tiotropium bromide and its Impurities

A muscarinic receptor antagonist, used in the treatment of chronic obstructive pulmonary disease (COPD). A long acting anticholinergic bronchodilator .Reference standards of Tiotropium Bromide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 20 results for tiotropium bromide Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 20 66000

Tiotropium Bromide

Tiotropium Bromide

  • Catalogue No.:PA 20 66000

  • CAS :

    136310-93-5

  • Molecular Formula : C19H22BrNO4S2

  • Molecular Weight : 472.42

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66010

Tiotropium Bromide - Impurity A

Hydroxy[di(thiophen-2-yl)]acetic Acid

  • Catalogue No.:PA 20 66010

  • CAS :

    4746-63-8

  • Molecular Formula : C10H8O3S2

  • Molecular Weight : 240.30

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66020

Scopine di(2-thienylglycolate

Scopine di(2-thienylglycolate

  • Catalogue No.:PA 20 66020

  • CAS :

    136310-64-0

  • Molecular Formula : C18H19NO4S2

  • Molecular Weight : 377.48

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66030

Tiotropium Bromide - Impurity C

(1R,3S,5S)-3-[(2-Hydroxy-2,2-dithiophen-2-ylacetyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-6-ene Bromide

  • Catalogue No.:PA 20 66030

  • CAS :

    136310-95-7

  • Molecular Formula : C19H22BrNO3S2

  • Molecular Weight : 456.42

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66040

Tiotropium Bromide - Impurity D

(1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 2-hydroxy-2,2-dithiophen-2-ylacetate

  • Catalogue No.:PA 20 66040

  • CAS :

    136310-66-2

  • Molecular Formula : C18H19NO3S2

  • Molecular Weight : 361.48

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66050

Tiotropium Bromide - Impurity E

Methyl hydroxy[di(thiophen-2-yl)]Acetate

  • Catalogue No.:PA 20 66050

  • CAS :

    26447-85-8

  • Molecular Formula : C11H10O3S2

  • Molecular Weight : 254.33

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66060

Tiotropium Bromide - Impurity F

Di(thiophen-2-yl)methanone

  • Catalogue No.:PA 20 66060

  • CAS :

    704-38-1

  • Molecular Formula : C9H6OS2

  • Molecular Weight : 194.27

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66070

Tiotropium Bromide - Impurity G

N-Methylscopine Bromide

  • Catalogue No.:PA 20 66070

  • CAS :

    1508-46-9

  • Molecular Formula : C9H16BrNO2

  • Molecular Weight : 250.13

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66080

Tiotropium Bromide - Impurity H

(1s,3RS,4RS,5RS,7SR)-4-Hydroxy-6,6-dimethyl-2-oxa-6-azoniatricyclo[3.3.1.03,7]nonane Bromide

  • Catalogue No.:PA 20 66080

  • CAS :

    845870-40-8

  • Molecular Formula : C9H16BrNO2

  • Molecular Weight : 250.13

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66090

Tiotropium Bromide - Impurity I

(1R,2R,4S,5S,7r)-7-[(2-Hydroxy-2,2-dithiophen-2-ylacetyl)oxy]-9,9-dimethyl-3- oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide

  • Catalogue No.:PA 20 66090

  • CAS :

    136521-48-7

  • Molecular Formula : C19H22BrNO4S2

  • Molecular Weight : 472.42

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66100

Tiotropium Bromide - Impurity J

(1R,3s,5S,8s)-8-(Chloromethyl)-3-[(2-hydroxy-2,2-dithiophen-2-ylacetyl)oxy]-8- methyl-8-azoniabicyclo[3.2.1]oct-6-ene Chloride

  • Catalogue No.:PA 20 66100

  • CAS :

    NA

  • Molecular Formula : C19H21Cl2NO3S2

  • Molecular Weight : 446.41

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Drug Reference Standards & Impurity Synthesis in India
PA 20 66110

Tiotropium Bromide - Impurity K

(1R,2R,4S,5S,7s)-9-Acetyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy- 2,2-dithiophen-2-ylacetate

  • Catalogue No.:PA 20 66110

  • CAS :

    NA

  • Molecular Formula : C19H19NO5S2

  • Molecular Weight : 405.49

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Drug Reference Standards & Impurity Synthesis in India
PA 20 0661006

8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-ol

8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-ol

  • Catalogue No.:PA 20 0661006

  • CAS :

    20513-09-1

  • Molecular Formula : C8H13NO

  • Molecular Weight : 139.2

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Drug Reference Standards & Impurity Synthesis in India
PA 20 0660101

Tiotropium Bromide - Impurity J (Iodide Salt)

(1R,3s,5S,8s)-8-(Chloromethyl)-3-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-8-ium iodide

  • Catalogue No.:PA 20 0660101

  • CAS :

    NA

  • Molecular Formula : C19H21ClINO3S2

  • Molecular Weight : 537.86

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Drug Reference Standards & Impurity Synthesis in India
PA 20 0660011

Tiotropium Bromide - Impurity A (Sodium Salt)

Di-2-Thienylglycolic Acid Sodium Salt

  • Catalogue No.:PA 20 0660011

  • CAS :

    877467-46-4

  • Molecular Formula : C10H8NaO3S2

  • Molecular Weight : 263.28

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Drug Reference Standards & Impurity Synthesis in India
PA USP 1667574

Tiotropium Bromide (1667574)

Tiotropium Bromide (1667574)

  • Catalogue No.:PA USP 1667574

  • CAS :

    136310-93-5

  • Molecular Formula : NA

  • Molecular Weight : NA

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Drug Reference Standards & Impurity Synthesis in India
PA 20 0661012

Methyl-2-(thien-2-yl)-2-(thien-3-yl)glycolate

Methyl-2-(thien-2-yl)-2-(thien-3-yl)glycolate

  • Catalogue No.:PA 20 0661012

  • CAS :

    28748-67-6

  • Molecular Formula : C11H10O3S2

  • Molecular Weight : 254.32

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Drug Reference Standards & Impurity Synthesis in India
PA 20 0661013

Methyl 2-hydroxy-2,2-di(thiophen-3-yl)acetate

Methyl 2-hydroxy-2,2-di(thiophen-3-yl)acetate

  • Catalogue No.:PA 20 0661013

  • CAS :

    28540-31-0

  • Molecular Formula : C11H10O3S2

  • Molecular Weight : 254.32

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Drug Reference Standards & Impurity Synthesis in India
PA 20 0661014

α-Hydroxy-α-3-thienyl-2-thiopheneacetic Acid 9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester

α-Hydroxy-α-3-thienyl-2-thiopheneacetic Acid 9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester

  • Catalogue No.:PA 20 0661014

  • CAS :

    783273-13-2

  • Molecular Formula : C18H19NO4S2

  • Molecular Weight : 377.47

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Drug Reference Standards & Impurity Synthesis in India
PA 20 0661015

rel-(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

rel-(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate

  • Catalogue No.:PA 20 0661015

  • CAS :

    736108-96-6

  • Molecular Formula : C18H19NO3S2

  • Molecular Weight : 361.47

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