Tovorafenib and its Impurities

Tovorafenib, known as Ojemda, is an oral, selective type II RAF kinase inhibitor for treating children aged 6 months and older with relapsed or refractory pediatric low-grade glioma (pLGG) having a BRAF fusion, rearrangement, or V600E mutation. Reference standards of Tovorafenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 15 results for Tovorafenib Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 20 4120000

Tovorafenib

Tovorafenib


  • Catalogue No.:PA 20 4120000

  • CAS :

    1096708-71-2

  • Molecular Formula : C17H12Cl2F3N7O2S

  • Molecular Weight : 506.29

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121000

(R)-2-(1-Aminoethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide

(R)-2-(1-Aminoethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide


  • Catalogue No.:PA 20 4121000

  • CAS :

    1095823-62-3

  • Molecular Formula : C12H10ClF3N4OS

  • Molecular Weight : 350.74

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121001

6-Amino-5-chloropyrimidine-4-carboxylic Acid

6-Amino-5-chloropyrimidine-4-carboxylic Acid


  • Catalogue No.:PA 20 4121001

  • CAS :

    914916-98-6

  • Molecular Formula : C5H4ClN3O2

  • Molecular Weight : 173.56

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121002

S-Tovorafenib

S-Tovorafenib


  • Catalogue No.:PA 20 4121002

  • CAS :

    1096708-73-4

  • Molecular Formula : C17H12Cl2F3N7O2S

  • Molecular Weight : 506.29

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121003

4-(Trifluoromethyl)pyridine-2,6-diamine

4-(Trifluoromethyl)pyridine-2,6-diamine


  • Catalogue No.:PA 20 4121003

  • CAS :

    130171-52-7

  • Molecular Formula : C6H6F3N3

  • Molecular Weight : 177.13

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121004

3,5-Dichloro-4-(trifluoromethyl)pyridine-2,6-diamine

3,5-Dichloro-4-(trifluoromethyl)pyridine-2,6-diamine


  • Catalogue No.:PA 20 4121004

  • CAS :

    NA

  • Molecular Formula : C6H4Cl2F3N3

  • Molecular Weight : 246.01

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121005

3-Chloro-4-(trifluoromethyl)pyridine-2,6-diamine

3-Chloro-4-(trifluoromethyl)pyridine-2,6-diamine


  • Catalogue No.:PA 20 4121005

  • CAS :

    NA

  • Molecular Formula : C6H5ClF3N3

  • Molecular Weight : 211.57

Drug Reference Standards & Impurity Synthesis in India
PA STI 090230

Rac-Tovorafenib D3

Rac-Tovorafenib D3


  • Catalogue No.:PA STI 090230

  • CAS :

    NA

  • Molecular Formula : C17H9D3Cl2F3N7O2S

  • Molecular Weight : 509.3

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121006

6-Chloro-4-(trifluoromethyl)pyridin-2-amine

6-Chloro-4-(trifluoromethyl)pyridin-2-amine


  • Catalogue No.:PA 20 4121006

  • CAS :

    34486-23-2

  • Molecular Formula : C6H4ClF3N2

  • Molecular Weight : 196.56

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121007

5-Chloro-4-(trifluoromethyl)pyridin-3-amine

5-Chloro-4-(trifluoromethyl)pyridin-3-amine


  • Catalogue No.:PA 20 4121007

  • CAS :

    1019108-11-2

  • Molecular Formula : C6H4ClF3N2

  • Molecular Weight : 196.56

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121008

5-Chloro-6-(trifluoromethyl)pyridin-2-amine

5-Chloro-6-(trifluoromethyl)pyridin-2-amine


  • Catalogue No.:PA 20 4121008

  • CAS :

    1227595-72-3

  • Molecular Formula : C6H4ClF3N2

  • Molecular Weight : 196.56

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121009

3-Chloro-4-(trifluoromethyl)pyridine

3-Chloro-4-(trifluoromethyl)pyridine


  • Catalogue No.:PA 20 4121009

  • CAS :

    81565-19-7

  • Molecular Formula : C6H3ClF3N

  • Molecular Weight : 181.54

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121010

5-Chloropyrimidine-4-carboxylic Acid

5-Chloropyrimidine-4-carboxylic Acid


  • Catalogue No.:PA 20 4121010

  • CAS :

    64224-65-3

  • Molecular Formula : C5H3ClN2O2

  • Molecular Weight : 158.54

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121011

5-Amino-2,6-dichloropyrimidine-4-carboxylic Acid

5-Amino-2,6-dichloropyrimidine-4-carboxylic Acid


  • Catalogue No.:PA 20 4121011

  • CAS :

    1207176-09-7

  • Molecular Formula : C5H3Cl2N3O2

  • Molecular Weight : 208

Drug Reference Standards & Impurity Synthesis in India
PA 20 4121012

4-Amino-6-chloropyrimidine-5-carboxylic Acid

4-Amino-6-chloropyrimidine-5-carboxylic Acid


  • Catalogue No.:PA 20 4121012

  • CAS :

    1446111-08-5

  • Molecular Formula : C5H4ClN3O2

  • Molecular Weight : 173.56