trametinib and its Impurities

Trametinib may be used alone or in combination with another medication to treat a type of skin cancer. It is a MEK inhibitor drug with anti-cancer activity.Reference standards of Trametinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 31 results for trametinib Impurities
PA 47 14000

Trametinib

Trametinib

  • Catalogue No.:PA 47 14000

  • CAS :

    871700-17-3

  • Molecular Formula : C26H23FIN5O4

  • Molecular Weight : 615.39

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PA 47 14510

N-(3-(5-((4-Bromo-2-fluorophenyl)amino)-3-cyclopropyl-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

N-(3-(5-((4-Bromo-2-fluorophenyl)amino)-3-cyclopropyl-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

  • Catalogue No.:PA 47 14510

  • CAS :

    871700-13-9

  • Molecular Formula : C26H23BrFN5O4

  • Molecular Weight : 568.39

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PA 47 14520

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione

  • Catalogue No.:PA 47 14520

  • CAS :

    871700-22-0

  • Molecular Formula : C14H13FIN3O2

  • Molecular Weight : 401.17

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PA STI 084082

Trametinib-d4

Trametinib-d4

  • Catalogue No.:PA STI 084082

  • CAS :

    NA

  • Molecular Formula : C26H19D4FIN5O4

  • Molecular Weight : 619.42

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PA 47 0141000

Trametinib Dimethyl Sulfoxide

Trametinib Dimethyl Sulfoxide

  • Catalogue No.:PA 47 0141000

  • CAS :

    1187431-43-1

  • Molecular Formula : C28H29FIN5O5S

  • Molecular Weight : 693.53

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PA 47 0141001

1-(3-Aminophenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

1-(3-Aminophenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

  • Catalogue No.:PA 47 0141001

  • CAS :

    871701-87-0

  • Molecular Formula : C24H21FIN5O3

  • Molecular Weight : 573.37

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PA 47 0141002

1-(3-Amino-4-hydroxyphenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

1-(3-Amino-4-hydroxyphenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

  • Catalogue No.:PA 47 0141002

  • CAS :

    1620017-29-9

  • Molecular Formula : C24H21FIN5O4

  • Molecular Weight : 589.37

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PA 47 0141005

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

  • Catalogue No.:PA 47 0141005

  • CAS :

    871700-24-2

  • Molecular Formula : C18H15FIN3O4

  • Molecular Weight : 483.24

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PA 47 0141004

N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)amino)phenyl)acetamide

N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)amino)phenyl)acetamide

  • Catalogue No.:PA 47 0141004

  • CAS :

    871700-25-3

  • Molecular Formula : C26H23FIN5O4

  • Molecular Weight : 615.4

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PA 47 0141003

Desiodo Trametinib

Desiodo Trametinib

  • Catalogue No.:PA 47 0141003

  • CAS :

    871700-65-1

  • Molecular Formula : C26H24FN5O4

  • Molecular Weight : 489.51

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PA 47 0141006

N-Cyclopropyl-2-((2-fluoro-4-iodophenyl)amino)-4-hydroxy-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

N-Cyclopropyl-2-((2-fluoro-4-iodophenyl)amino)-4-hydroxy-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

  • Catalogue No.:PA 47 0141006

  • CAS :

    3018911-27-5

  • Molecular Formula : C17H17FIN3O3

  • Molecular Weight : 457.24

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PA 47 0141007

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

  • Catalogue No.:PA 47 0141007

  • CAS :

    1383430-03-2

  • Molecular Formula : C26H23FIN5O5

  • Molecular Weight : 631.4

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PA 47 0141008

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroperoxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroperoxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

  • Catalogue No.:PA 47 0141008

  • CAS :

    1383430-04-3

  • Molecular Formula : C26H23FIN5O6

  • Molecular Weight : 647.4

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PA 47 0141009

3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-1-(3-nitrophenyl)pyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-1-(3-nitrophenyl)pyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

  • Catalogue No.:PA 47 0141009

  • CAS :

    1279693-89-8

  • Molecular Formula : C24H19FIN5O5

  • Molecular Weight : 603.35

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PA 47 0141010

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)(nitroso)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)(nitroso)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

  • Catalogue No.:PA 47 0141010

  • CAS :

    NA

  • Molecular Formula : C26H22FIN6O5

  • Molecular Weight : 644.4

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PA 47 0141011

N-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-methylnitrous amide

N-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-methylnitrous amide

  • Catalogue No.:PA 47 0141011

  • CAS :

    NA

  • Molecular Formula : C14H12FIN4O3

  • Molecular Weight : 430.18

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PA 47 0141012

N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)(nitroso)amino)phenyl)acetamide

N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)(nitroso)amino)phenyl)acetamide

  • Catalogue No.:PA 47 0141012

  • CAS :

    NA

  • Molecular Formula : C26H22FIN6O5

  • Molecular Weight : 644.4

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PA 47 0141013

4-((3-Acetamidophenyl)amino)-N-cyclopropyl-2-((2-fluoro-4-iodophenyl)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

