophenoxy)-N-ethylpicolinamide

4-(4-Aminophenoxy)-N-ethylpicolinamide

  • Catalogue No.:PA 46 17670

  • CAS :

    284462-82-4

  • Molecular Formula : C14H15N3O2

  • Molecular Weight : 257.29

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171000

4-(Hydroxyamino)phenol

4-(Hydroxyamino)phenol

  • Catalogue No.:PA 46 0171000

  • CAS :

    3505-87-1

  • Molecular Formula : C6H7NO2

  • Molecular Weight : 125.13

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171001

Sorafenib Hydroxydemethylamine

Sorafenib Hydroxydemethylamine

  • Catalogue No.:PA 46 0171001

  • CAS :

    1012058-78-4

  • Molecular Formula : C20H13ClF3N3O4

  • Molecular Weight : 451.79

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171002

4-(4-Aminophenoxy)picolinic acid

4-(4-Aminophenoxy)picolinic acid

  • Catalogue No.:PA 46 0171002

  • CAS :

    1012058-77-3

  • Molecular Formula : C12H10N2O3

  • Molecular Weight : 230.22

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Drug Reference Standards & Impurity Synthesis in India
PA 19 0691000

4-(3-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

4-(3-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide

  • Catalogue No.:PA 19 0691000

  • CAS :

    284461-76-3

  • Molecular Formula : C21H16ClF3N4O3

  • Molecular Weight : 464.83

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Drug Reference Standards & Impurity Synthesis in India
PA 19 0691001

N-Desmethyl Sorafenib (Pyridine)-N-oxide

N-Desmethyl Sorafenib (Pyridine)-N-oxide

  • Catalogue No.:PA 19 0691001

  • CAS :

    583840-04-4

  • Molecular Formula : C20H14ClF3N4O4

  • Molecular Weight : 466.8

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Drug Reference Standards & Impurity Synthesis in India
PA 19 0691002

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea

  • Catalogue No.:PA 19 0691002

  • CAS :

    1129683-83-5

  • Molecular Formula : C14H10ClF3N2O2

  • Molecular Weight : 330.69

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171003

2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene

2-Chloro-1-isocyanato-3-(trifluoromethyl)benzene

  • Catalogue No.:PA 46 0171003

  • CAS :

    88330-63-6

  • Molecular Formula : C8H3ClF3NO

  • Molecular Weight : 221.56

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171004

N-Methyl-4-phenoxypicolinamide

N-Methyl-4-phenoxypicolinamide

  • Catalogue No.:PA 46 0171004

  • CAS :

    2004659-85-0

  • Molecular Formula : C13H12N2O2

  • Molecular Weight : 228.25

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171005

Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate

Phenyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate

  • Catalogue No.:PA 46 0171005

  • CAS :

    871555-75-8

  • Molecular Formula : C14H9ClF3NO2

  • Molecular Weight : 315.68

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171006

1-(4-Chloro-3-(trifluoromethyl)phenyl)urea

1-(4-Chloro-3-(trifluoromethyl)phenyl)urea

  • Catalogue No.:PA 46 0171006

  • CAS :

    343247-69-8

  • Molecular Formula : C8H6ClF3N2O

  • Molecular Weight : 238.59

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171007

6-Chloro-N-methyl-2-pyridinecarboxamide

6-Chloro-N-methyl-2-pyridinecarboxamide

  • Catalogue No.:PA 46 0171007

  • CAS :

    845306-04-9

  • Molecular Formula : C7H7ClN2O

  • Molecular Weight : 170.6

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171008

N-Methylpicolinamide hydrochloride

N-Methylpicolinamide hydrochloride

  • Catalogue No.:PA 46 0171008

  • CAS :

    NA

  • Molecular Formula : C7H9ClN2O

  • Molecular Weight : 172.61

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Drug Reference Standards & Impurity Synthesis in India
PAI 19 069001

Phenyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate

Phenyl (2-chloro-3-(trifluoromethyl)phenyl)carbamate

  • Catalogue No.:PAI 19 069001

  • CAS :

    2518227-67-1

  • Molecular Formula : C14H9ClF3NO2

  • Molecular Weight : 315.68

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Drug Reference Standards & Impurity Synthesis in India
PAI 19 069002

N-(2-Chloro-3-(trifluoromethyl)phenyl)-O-pivaloylhydroxylamine

N-(2-Chloro-3-(trifluoromethyl)phenyl)-O-pivaloylhydroxylamine

  • Catalogue No.:PAI 19 069002

  • CAS :

    NA

  • Molecular Formula : C12H13ClF3NO2

  • Molecular Weight : 295.69

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Drug Reference Standards & Impurity Synthesis in India
PAI 46 017001

Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

Phenyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate

  • Catalogue No.:PAI 46 017001

  • CAS :

