Trifarotene and its Impurities
Trifarotene, sold under the brand name Aklief, is a medication for the topical treatment of acne vulgaris. Reference standards of Trifarotene API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Ethyl 4'-(2-acetoxyethoxy)-3''-(tert-butyl)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Ethyl 4'-(2-acetoxyethoxy)-3''-(tert-butyl)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Catalogue No.:PA 20 3341000
CAS :
895543-08-5
Molecular Formula : C33H39NO5
Molecular Weight : 529.68
Methyl 3''-(tert-butyl)-4'-(2-hydroxyethoxy)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Methyl 3''-(tert-butyl)-4'-(2-hydroxyethoxy)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Catalogue No.:PA 20 3341004
CAS :
895542-69-5
Molecular Formula : C30H35NO4
Molecular Weight : 473.61
Methyl 4'-(2-acetoxyethoxy)-3''-(tert-butyl)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Methyl 4'-(2-acetoxyethoxy)-3''-(tert-butyl)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Catalogue No.:PA 20 3341005
CAS :
3016428-47-7
Molecular Formula : C32H37NO5
Molecular Weight : 515.65
Ethyl 3''-(tert-butyl)-4'-(2-(2-hydroxyethoxy)ethoxy)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Ethyl 3''-(tert-butyl)-4'-(2-(2-hydroxyethoxy)ethoxy)-4''-(pyrrolidin-1-yl)-[1,1':3',1''-terphenyl]-4-carboxylate
Catalogue No.:PA 20 3341006
CAS :
NA
Molecular Formula : C33H41NO5
Molecular Weight : 531.69
