spiramycin and its Impurities
A macrolide antibiotic and antiparasitic drug, Siramycin is used in the treatment of arasotic diseases like toxoplasmosis and other infections caused in the soft tissues.Reference standards of Spiramycin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Spiramycin - Impurity B
(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[[3,6-Dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3- (dimethylamino)-β-D-glucopyranosyl]oxy]-4-hydroxy-7-(2-hydroxyethyl)-5-methoxy-9,16-dimethyl-10-[[2,3,4,6-tetradeoxy-4-(dimethylamino)-β-D-erythro-hexopyranosyl]oxy]oxacyclohexadeca-11,13-dien-2-one
Catalogue No.:PA 19 73020
CAS :
249930-66-3
Molecular Formula : C43H76N2O14
Molecular Weight : 845.08
2’-O-Acetyl-4’’-O-tert-butyldimethylsilylspiramycin I 3,18-(O-tert-Butyldimethylsilyl)acetal
2’-O-Acetyl-4’’-O-tert-butyldimethylsilylspiramycin I 3,18-(O-tert-Butyldimethylsilyl)acetal
Catalogue No.:PA 19 73540
CAS :
96405-32-2
Molecular Formula : C57H104N2O15Si2
Molecular Weight : 1113.6
2’-O-Acetyl-4’’-O-tert-butyldimethylsilyl-4’’’-de-N-methylspiramycin I 3,18-(O-tert-Butyldimethylsilyl)acetal
2’-O-Acetyl-4’’-O-tert-butyldimethylsilyl-4’’’-de-N-methylspiramycin I 3,18-(O-tert-Butyldimethylsilyl)acetal
Catalogue No.:PA 19 73550
CAS :
96405-33-3
Molecular Formula : C56H102N2O15Si2
Molecular Weight : 1099.58
