Sunvozertinib and its Impurities

Sunvozertinib also known as Zegfrovy is an oral, irreversible, mutant-selective epidermal growth factor receptor tyrosine kinase inhibitor. It is used to treat adults with locally advanced or metastatic non-small-cell lung cancer. Reference standards of Sunvozertinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.