spironolactone and its Impurities

Spironolactone is used for the treatment of heart failures and kidney diseases. It is metabolised in liver and major metabolites of spironolactone are 7α-TMS,6β-OH-7α-TMS and canrenone,. Reference standards of Spironolactone API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 45 results for spironolactone Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 19 18000

Spironolactone

Spironolactone

  • Catalogue No.:PA 19 18000

  • CAS :

    52-01-7

  • Molecular Formula : C24H32O4S

  • Molecular Weight : 416.57

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18010

Spironolactone - Impurity A

Δ20-Spironolactone

  • Catalogue No.:PA 19 18010

  • CAS :

    132458-33-4

  • Molecular Formula : C24H30O4S

  • Molecular Weight : 414.56

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PA 19 18030

Spironolactone - Impurity C

Aldone

  • Catalogue No.:PA 19 18030

  • CAS :

    976-70-5

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.47

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18040

Spironolactone - Impurity D

Disulfanyl Spironolactone

  • Catalogue No.:PA 19 18040

  • CAS :

    NA

  • Molecular Formula : C24H32O4S2

  • Molecular Weight : 448.64

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PA 19 18050

Spironolactone - Impurity E

7β-Spironolactone

  • Catalogue No.:PA 19 18050

  • CAS :

    33784-05-3

  • Molecular Formula : C24H32O4S

  • Molecular Weight : 416.57

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18060

Spironolactone - Impurity F

Canrenone

  • Catalogue No.:PA 19 18060

  • CAS :

    976-71-6

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18090

Spironolactone - Impurity I

S-[17α-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en-7α-yl] Ethanethioate

  • Catalogue No.:PA 19 18090

  • CAS :

    NA

  • Molecular Formula : C24H36O4S

  • Molecular Weight : 420.61

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18510

(2'R,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'(4'H)-one

(2'R,8R,9S,10R,13S,14S)-3-Methoxy-10,13-dimethyl-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'(4'H)-one

  • Catalogue No.:PA 19 18510

  • CAS :

    NA

  • Molecular Formula : C23H32O3

  • Molecular Weight : 356.5

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18520

(2'S,8R,9S,10R,13S,14S)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione

(2'S,8R,9S,10R,13S,14S)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione

  • Catalogue No.:PA 19 18520

  • CAS :

    NA

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

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Drug Reference Standards & Impurity Synthesis in India
PA STI 004940

Althiazide-d5

Althiazide-d5

  • Catalogue No.:PA STI 004940

  • CAS :

    1329837-71-9

  • Molecular Formula : C11H9D5ClN3O4S3

  • Molecular Weight : 388.93

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Drug Reference Standards & Impurity Synthesis in India
PA STI 079750

Spironolactone-d6 (Major)

Spironolactone-d6 (Major)

  • Catalogue No.:PA STI 079750

  • CAS :

    NA

  • Molecular Formula : C24H26D6O4S

  • Molecular Weight : 422.61

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Drug Reference Standards & Impurity Synthesis in India
PA STI 079760

Spironolactone-d3

Spironolactone-d3

  • Catalogue No.:PA STI 079760

  • CAS :

    NA

  • Molecular Formula : C24H29D3O4S

  • Molecular Weight : 419.59

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PA STI 082790

7α-Thiomethyl Spironolactone-d7 (Major)

7α-Thiomethyl Spironolactone-d7 (Major)

  • Catalogue No.:PA STI 082790

  • CAS :

    NA

  • Molecular Formula : C23H25D7O3S

  • Molecular Weight : 395.61

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18020

Spironolactone - Impurity B

4-Bromospironolactone

  • Catalogue No.:PA 19 18020

  • CAS :

    NA

  • Molecular Formula : C24H31BrO4S

  • Molecular Weight : 495.47

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18070

Spironolactone - Impurity G

6β-Hydroxy-spironolactone

  • Catalogue No.:PA 19 18070

  • CAS :

