Tovorafenib and its Impurities
Tovorafenib, known as Ojemda, is an oral, selective type II RAF kinase inhibitor for treating children aged 6 months and older with relapsed or refractory pediatric low-grade glioma (pLGG) having a BRAF fusion, rearrangement, or V600E mutation. Reference standards of Tovorafenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.