Tiotropium and its Impurities

Tiotropium is used for maintenance treatment of chronic obstructive pulmonary disease. It is sold under the brandname Spiriva.Reference standards of Tiotropium API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 27 results for Tiotropium Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 20 66510

(R)-Quinucldin-3-yl hydroxybis(2-thienyl)acetate

(R)-Quinucldin-3-yl hydroxybis(2-thienyl)acetate


  • Catalogue No.:PA 20 66510

  • CAS :

    320347-97-5

  • Molecular Formula : C17H19NO3S2

  • Molecular Weight : 349.47

Drug Reference Standards & Impurity Synthesis in India
PA 20 66520

Iso Tiotropium Bromide

Iso Tiotropium Bromide


  • Catalogue No.:PA 20 66520

  • CAS :

    136431-94-2

  • Molecular Formula : C19H22BrNO4S2

  • Molecular Weight : 472.42

Drug Reference Standards & Impurity Synthesis in India
PA 20 66530

(2R,3aR,5S,6S,6aS)-6-(Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium Bromide

(2R,3aR,5S,6S,6aS)-6-(Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium Bromide


  • Catalogue No.:PA 20 66530

  • CAS :

    NA

  • Molecular Formula : C19H22BrNO4S2

  • Molecular Weight : 472.42

Drug Reference Standards & Impurity Synthesis in India
PA 20 66540

(S)-Aclidinium Bromide

(S)-Aclidinium Bromide


  • Catalogue No.:PA 20 66540

  • CAS :

    320346-78-9

  • Molecular Formula : C26H30BrNO4S2

  • Molecular Weight : 564.55

Drug Reference Standards & Impurity Synthesis in India
PA 20 66550

Ethyl 2-Hydroxy-2,2-di(thiophen-2-yl)Acetate

Ethyl 2-Hydroxy-2,2-di(thiophen-2-yl)Acetate


  • Catalogue No.:PA 20 66550

  • CAS :

    28569-88-2

  • Molecular Formula : C12H12O3S2

  • Molecular Weight : 268.35

Drug Reference Standards & Impurity Synthesis in India
PA 20 66560

(2S,3aS,5R,6R,6aR)-4-Methylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-6-yl 2-hydroxy-2,2-di(thiophen-2-yl)Acetate

(2S,3aS,5R,6R,6aR)-4-Methylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-6-yl 2-hydroxy-2,2-di(thiophen-2-yl)Acetate


  • Catalogue No.:PA 20 66560

  • CAS :

    1459721-06-2

  • Molecular Formula : C18H19NO4S2

  • Molecular Weight : 377.48

Drug Reference Standards & Impurity Synthesis in India
PA STI 048700

(1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-d3-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide_x0000_

(1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-d3-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide_x0000_


  • Catalogue No.:PA STI 048700

  • CAS :

    NA

  • Molecular Formula : C19H19D3BrNO3S2

  • Molecular Weight : 459.44

Drug Reference Standards & Impurity Synthesis in India
PA STI 051790

7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide-d6

7-[(Hydroxy-2-thienyl-3-thienylacetyl)oxy]-9,9-dimethyl-3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide-d6


  • Catalogue No.:PA STI 051790

  • CAS :

    NA

  • Molecular Formula : C19H16D6NO4S2

  • Molecular Weight : 398.55

Drug Reference Standards & Impurity Synthesis in India
PA STI 083300

Tiotropium-d3 Bromide

Tiotropium-d3 Bromide


  • Catalogue No.:PA STI 083300

  • CAS :

    1127226-56-5

  • Molecular Formula : C19H19D3BrNO4S2

  • Molecular Weight : 475.43

Drug Reference Standards & Impurity Synthesis in India
PA STI 083310

Tiotropium-d5 Bromide

Tiotropium-d5 Bromide


  • Catalogue No.:PA STI 083310

  • CAS :

    1229646-72-3

  • Molecular Formula : C19H17D5BrNO4S2

  • Molecular Weight : 477.45

Drug Reference Standards & Impurity Synthesis in India
PA EPY0001179

Tiotropium impurity mixture (Y0001179)

Tiotropium impurity mixture (Y0001179)


  • Catalogue No.:PA EPY0001179

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA EPY0001188

Tiotropium bromide monohydrate (Y0001188)

Tiotropium bromide monohydrate (Y0001188)


  • Catalogue No.:PA EPY0001188

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA EPY0001189

Tiotropium for system suitability (Y0001189)

Tiotropium for system suitability (Y0001189)


  • Catalogue No.:PA EPY0001189

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA EPY0001216

Tiotropium impurity F (Y0001216)

Tiotropium impurity F (Y0001216)


