Sparsentan and its Impurities
Sparsentan, sold under the brand name Filspari. A medication used to reduce the levels of protein in urine in patients with poor kidney function. Reference standards of Sparsentan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
N-(4,5-Dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-4'-(hydroxymethyl)-N-(methoxymethyl)-[1,1'-biphenyl]-2-sulfonamide
N-(4,5-Dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-4'-(hydroxymethyl)-N-(methoxymethyl)-[1,1'-biphenyl]-2-sulfonamide
Catalogue No.:PA 19 2311001
CAS :
1098924-76-5
Molecular Formula : C23H28N2O6S
Molecular Weight : 460.55
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-N-(methoxymethyl)-[1,1'-biphenyl]-2-sulfonamide
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-(ethoxymethyl)-N-(methoxymethyl)-[1,1'-biphenyl]-2-sulfonamide
Catalogue No.:PA 19 2311006
CAS :
1026355-73-6
Molecular Formula : C34H44N4O6S
Molecular Weight : 636.81
Ethyl 2'-(N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)sulfamoyl)-2-(ethoxymethyl)-[1,1'-biphenyl]-4-carboxylate
Ethyl 2'-(N-(4,5-dimethylisoxazol-3-yl)-N-(methoxymethyl)sulfamoyl)-2-(ethoxymethyl)-[1,1'-biphenyl]-4-carboxylate
Catalogue No.:PA 19 2311007
CAS :
1247868-68-3
Molecular Formula : C25H30N2O7S
Molecular Weight : 502.58
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-formyl-[1,1'-biphenyl]-2-sulfonamide
4'-((2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-formyl-[1,1'-biphenyl]-2-sulfonamide
Catalogue No.:PA 19 2311008
CAS :
254737-96-7
Molecular Formula : C30H34N4O5S
Molecular Weight : 562.69