    1129683-92-6

  • Molecular Formula : C20H17N3O4

  • Molecular Weight : 363.37

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171010

4-(4-(3-(4-Chloro-3(trifluoromethyl)phenyl)ureido)phenox yl)-n-ethylpicolinamide

4-(4-(3-(4-Chloro-3(trifluoromethyl)phenyl)ureido)phenox yl)-n-ethylpicolinamide

  • Catalogue No.:PA 46 0171010

  • CAS :

    284461-82-1

  • Molecular Formula : C22H18ClF3N4O3

  • Molecular Weight : 478.86

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171009

N-Methyl-4-(4-ureidophenoxy)picolinamide

N-Methyl-4-(4-ureidophenoxy)picolinamide

  • Catalogue No.:PA 46 0171009

  • CAS :

    1129683-88-0

  • Molecular Formula : C14H14N4O3

  • Molecular Weight : 286.29

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171011

4-Chloro-N-methyl-N-(2-(methylcarbamoyl)pyridin-4-yl)picolinamide

4-Chloro-N-methyl-N-(2-(methylcarbamoyl)pyridin-4-yl)picolinamide

  • Catalogue No.:PA 46 0171011

  • CAS :

    NA

  • Molecular Formula : C14H13ClN4O2

  • Molecular Weight : 304.73

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171012

Methyl 4-(4-aminophenoxy)picolinate

Methyl 4-(4-aminophenoxy)picolinate

  • Catalogue No.:PA 46 0171012

  • CAS :

    757251-59-5

  • Molecular Formula : C13H12N2O3

  • Molecular Weight : 244.25

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171013

Sorafenib Carboxylic Acid Methyl Ester

Sorafenib Carboxylic Acid Methyl Ester

  • Catalogue No.:PA 46 0171013

  • CAS :

    573673-43-5

  • Molecular Formula : C21H15ClF3N3O4

  • Molecular Weight : 465.81

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171014

4,4'-((((Azanediylbis(carbonyl))bis(azanediyl))bis(4,1-phenylene))bis(oxy))bis(N-methylpicolinamide)

4,4'-((((Azanediylbis(carbonyl))bis(azanediyl))bis(4,1-phenylene))bis(oxy))bis(N-methylpicolinamide)

  • Catalogue No.:PA 46 0171014

  • CAS :

    2206827-18-9

  • Molecular Formula : C28H25N7O6

  • Molecular Weight : 555.55

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171015

1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea

1-(4-Ethoxy-3-(trifluoromethyl)phenyl)-3-(2-(3-(hydroxymethyl)piperidin-1-yl)ethyl)urea

  • Catalogue No.:PA 46 0171015

  • CAS :

    1567296-47-2

  • Molecular Formula : C18H26F3N3O3

  • Molecular Weight : 389.42

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171016

N-Methyl-4-(methylamino)picolinamide

N-Methyl-4-(methylamino)picolinamide

  • Catalogue No.:PA 46 0171016

  • CAS :

    1065074-98-7

  • Molecular Formula : C8H11N3O

  • Molecular Weight : 165.2

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171017

4,6-Dichloro-N-methylpicolinamide

4,6-Dichloro-N-methylpicolinamide

  • Catalogue No.:PA 46 0171017

  • CAS :

    1379324-09-0

  • Molecular Formula : C7H6Cl2N2O

  • Molecular Weight : 205.04

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Drug Reference Standards & Impurity Synthesis in India
PA STI 089851

Sorafenib-D4

Sorafenib-D4

  • Catalogue No.:PA STI 089851

  • CAS :

    1207560-07-3

  • Molecular Formula : C21H12D4ClF3N4O3

  • Molecular Weight : 468.85

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Drug Reference Standards & Impurity Synthesis in India
PA EP Y0002233

Sorafenib Impurity H (Y0002233)

Sorafenib Impurity H (Y0002233)

  • Catalogue No.:PA EP Y0002233

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171018

2,6-Dichloro-4-(hydroxyamino)phenol

2,6-Dichloro-4-(hydroxyamino)phenol

  • Catalogue No.:PA 46 0171018

  • CAS :

    2497300-82-8

  • Molecular Formula : C6H5Cl2NO2

  • Molecular Weight : 194.01

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Drug Reference Standards & Impurity Synthesis in India
PA 46 0171019

2,6-Dichloro-4-nitrosophenol

2,6-Dichloro-4-nitrosophenol

  • Catalogue No.:PA 46 0171019

  • CAS :

    17277-19-9

  • Molecular Formula : C6H3Cl2NO2

  • Molecular Weight : 192

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Drug Reference Standards & Impurity Synthesis in India
PA BSC 0174601070

Sorafenib (BSC)

Sorafenib (BSC)

  • Catalogue No.:PA BSC 0174601070

  • CAS :

    284461-73-0 (BSC)

  • Molecular Formula : C21H16ClF3N4O3

  • Molecular Weight : 464.82

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