  • Catalogue No.:PA EPY0001216

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA STI 083301

Tiotropium-d3 Iodide

Tiotropium-d3 Iodide


  • Catalogue No.:PA STI 083301

  • CAS :

    NA

  • Molecular Formula : C19H19D3INO4S2

  • Molecular Weight : 522.43

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661001

(2S,3aS,5R,6R,6aR)-6-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

(2S,3aS,5R,6R,6aR)-6-(2-hydroxy-2,2-di(thiophen-2-yl)acetoxy)-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide


  • Catalogue No.:PA 20 0661001

  • CAS :

    NA

  • Molecular Formula : C19H22BrNO4S2

  • Molecular Weight : 472.41

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661007

2,3-Dibromothiophene

2,3-Dibromothiophene


  • Catalogue No.:PA 20 0661007

  • CAS :

    3140-93-0

  • Molecular Formula : C4H2Br2S

  • Molecular Weight : 241.93

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661008

Propan-2-one compound with (1R,3s,5S,6S,7R)-8-methyl-8-azabicyclo[3.2.1]octane-3,6,7-triol (1:1)

Propan-2-one compound with (1R,3s,5S,6S,7R)-8-methyl-8-azabicyclo[3.2.1]octane-3,6,7-triol (1:1)


  • Catalogue No.:PA 20 0661008

  • CAS :

    NA

  • Molecular Formula : C11H21NO4

  • Molecular Weight : 231.29

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661009

Rac-Trans-4-Hydroxy tolvaptan

Rac-Trans-4-Hydroxy tolvaptan


  • Catalogue No.:PA 20 0661009

  • CAS :

    926035-34-9

  • Molecular Formula : C26H25ClN2O4

  • Molecular Weight : 464.95

Drug Reference Standards & Impurity Synthesis in India
PA STI 088999

2-Hydroxy-2-(thiophen-2-yl)-2-(thiophen-2-yl-d3)acetic acid

2-Hydroxy-2-(thiophen-2-yl)-2-(thiophen-2-yl-d3)acetic acid


  • Catalogue No.:PA STI 088999

  • CAS :

    NA

  • Molecular Formula : C10H5D3O3S2

  • Molecular Weight : 243.31

Drug Reference Standards & Impurity Synthesis in India
PA STI 089000

2-Hydroxy-2,2-bis(thiophen-2-yl-d3)acetic acid

2-Hydroxy-2,2-bis(thiophen-2-yl-d3)acetic acid


  • Catalogue No.:PA STI 089000

  • CAS :

    NA

  • Molecular Formula : C10H2D6O3S2

  • Molecular Weight : 246.33

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661002

Rel-(2R,3aS,5R,6R,6aR)-6-hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide

Rel-(2R,3aS,5R,6R,6aR)-6-hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4-ium bromide


  • Catalogue No.:PA 20 0661002

  • CAS :

    1044148-31-3

  • Molecular Formula : C9H16BrNO2

  • Molecular Weight : 250.14

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661003

Iso Tiotropium Bromide Impurity

Iso Tiotropium Bromide Impurity


  • Catalogue No.:PA 20 0661003

  • CAS :

    1978292-75-9

  • Molecular Formula : C19H22BrNO4S2

  • Molecular Weight : 472.41

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661004

(1R,3s,5S,6S,7R)-6,7-Dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl acetate

(1R,3s,5S,6S,7R)-6,7-Dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl acetate


  • Catalogue No.:PA 20 0661004

  • CAS :

    109655-83-6

  • Molecular Formula : C10H17NO4

  • Molecular Weight : 215.25

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661005

(1R,2R,4S,5S,7r)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol

(1R,2R,4S,5S,7r)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol


  • Catalogue No.:PA 20 0661005

  • CAS :

    498-46-4

  • Molecular Formula : C8H13NO2

  • Molecular Weight : 155.2

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661010

(1R,3s,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 3-hydroxy-2-phenylpropanoate

(1R,3s,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl 3-hydroxy-2-phenylpropanoate


  • Catalogue No.:PA 20 0661010

  • CAS :

    NA

  • Molecular Formula : C17H21NO3

  • Molecular Weight : 287.36

Drug Reference Standards & Impurity Synthesis in India
PA 20 0661011

(2RS,3aSR,5RS,6RS,6aRS)-6-Hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4- ium Bromide

(2RS,3aSR,5RS,6RS,6aRS)-6-Hydroxy-4,4-dimethylhexahydro-2H-2,5-methanofuro[3,2-b]pyrrol-4- ium Bromide


  • Catalogue No.:PA 20 0661011

  • CAS :

    NA

  • Molecular Formula : C9H16BrNO2

  • Molecular Weight : 250.14

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