    880106-10-5

  • Molecular Formula : C24H32O5S

  • Molecular Weight : 432.58

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18080

Spironolactone - Impurity H

(2'S)-Spiro[androst-4,6-diene-17,2'-oxiran]-3-one

  • Catalogue No.:PA 19 18080

  • CAS :

    53866-24-3

  • Molecular Formula : C20H26O2

  • Molecular Weight : 298.43

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Drug Reference Standards & Impurity Synthesis in India
PA ICRS49241

Spironolactone (ICRS49241)

Spironolactone (ICRS49241)

  • Catalogue No.:PA ICRS49241

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA JP0217

Spironolactone (JP 0217)

Spironolactone (JP 0217)

  • Catalogue No.:PA JP0217

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPS1200000

Spironolactone (S1200000)

Spironolactone (S1200000)

  • Catalogue No.:PA EPS1200000

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA EPY0001295

Spironolactone for system suitability (Y0001295)

Spironolactone for system suitability (Y0001295)

  • Catalogue No.:PA EPY0001295

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1619006

Spironolactone (1619006)

Spironolactone (1619006)

  • Catalogue No.:PA USP1619006

  • CAS :

    52-01-7

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1619017

Spironolactone Related Compound A (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (1619017)

Spironolactone Related Compound A (Canrenone (3-Oxo-17-alpha-pregna-4,6-diene-21, 17-carbolactone)) (1619017)

  • Catalogue No.:PA USP1619017

  • CAS :

    976-71-6

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1619028

Spironolactone Related Compound B ((2'R)-7alpha-(Acetylthio)-5'H-spiro[androst-4-ene-17,2'-furan]-3 (1619028)

Spironolactone Related Compound B ((2'R)-7alpha-(Acetylthio)-5'H-spiro[androst-4-ene-17,2'-furan]-3 (1619028)

  • Catalogue No.:PA USP1619028

  • CAS :

    132458-33-4

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1619039

Spironolactone Related Compound C ((2'R)-3',4'-Dihydro-5'H-spiro[androst-4-ene-17,2'-furan]-3,5'-di (1619039)

Spironolactone Related Compound C ((2'R)-3',4'-Dihydro-5'H-spiro[androst-4-ene-17,2'-furan]-3,5'-di (1619039)

  • Catalogue No.:PA USP1619039

  • CAS :

    976-70-5

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA USP1619040

Spironolactone Related Compound D ((2'R)-7alpha-(Acetyldisulfanyl)-3',4'-dihydro-5'H-spiro[androst- (1619040)

Spironolactone Related Compound D ((2'R)-7alpha-(Acetyldisulfanyl)-3',4'-dihydro-5'H-spiro[androst- (1619040)

  • Catalogue No.:PA USP1619040

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1619051

Spironolactone Epimer Mixture (7-Epispironolactone approximately 56% and Spironolactone approximate (1619051)

Spironolactone Epimer Mixture (7-Epispironolactone approximately 56% and Spironolactone approximate (1619051)

  • Catalogue No.:PA USP1619051

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA USP1619094

Spironolactone Related Compound I (S-[17alpha-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en-7alpha-yl (1619094)

Spironolactone Related Compound I (S-[17alpha-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en-7alpha-yl (1619094)

  • Catalogue No.:PA USP1619094

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA BP306RB

spironolactone (306RB)

spironolactone (306RB)

  • Catalogue No.:PA BP306RB

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 19 18530

Spironolactone Epimer Mixture

Spironolactone Epimer Mixture

  • Catalogue No.:PA 19 18530

  • CAS :

    NA

  • Molecular Formula : C24H32O4S

  • Molecular Weight : 416.58

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Drug Reference Standards & Impurity Synthesis in India
PAI 19 018001

(8R,9S,10R,13S,14S,17S)-17-Hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

(8R,9S,10R,13S,14S,17S)-17-Hydroxy-17-(3-hydroxyprop-1-yn-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

  • Catalogue No.:PAI 19 018001

  • CAS :

    55542-26-2

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.48

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PAI 19 018002

(8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-(3-hydroxyprop-1-en-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

(8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-(3-hydroxyprop-1-en-1-yl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