4-((3-Acetamidophenyl)amino)-N-cyclopropyl-2-((2-fluoro-4-iodophenyl)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

  • Catalogue No.:PA 47 0141013

  • CAS :

    NA

  • Molecular Formula : C25H25FIN5O3

  • Molecular Weight : 589.41

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PA 47 0141014

3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-1-(2-methylquinolin-7-yl)pyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-1-(2-methylquinolin-7-yl)pyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione

  • Catalogue No.:PA 47 0141014

  • CAS :

    NA

  • Molecular Formula : C28H23FIN5O3

  • Molecular Weight : 623.43

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PA 47 0141015

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl 4-methylbenzenesulfonate

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl 4-methylbenzenesulfonate

  • Catalogue No.:PA 47 0141015

  • CAS :

    871700-32-2

  • Molecular Formula : C25H21FIN3O6S

  • Molecular Weight : 637.42

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PA 47 0141016

3'-Aminoacetanilide

3'-Aminoacetanilide

  • Catalogue No.:PA 47 0141016

  • CAS :

    102-28-3

  • Molecular Formula : C8H10N2O

  • Molecular Weight : 150.18

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PA 47 0141017

N,N'-(1,3-Phenylene)diacetamide

N,N'-(1,3-Phenylene)diacetamide

  • Catalogue No.:PA 47 0141017

  • CAS :

    10268-78-7

  • Molecular Formula : C10H12N2O2

  • Molecular Weight : 192.22

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PA 47 0141018

N'-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N,N-dimethylformimidamide

N'-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N,N-dimethylformimidamide

  • Catalogue No.:PA 47 0141018

  • CAS :

    871700-30-0

  • Molecular Formula : C16H16FIN4O2

  • Molecular Weight : 442.23

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PA 47 0141019

N-(3-(3-Cyclopropyl-5-((2-fluorophenyl)(nitroso)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

N-(3-(3-Cyclopropyl-5-((2-fluorophenyl)(nitroso)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide

  • Catalogue No.:PA 47 0141019

  • CAS :

    NA

  • Molecular Formula : C26H23FN6O5

  • Molecular Weight : 518.51

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PA 47 0141020

N-(1-(3-Aminophenyl)-3-cyclopropyl-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,6,7-hexahydropyrido[4,3-d]pyrimidin-5-yl)-N-(2-fluoro-4-iodophenyl)nitrous amide

N-(1-(3-Aminophenyl)-3-cyclopropyl-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,6,7-hexahydropyrido[4,3-d]pyrimidin-5-yl)-N-(2-fluoro-4-iodophenyl)nitrous amide

  • Catalogue No.:PA 47 0141020

  • CAS :

    NA

  • Molecular Formula : C24H20FIN6O4

  • Molecular Weight : 602.36

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PA 47 0141021

4-((3-Acetamidophenyl)amino)-N-cyclopropyl-2-((2-fluoro-4-iodophenyl)(nitroso)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

4-((3-Acetamidophenyl)amino)-N-cyclopropyl-2-((2-fluoro-4-iodophenyl)(nitroso)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

  • Catalogue No.:PA 47 0141021

  • CAS :

    NA

  • Molecular Formula : C25H24FIN6O4

  • Molecular Weight : 618.41

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PA 47 0141022

4-((3-Acetamidophenyl)(nitroso)amino)-N-cyclopropyl-2-((2-fluoro-4-iodophenyl)(nitroso)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

4-((3-Acetamidophenyl)(nitroso)amino)-N-cyclopropyl-2-((2-fluoro-4-iodophenyl)(nitroso)amino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide

  • Catalogue No.:PA 47 0141022

  • CAS :

    NA

  • Molecular Formula : C25H23FIN7O5

  • Molecular Weight : 647.41

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PA 47 0141023

Desacetyl Trametinib N-Glucoronide

Desacetyl Trametinib N-Glucoronide

  • Catalogue No.:PA 47 0141023

  • CAS :

    NA

  • Molecular Formula : C30H29FIN5O9

  • Molecular Weight : 749.49

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PA 47 0141024

(2S,3S,4S,5R,6S)-6-(2-Amino-4-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid

(2S,3S,4S,5R,6S)-6-(2-Amino-4-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid

  • Catalogue No.:PA 47 0141024

  • CAS :

    1620017-28-8

  • Molecular Formula : C30H29FIN5O10

  • Molecular Weight : 765.49

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PA STI 089834

Trametinib-13C-d3

Trametinib-13C-d3

  • Catalogue No.:PA STI 089834

  • CAS :

    2712126-59-3

  • Molecular Formula : C2513CH20D3FIN5O4

  • Molecular Weight : 619.41

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PA STI 089917

Trametinib-d6

Trametinib-d6

  • Catalogue No.:PA STI 089917

  • CAS :

    2703263-38-9

  • Molecular Formula : C26H17D6FIN5O4

  • Molecular Weight : 621.44

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CPHI INDIA- 28, 30 November