  • Catalogue No.:PAI 19 018002

  • CAS :

    NA

  • Molecular Formula : C22H32O3

  • Molecular Weight : 344.5

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Drug Reference Standards & Impurity Synthesis in India
PAI 19 018003

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione

  • Catalogue No.:PAI 19 018003

  • CAS :

    52845-59-7

  • Molecular Formula : C22H28O3

  • Molecular Weight : 340.46

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Drug Reference Standards & Impurity Synthesis in India
PAI 19 018004

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione

(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H)-dione

  • Catalogue No.:PAI 19 018004

  • CAS :

    NA

  • Molecular Formula : C22H26O3

  • Molecular Weight : 338.45

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PAI 19 018005

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate

  • Catalogue No.:PAI 19 018005

  • CAS :

    NA

  • Molecular Formula : C24H34O4

  • Molecular Weight : 386.53

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PAI 19 018006

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate

  • Catalogue No.:PAI 19 018006

  • CAS :

    NA

  • Molecular Formula : C24H36O4

  • Molecular Weight : 388.55

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PAI 19 018007

(3S,8R,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one

(3S,8R,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one

  • Catalogue No.:PAI 19 018007

  • CAS :

    NA

  • Molecular Formula : C22H30O3

  • Molecular Weight : 342.48

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PAI 19 018008

(3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]androst-5-en-17-one

(3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]androst-5-en-17-one

  • Catalogue No.:PAI 19 018008

  • CAS :

    42151-23-5

  • Molecular Formula : C25H42O2Si

  • Molecular Weight : 402.69

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PAI 19 018009

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate

Ethyl 3-((3S,8R,9S,10R,13S,14S,17S)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propiolate

  • Catalogue No.:PAI 19 018009

  • CAS :

    NA

  • Molecular Formula : C30H48O4Si

  • Molecular Weight : 500.8

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PAI 19 018010

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate

Ethyl (E)-3-((3S,8R,9S,10R,13S,14S,17R)-3-((tert-butyldimethylsilyl)oxy)-17-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)acrylate

  • Catalogue No.:PAI 19 018010

  • CAS :

    NA

  • Molecular Formula : C30H50O4Si

  • Molecular Weight : 502.81

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PAI 19 018011

(3S,8R,9S,10R,13S,14S,17R)-3-((tert-Butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one

(3S,8R,9S,10R,13S,14S,17R)-3-((tert-Butyldimethylsilyl)oxy)-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-5'-one

  • Catalogue No.:PAI 19 018011

  • CAS :

    NA

  • Molecular Formula : C28H44O3Si

  • Molecular Weight : 456.74

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PA 19 0181000

7α-Thiomethyl spironolactone

7α-Thiomethyl spironolactone

  • Catalogue No.:PA 19 0181000

  • CAS :

    38753-77-4

  • Molecular Formula : C23H32O3S

  • Molecular Weight : 388.57

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PA 19 0181001

7α-Thio spironolactone

7α-Thio spironolactone

  • Catalogue No.:PA 19 0181001

  • CAS :

    38753-76-3

  • Molecular Formula : C22H30O3S

  • Molecular Weight : 374.54

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PA IPRS 36 18

Spironolactone (IPRS/36/18)-from IPC

Spironolactone (IPRS/36/18)-from IPC

  • Catalogue No.:PA IPRS 36 18

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA 19 0181002

6beta-Hydroxy-7alpha-thiomethylspirolactone

6beta-Hydroxy-7alpha-thiomethylspirolactone

  • Catalogue No.:PA 19 0181002

  • CAS :

    42219-60-3

  • Molecular Formula : C23H32O4S

  • Molecular Weight : 404.57

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PA 19 0181003

(8R,9S,10R,13S,14S)-3,3-Diethoxy-10,13-dimethyl-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one

(8R,9S,10R,13S,14S)-3,3-Diethoxy-10,13-dimethyl-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one

  • Catalogue No.:PA 19 0181003

  • CAS :

    NA

  • Molecular Formula : C23H36O3

  • Molecular Weight : 360.54

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